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Volumn 14, Issue 17, 2008, Pages 5484-5493

Effective CpG immunotherapy of breast carcinoma prevents but fails to eradicate established brain metastasis

Author keywords

[No Author keywords available]

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; CPG OLIGONUCLEOTIDE; CPG-OLIGONUCLEOTIDE; IMMUNOLOGICAL ADJUVANT; OLIGODEOXYRIBONUCLEOTIDE;

EID: 53049095387     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-07-4139     Document Type: Article
Times cited : (20)

References (38)
  • 2
    • 0037376830 scopus 로고    scopus 로고
    • Determinants and prognoses of locoregional and distant progression in breast cancer
    • Engel J, Eckel R, Aydemir U, et al. Determinants and prognoses of locoregional and distant progression in breast cancer. Int J Radiat Oncol Biol Phys 2003;55:1186-95.
    • (2003) Int J Radiat Oncol Biol Phys , vol.55 , pp. 1186-1195
    • Engel, J.1    Eckel, R.2    Aydemir, U.3
  • 4
    • 33747346235 scopus 로고    scopus 로고
    • Signal integration between IFNγ and TLR signalling pathways in macrophages
    • Schroder K, Sweet MJ, Hume DA. Signal integration between IFNγ and TLR signalling pathways in macrophages. Immunobiology 2006;211:511-24.
    • (2006) Immunobiology , vol.211 , pp. 511-524
    • Schroder, K.1    Sweet, M.J.2    Hume, D.A.3
  • 5
    • 33749148761 scopus 로고    scopus 로고
    • CpG DNA activates survival in murine macrophages throughTLR9 and the phosphatidylinositol 3-kinase-Akt pathway
    • Sester DP, Brion K,Trieu A, et al. CpG DNA activates survival in murine macrophages throughTLR9 and the phosphatidylinositol 3-kinase-Akt pathway. J Immunol 2006;177:4473-80.
    • (2006) J Immunol , vol.177 , pp. 4473-4480
    • Sester, D.P.1    Brion, K.2    Trieu, A.3
  • 6
    • 33750934617 scopus 로고    scopus 로고
    • Steinman RM, Hemmi H. Dendritic cells: translating innate to adaptive immunity. CurrTop Microbiol Immunol 2006;311:17-58.
    • Steinman RM, Hemmi H. Dendritic cells: translating innate to adaptive immunity. CurrTop Microbiol Immunol 2006;311:17-58.
  • 7
    • 33745946911 scopus 로고    scopus 로고
    • Therapeutic potential of Toll-like receptor 9 activation
    • Krieg AM. Therapeutic potential of Toll-like receptor 9 activation. Nat Rev Drug Discov 2006;5:471-84.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 471-484
    • Krieg, A.M.1
  • 8
    • 0033230505 scopus 로고    scopus 로고
    • Oligodeoxynucleotides containing CpG motifs can induce rejection of a neuroblastoma in mice
    • Carpentier AF, Chen L, Maltonti F, Delattre JY. Oligodeoxynucleotides containing CpG motifs can induce rejection of a neuroblastoma in mice. Cancer Res 1999;59:5429-32.
    • (1999) Cancer Res , vol.59 , pp. 5429-5432
    • Carpentier, A.F.1    Chen, L.2    Maltonti, F.3    Delattre, J.Y.4
  • 9
    • 0034087729 scopus 로고    scopus 로고
    • Successful treatment of intracranial gliomas in rat by oligodeoxynucleotides containing CpG motifs
    • Carpentier AF, Xie J, Mokhtari K, Delattre JY. Successful treatment of intracranial gliomas in rat by oligodeoxynucleotides containing CpG motifs. Clin Cancer Res 2000;6:2469-73.
    • (2000) Clin Cancer Res , vol.6 , pp. 2469-2473
    • Carpentier, A.F.1    Xie, J.2    Mokhtari, K.3    Delattre, J.Y.4
  • 10
    • 0035500280 scopus 로고    scopus 로고
    • NK- and CD8( + ) T cell-mediated eradication of established tumors by peritumoral injection of CpG-containing oligodeoxynucleotides
    • Kawarada Y, Ganss R, Garbi N, Sacher T, Arnold B, Hammerling GJ. NK- and CD8( + ) T cell-mediated eradication of established tumors by peritumoral injection of CpG-containing oligodeoxynucleotides. J Immunol 2001;167:5247-53.
    • (2001) J Immunol , vol.167 , pp. 5247-5253
    • Kawarada, Y.1    Ganss, R.2    Garbi, N.3    Sacher, T.4    Arnold, B.5    Hammerling, G.J.6
  • 11
    • 31544468075 scopus 로고    scopus 로고
    • Phase 1 trial of a CpG oligodeoxynucleotide for patients with recurrent glioblastoma
    • Carpentier A, Laigle-Donadey F, Zohar S, et al. Phase 1 trial of a CpG oligodeoxynucleotide for patients with recurrent glioblastoma. Neurooncol 2006;8:60-6.
    • (2006) Neurooncol , vol.8 , pp. 60-66
    • Carpentier, A.1    Laigle-Donadey, F.2    Zohar, S.3
  • 12
    • 34247389227 scopus 로고    scopus 로고
    • Phase II trial of a toll-like receptor 9-activating oligonucleotide in patients with metastatic melanoma
    • Pashenkov M, Goess G, Wagner C, et al. Phase II trial of a toll-like receptor 9-activating oligonucleotide in patients with metastatic melanoma. J Clin Oncol 2006;24:5716-24.
    • (2006) J Clin Oncol , vol.24 , pp. 5716-5724
    • Pashenkov, M.1    Goess, G.2    Wagner, C.3
  • 13
    • 33847080492 scopus 로고    scopus 로고
    • Peptide vaccine given with a Toll-like receptor agonist is effective for thetreatment and prevention of spontaneous breast tumors
    • Nava-Parada P, Forni G, Knutson KL, Pease LR, Celis E. Peptide vaccine given with a Toll-like receptor agonist is effective for thetreatment and prevention of spontaneous breast tumors. Cancer Res 2007;67:1326-34.
    • (2007) Cancer Res , vol.67 , pp. 1326-1334
    • Nava-Parada, P.1    Forni, G.2    Knutson, K.L.3    Pease, L.R.4    Celis, E.5
  • 14
    • 0346096827 scopus 로고    scopus 로고
    • The first 1000 dendritic cell vaccinees
    • Ridgway D. The first 1000 dendritic cell vaccinees. Cancer Invest 2003;21:873-86.
    • (2003) Cancer Invest , vol.21 , pp. 873-886
    • Ridgway, D.1
  • 15
    • 27744497800 scopus 로고    scopus 로고
    • Combinatorial antiangiogenic gene therapy by nonviral gene transfer using the sleeping beauty transposon causes tumor regression and improves survival in mice bearing intracranial human glioblastoma
    • Ohlfest JR, Demorest ZL, Motooka Y, et al. Combinatorial antiangiogenic gene therapy by nonviral gene transfer using the sleeping beauty transposon causes tumor regression and improves survival in mice bearing intracranial human glioblastoma. Mol Ther 2005;12:778-88.
    • (2005) Mol Ther , vol.12 , pp. 778-788
    • Ohlfest, J.R.1    Demorest, Z.L.2    Motooka, Y.3
  • 16
    • 34249056542 scopus 로고    scopus 로고
    • Transposon-based interferon γ gene transfer overcomes limitations of episomal plasmid for immunogene therapy of glioblastoma
    • Wu A, Oh S, Ericson K, et al. Transposon-based interferon γ gene transfer overcomes limitations of episomal plasmid for immunogene therapy of glioblastoma. Cancer Gene Ther 2007;14:550-60.
    • (2007) Cancer Gene Ther , vol.14 , pp. 550-560
    • Wu, A.1    Oh, S.2    Ericson, K.3
  • 17
    • 30944437887 scopus 로고    scopus 로고
    • Toll-like receptor 9-mediated induction of the immunosuppressive pathway of tryptophan catabolism
    • Fallarino F, Puccetti P. Toll-like receptor 9-mediated induction of the immunosuppressive pathway of tryptophan catabolism. Eur J Immunol 2006;36:8-11.
    • (2006) Eur J Immunol , vol.36 , pp. 8-11
    • Fallarino, F.1    Puccetti, P.2
  • 18
    • 33646419260 scopus 로고    scopus 로고
    • Agonist anti-GITRantibody enhances vaccine-induced CD8(+) T-cell responses and tumor immunity
    • Cohen AD, Diab A, Perales MA, et al. Agonist anti-GITRantibody enhances vaccine-induced CD8(+) T-cell responses and tumor immunity. Cancer Res 2006;66:4904-12.
    • (2006) Cancer Res , vol.66 , pp. 4904-4912
    • Cohen, A.D.1    Diab, A.2    Perales, M.A.3
  • 19
    • 0042700227 scopus 로고    scopus 로고
    • Gene transfer into genomes of human cells by the sleeping beautytransposon system
    • Geurts AM,Yang Y, Clark KJ, et al. Gene transfer into genomes of human cells by the sleeping beautytransposon system. Mol Ther 2003;8:108-17.
    • (2003) Mol Ther , vol.8 , pp. 108-117
    • Geurts, A.M.1    Yang, Y.2    Clark, K.J.3
  • 20
    • 33749003484 scopus 로고    scopus 로고
    • El Andaloussi A, Sonabend AM, HanY, Lesniak MS. Stimulation of TLR9 with CpG ODN enhances apoptosis of glioma and prolongs the survival of mice with experimental brain tumors. Glia 2006;54:526-35.
    • El Andaloussi A, Sonabend AM, HanY, Lesniak MS. Stimulation of TLR9 with CpG ODN enhances apoptosis of glioma and prolongs the survival of mice with experimental brain tumors. Glia 2006;54:526-35.
  • 21
    • 34248172651 scopus 로고    scopus 로고
    • CD4+FoxP3+ regulatory T cells gradually accumulate in gliomas during tumor growth and efficiently suppress antiglioma immune responses in vivo
    • Grauer OM, Nierkens S, Bennink E, et al. CD4+FoxP3+ regulatory T cells gradually accumulate in gliomas during tumor growth and efficiently suppress antiglioma immune responses in vivo. Int J Cancer 2007;121:95-105.
    • (2007) Int J Cancer , vol.121 , pp. 95-105
    • Grauer, O.M.1    Nierkens, S.2    Bennink, E.3
  • 22
    • 30644470953 scopus 로고    scopus 로고
    • Gasparini G, Longo R,Torino F, Morabito A. Therapy of breast cancer with molecular targeting agents. Ann Oncol 2005;16 Suppl 4:iv28-36.
    • Gasparini G, Longo R,Torino F, Morabito A. Therapy of breast cancer with molecular targeting agents. Ann Oncol 2005;16 Suppl 4:iv28-36.
  • 23
    • 34247346051 scopus 로고    scopus 로고
    • Prognosticsignificance of human epidermal growth factor receptor positivity for the development of brain metastasis after newly diagnosed breast cancer
    • Gabos Z, Sinha R, Hanson J, et al. Prognosticsignificance of human epidermal growth factor receptor positivity for the development of brain metastasis after newly diagnosed breast cancer. J Clin Oncol 2006;24:5658-63.
    • (2006) J Clin Oncol , vol.24 , pp. 5658-5663
    • Gabos, Z.1    Sinha, R.2    Hanson, J.3
  • 24
    • 0142259710 scopus 로고    scopus 로고
    • Three or more routes for leukocyte migration into the central nervous system
    • Ransohoff RM, Kivisakk P, Kidd G. Three or more routes for leukocyte migration into the central nervous system. Nat Rev Immunol 2003;3:569-81.
    • (2003) Nat Rev Immunol , vol.3 , pp. 569-581
    • Ransohoff, R.M.1    Kivisakk, P.2    Kidd, G.3
  • 25
    • 0034691208 scopus 로고    scopus 로고
    • Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: Toward realistic long-term neurological gene therapy for chronic diseases
    • Thomas CE, Schiedner G, Kochanek S, Castro MG, Lowenstein PR. Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: toward realistic long-term neurological gene therapy for chronic diseases. Proc Natl Acad Sci U S A 2000;97:7482-7.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 7482-7487
    • Thomas, C.E.1    Schiedner, G.2    Kochanek, S.3    Castro, M.G.4    Lowenstein, P.R.5
  • 26
    • 0034926344 scopus 로고    scopus 로고
    • Preexisting antiadenoviral immunityis not a barrier to efficient and stable transduction of the brain, mediated by novel high-capacity adenovirus vectors
    • Thomas CE, Schiedner G, Kochanek S, Castro MG, Lowenstein PR. Preexisting antiadenoviral immunityis not a barrier to efficient and stable transduction of the brain, mediated by novel high-capacity adenovirus vectors. Hum GeneTher 2001;12:839-46.
    • (2001) Hum GeneTher , vol.12 , pp. 839-846
    • Thomas, C.E.1    Schiedner, G.2    Kochanek, S.3    Castro, M.G.4    Lowenstein, P.R.5
  • 27
    • 20844463069 scopus 로고    scopus 로고
    • Stability of lentiviral vector-mediated transgene expression in the brain in the presence of systemic antivector immune responses
    • Abordo-Adesida E, Follenzi A, Barcia C, et al. Stability of lentiviral vector-mediated transgene expression in the brain in the presence of systemic antivector immune responses. Hum GeneTher 2005;16:741-51.
    • (2005) Hum GeneTher , vol.16 , pp. 741-751
    • Abordo-Adesida, E.1    Follenzi, A.2    Barcia, C.3
  • 28
    • 3042766303 scopus 로고    scopus 로고
    • Intracerebral infection with murine cytomegalovirus induces CXCL10 and is restricted by adoptive transfer of splenocytes
    • Cheeran MC, Gekker G, Hu S, Min X, Cox D, Lokensgard JR. Intracerebral infection with murine cytomegalovirus induces CXCL10 and is restricted by adoptive transfer of splenocytes. J Neurovirol 2004;10:152-62.
    • (2004) J Neurovirol , vol.10 , pp. 152-162
    • Cheeran, M.C.1    Gekker, G.2    Hu, S.3    Min, X.4    Cox, D.5    Lokensgard, J.R.6
  • 29
    • 23744458320 scopus 로고    scopus 로고
    • Tcell-mediated restriction of intracerebral murine cytomegalovirus infection displaysdependence upon perforin but not interferon-γ
    • Cheeran MC, Gekker G, HuS, Palmquist JM, Lokensgard JR. Tcell-mediated restriction of intracerebral murine cytomegalovirus infection displaysdependence upon perforin but not interferon-γ. J Neurovirol 2005;11:274-80.
    • (2005) J Neurovirol , vol.11 , pp. 274-280
    • Cheeran, M.C.1    Gekker, G.2    Hu, S.3    Palmquist, J.M.4    Lokensgard, J.R.5
  • 31
    • 0041562407 scopus 로고    scopus 로고
    • The history, evolution, and clinical use of dendritic cell-based immunization strategies in the therapy of brain tumors
    • Fecci PE, Mitchell DA, Archer GE, et al. The history, evolution, and clinical use of dendritic cell-based immunization strategies in the therapy of brain tumors. J Neurooncol2003;64:161-76.
    • J Neurooncol2003;64 , pp. 161-176
    • Fecci, P.E.1    Mitchell, D.A.2    Archer, G.E.3
  • 32
    • 61349138567 scopus 로고    scopus 로고
    • Weigel BJ, Rodeberg DA, Krieg AM, Blazar BR
    • Weigel BJ, Rodeberg DA, Krieg AM, Blazar BR.
  • 33
    • 0042024964 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides potentiate the antitumor effects of chemotherapy or tumor resection in an orthotopic murine model of rhabdomyosarcoma. Clin Cancer Res 2003;9:3105-14
    • CpG oligodeoxynucleotides potentiate the antitumor effects of chemotherapy or tumor resection in an orthotopic murine model of rhabdomyosarcoma. Clin Cancer Res 2003;9:3105-14.
  • 34
    • 37349114848 scopus 로고    scopus 로고
    • In vivo vaccination with tumor cell lysate plus CpG oligodeoxynucleotides eradicates murine glioblastoma
    • Wu A, Oh S, Gharagozlou S, et al. In vivo vaccination with tumor cell lysate plus CpG oligodeoxynucleotides eradicates murine glioblastoma. J Immunother 2007;30:789-97.
    • (2007) J Immunother , vol.30 , pp. 789-797
    • Wu, A.1    Oh, S.2    Gharagozlou, S.3
  • 35
    • 33845885624 scopus 로고    scopus 로고
    • Systemic anti-CD25 monoclonal antibody administration safely enhances immunity in murine glioma without eliminating regulatory T cells
    • Fecci PE, Sweeney AE, Grossi PM, et al. Systemic anti-CD25 monoclonal antibody administration safely enhances immunity in murine glioma without eliminating regulatory T cells. Clin Cancer Res 2006;12:4294-305.
    • (2006) Clin Cancer Res , vol.12 , pp. 4294-4305
    • Fecci, P.E.1    Sweeney, A.E.2    Grossi, P.M.3
  • 36
    • 33748492962 scopus 로고    scopus 로고
    • Prolongation of survival following depletion of CD4+CD25+ regulatory T cells in mice with experimental brain tumors
    • El Andaloussi A, Han Y, Lesniak MS. Prolongation of survival following depletion of CD4+CD25+ regulatory T cells in mice with experimental brain tumors. J Neurosurg 2006;105:430-7.
    • (2006) J Neurosurg , vol.105 , pp. 430-437
    • El Andaloussi, A.1    Han, Y.2    Lesniak, M.S.3
  • 37
    • 20344372430 scopus 로고    scopus 로고
    • Clinical evaluation of dendriticcell vaccination for patients with recurrent glioma: Results of a clinical phase I/II trial
    • Yamanaka R, Homma J,Yajima N, et al. Clinical evaluation of dendriticcell vaccination for patients with recurrent glioma: results of a clinical phase I/II trial. Clin Cancer Res 2005;11:4160-7.
    • (2005) Clin Cancer Res , vol.11 , pp. 4160-4167
    • Yamanaka, R.1    Homma, J.2    Yajima, N.3
  • 38
    • 24944546501 scopus 로고    scopus 로고
    • Immunomonitoring tumor-specific T cells in delayed-type hypersensitivityskin biopsies after dendriticcell vaccination correlates with clinical outcome
    • de Vries IJ, Bernsen MR, Lesterhuis WJ, et al. Immunomonitoring tumor-specific T cells in delayed-type hypersensitivityskin biopsies after dendriticcell vaccination correlates with clinical outcome. J Clin Oncol 2005;23:5779-87.
    • (2005) J Clin Oncol , vol.23 , pp. 5779-5787
    • de Vries, I.J.1    Bernsen, M.R.2    Lesterhuis, W.J.3


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