Structural analysis of the adenovirus type 2 E3/19K protein using mutagenesis and a panel of conformation-sensitive monoclonal antibodies

Molecular Immunology

Volumn 46, Issue 1, 2008, Pages 16-26

  Menz, Beatrice ^a   Sester, Martina ^b   Koebernick, Katja ^a   Schmid, Ralf ^c   Burgert, Hans Gerhard ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b SAARLAND UNIVERSITY   (Germany)

^c UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Adenovirus E3 19K; Antigen presentation; Immune evasion; Monoclonal antibody epitope mapping

Indexed keywords

HISTIDINE TAGGED ADENOVIRUS E3 PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; POLYHISTIDINE TAG; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ADENOVIRUS 2; ADENOVIRUS 5; ALPHA HELIX; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; ARTICLE; BETA SHEET; CARBOXY TERMINAL SEQUENCE; CELL SURFACE; CONTROLLED STUDY; DOWN REGULATION; ENDOPLASMIC RETICULUM; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; GENE MUTATION; GENE SEQUENCE; HUMAN; HUMAN CELL; IMMUNIZATION; IMMUNOPRECIPITATION; LIGAND BINDING; MOUSE; MUTAGENESIS; NATURAL KILLER T CELL; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; SITE DIRECTED MUTAGENESIS; VIRUS INFECTION; WESTERN BLOTTING; WILD TYPE;

ADENOVIRUS E3 PROTEINS; ALANINE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY SPECIFICITY; BINDING, COMPETITIVE; CARBOHYDRATES; CELL LINE; CONSERVED SEQUENCE; CYSTEINE; EPITOPES; HUMANS; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTANT PROTEINS; MUTATION; PEPTIDE MAPPING; PROTEIN CONFORMATION; RECOMBINANT PROTEINS;

ADENOVIRIDAE; HUMAN ADENOVIRUS TYPE 2;

EID: 53049097272     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2008.06.019     Document Type: Article

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