Mass transfer model for drug delivery in tissue cells with reversible electroporation

International Journal of Heat and Mass Transfer

Volumn 51, Issue 23-24, 2008, Pages 5610-5616

  Granot, Yair ^a   Rubinsky, Boris ^b,c,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b University of California at Berkeley   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Electrochemotherapy; Mass transfer; Single cell electroporation model; Tissue electroporation

Indexed keywords

CELLS; CHEMOTHERAPY; CYTOLOGY; DRUG DELIVERY; DRUG DOSAGE; ELECTRODES; HEALTH; MASS TRANSFER; MATHEMATICAL MODELS; METALLIZING; SUPRAMOLECULAR CHEMISTRY; TISSUE;

ANTI-CANCER DRUGS; BLEOMYCIN; CYTOSOL; ELECTRICAL FIELDS; ELECTRICAL PULSES; ELECTROCHEMOTHERAPY; ELECTROPORATION; MACROSCOPIC MASS; MACROSCOPIC MODELING; MASS TRANSFER MODELING; MOLECULAR MEDICINES; NANO-SCALE PORES; PERMEABILIZATION; SCALE MODELING; SINGLE CELL ELECTROPORATION MODEL; TISSUE CELLS; TISSUE ELECTROPORATION;

CELL MEMBRANES;

EID: 53049091831     PISSN: 00179310     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijheatmasstransfer.2008.04.041     Document Type: Article

References (31)

1. Mir L.M., and Orlowski S. Mechanisms of electrochemotherapy. Adv. Drug Deliver. Rev. 35 (1999) 07-118
2. Weaver J.C., and Chizmadzhev Y.A. Theory of electroporation: a review. Bioelectrochem. Bioenerg. 41 (1996) 135-160
3. Chang D.C., Chassy B.M., Saunders J.A., and Sowers A.E. Guide to Electroporation and Electrofusion (1992), Academic Press, Inc., San Diego, CA
4. Satkauskas S., Bureau M.F., Puc M., Mahfoudi A., Scherman D., Miklavcic D., and Mir L.M. Mechnisms of in vivo DNA electrotransfer: respective contributions of cell electropermeabilization and DNA electrophoresis. Mol. Ther. 5 (2002) 133-140
5. Coster H.G.A. Quantitative analysis of the voltage-current relationship of fixed charge membranes and the associated property of "punch-through". Biophys. J. 5 (1965) 669-686
6. Sale A.J., and Hamilton W.A. Effects of high electric fields on micro-organisms. 1. Killing of bacteria and yeasts. Biochim. Biophys. Acta 148 (1967) 781-788
7. Neumann E., and Rosenheck K. Permeability changes induced by electric impulses in vesicular membranes. J. Membrane Biol. 10 (1972) 279-290
8. Crowley J.M. Electrical breakdown of biomolecular lipid membranes as an electromechanical instability. Biophys. J. 13 (1973) 711-724
9. Zimmermann U., Vienken J., and Pilwat G. Dielectric breakdown of cell membranes. Biophys. J. 14 (1974) 881-899
10. Kinosita Jr. K., and Tsong T.Y. Hemolysis of human erythrocytes by a transient electric field. Proc. Natl. Acad. Sci. USA 74 (1977) 1923-1927
11. Baker P.F., and Knight D.E. Calcium-dependent exocytosis in bovine adrenal medullary cells with leaky plasma membranes. Nature 276 (1978) 620-622
12. Gauger B., and Bentrup F.W. A study of dielectric membrane breakdown in the fucus egg. J. Membrane Biol. 48 (1979) 249-264
13. Neumann E., Schaefer-Ridder M., Wang Y., and Hofschneider P.H. Gene transfer into mouse lyoma cells by electroporation in high electric fields. J. EMBO 1 (1982) 841-845
14. Okino M., and Mohri H. Effects of a high-voltage electrical impulse and an anticancer drug on in vivo growing tumors. Jpn. J. Cancer Res. 78 (1987) 1319-1321
15. Mir L.M., Orlowski S., Belehradek Jr. J., and Paoletti C. Electrochemotherapy potentiation of antitumour effect of bleomycin by local electric pulses. Eur. J. Cancer 27 (1991) 68-72
16. Mir L.M., Belehradek M., Domenge C., Luboniski B., Orlowski S., Belehradek J., Schwaab B., Luboniski B., and Paoletti C. Electrochemotherapy, a novel antitumor treatment: first clinical trial. C. R. Acad. Sci. Ser. III 313 (1991)
17. Mir L.M. Therapeutic perspectives of in vivo cell electropermeabilization. Bioelectrochemistry 53 (2001) 1-10
18. Poddevin B., Orlowski S., Belehradek J., and Mir L.M. Very high cytotoxicity of bleomycin introduced into the cytosol of cells in culture. Biochem. Pharmacol. 42 (1991) S67-S75
19. Tounekti O., Pron G., Belehradek Jr. J., and Mir L.M. Bleomycin, an apoptosis-mimetic drug that induces two types of cell death depending on the number of molecules internalized. Cancer Res. 53 (1993) 5462-5469
20. Jaroszeski M.J., Gilbert R., Nicolau C., and Heller R. In vivo gene delivery by electroporation. Adv. Appl. Electrochem. 35 (1999) 131-137
21. Jaroszeski M.J., Gilbert R., Nicolau C., and Heller R. In vivo gene delivery by electroporation. Adv. Drug Deliver. Rev. 35 (1999) 131-137
22. R.V. Davalos, Real time imaging for molecular medicine through electrical impedance tomography of electroporation, PhD Thesis, Mechanical Engineering Department, UC Berkeley, Berkeley, CA, 2002.
23. Sersa G. The state-of-the-art of electrochemotherapy before the ESOPE study; advantages and clinical uses. Eur. J. Cancer Suppl. 4 (2006) 52-59
24. Mir L.M., Glass L.F., Sersa G., Teissie J., Domenge C., Miklavcic D., Jaroszeski M.J., Orlowski S., Reintgen D.S., Rudolf Z., Belehradek M., Gilbert R., Rols M.P., Belehradek J., Bachaud J.M., Deconti R., Stabuc B., Cemazar M., Coninx P., and Heller R. Effective treatment of cutaneous and subcutaneous malignant tumours by electrochemotherapy. Brit. J. Cancer 77 (1998) 2336-2342
25. Dev S.B., Rabussay D.P., Widera G., and Hofmann G.A. Medical applications of electroporation. IEEE Trans. Plasma Sci. 28 (2000) 206-223
26. Engstrom P.E., Persson B.R.R., and Salford L.G. Studies of in vivo electropermeabilization by gamma camera measurements of 99mTc-DTPA. Biochim. Biophys. Acta (BBA) - Gen. Subjects 1473 (1999) 321-328
27. Miklavcic D., Semrov D., Mekid H., and Mir L.M. A validated model of in vivo electric field distribution in tissues for electrochemotherapy and for DNA electrotransfer for gene therapy. Biochim. Biophys. Acta (BBA) - Gen. Subjects 1523 (2000) 73-83
28. Krassowska W., and Filev P.D. Modeling electroporation in a single cell. Biophys. J. 92 (2007) 404-417
29. Neumann E., Sowers A.E., and Jordan C.A. Electroporation and Electrofusion in Cell Biology (1989), Springer
30. Esser A.T., Smith K.C., Gowrishankar T.R., and Weaver J.C. Towards solid tumor treatment by irreversible electroporation: intrinsic redistribution of fields and currents in tissue. Technol. Cancer Res. Treat. 6 (2007) 261-274
31. Neumann E., Toensing K., Kakorin S., Budde P., and Frey J. Mechanism of electroporative dye uptake by mouse B cells. Biophys. J. 74 (1998) 98-108