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Journal of Combinatorial Chemistry

Volumn 10, Issue 5, 2008, Pages 655-657

Preparation of a library of unsymmetrical ureas based on 8-azabicyclo[3.2.1]octane scaffold

(2) Agarkov, Anton a Gilbertson, Scott R a

a University of Texas Medical Branch School of Medicine (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; CHLORINATED HYDROCARBON; NORTROPANE DERIVATIVE; SOLVENT; TROPANE DERIVATIVE; UREA;

ARTICLE; CHEMICAL MODEL; CHEMISTRY; COMBINATORIAL CHEMISTRY; METHODOLOGY; MOLECULAR WEIGHT; SOLUBILITY; SYNTHESIS;

AMINES; COMBINATORIAL CHEMISTRY TECHNIQUES; HYDROCARBONS, CHLORINATED; MODELS, CHEMICAL; MOLECULAR WEIGHT; NORTROPANES; SOLUBILITY; SOLVENTS; TROPANES; UREA;

EID: 53049091284 PISSN: 15204766 EISSN: None Source Type: Journal
DOI: 10.1021/cc800068k Document Type: Article

Times cited : (10)

References (11)

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- Meltzer, P.C.¹ Liang, A.Y.² Madras, B.K.³

5
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- It was reported for the same system that the demethylation can be done using phosgene only, but it has not been attempted in this project. Banholzer, R.; Heusner, A.; Schulz, W. Liebigs Ann. Chem. 1975, 12, 2227-2231.
- It was reported for the same system that the demethylation can be done using phosgene only, but it has not been attempted in this project. Banholzer, R.; Heusner, A.; Schulz, W. Liebigs Ann. Chem. 1975, 12, 2227-2231.

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- Olofson, R.A.¹ Martz, J.T.² Senet, J.P.³ Piteau, M.⁴ Malfroot, T.⁵

7
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- These 15 compounds have not been prepared: 8{1,17}, 8{1,22}, 8{1,24}, 8{2,12}, 8{2,17}, 8{2,20}, 8{2,22}, 8{2,23}, 8{2,24}, 8{6,6}, 8{6,9}, 8{6,10}, 8{6,18}, 8{6,19}, 8{6,21}.
- These 15 compounds have not been prepared: 8{1,17}, 8{1,22}, 8{1,24}, 8{2,12}, 8{2,17}, 8{2,20}, 8{2,22}, 8{2,23}, 8{2,24}, 8{6,6}, 8{6,9}, 8{6,10}, 8{6,18}, 8{6,19}, 8{6,21}.

8
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- A function CHEM.NUM.HBACCEPTORS(structure) of ChemDraw for Excel from ChemDraw Ultra 10.0 package by CambridgeSoft was used.
- A function CHEM.NUM.HBACCEPTORS(structure) of ChemDraw for Excel from ChemDraw Ultra 10.0 package by CambridgeSoft was used.

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- A function CHEM.NUM.HBDONORS(structure) of ChemDraw for Excel from ChemDraw Ultra 10.0 package by CambridgeSoft was used.
- A function CHEM.NUM.HBDONORS(structure) of ChemDraw for Excel from ChemDraw Ultra 10.0 package by CambridgeSoft was used.

10
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- Thiazolidine and 2-(methylthio)ethylarnine were excluded from the library synthesis because of oxidation of the sulfur (+16 peak in LC-MS).
- Thiazolidine and 2-(methylthio)ethylarnine were excluded from the library synthesis because of oxidation of the sulfur (+16 peak in LC-MS).

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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.