Expressions of voltage-gated K+ channel 2.1 and 2.2 in rat bladder with detrusor hyperreflexia

Chinese Medical Journal

Volumn 121, Issue 16, 2008, Pages 1574-1577

  Gan, Xiu Guo ^a   An, Rui Hua ^a   Bai, Yu Feng ^a   Zong, De Bin ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Overactive detrusor; Potassium voltage gated channel; Spinal cord injury

Indexed keywords

4 AMINOPYRIDINE; BETA ACTIN; MESSENGER RNA; SHAB POTASSIUM CHANNEL; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL KV2.1; VOLTAGE GATED POTASSIUM CHANNEL KV2.2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER CAPACITY; BLADDER CONTRACTION; CONTROLLED STUDY; CYSTOMETRY; DETRUSOR MUSCLE; FEMALE; IN VIVO STUDY; MICTURITION; NONHUMAN; OVERACTIVE BLADDER; PROTEIN EXPRESSION; PROTEIN TARGETING; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SPINAL CORD INJURY;

EID: 52949144865     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00029330-200808020-00014     Document Type: Article

References (21)

1. + channels regulate action potential repolarization in urinary bladder smooth muscle. Am J Physiol 1997; 273: 110-117.
2. Zhang YC, Ni W, Zhang ZK, Xu YJ. The effect of protein kinase C on voltage-gated potassium channel in pulmonary artery smooth muscle cells from rats exposed to chronic hypoxia. Chin Med J 2004; 117: 19-23.
3. Zhao LM, Xu YJ, Zhang ZX, Ni W, Chen SX. Effect of passive sensitization by serum from allergic asthmatic patients on the activity and expression of voltage-dependent delayed rectifier potassium channel in human bronchial smooth muscle cells. Chin Med J 2004; 117: 1630-1636.
4. + channel diversity in the mammalian myocardium. J Physiol 2000; 525: 285-298.
5. Rudy B, Chow A, Lau D, Amarillo Y, Ozaita A, Saganich M, et al. Contributions of Kv3 channels to neuronal excitability. Ann N Y Acad Sci 1999; 868: 304-343.
6. + channel to regulation by PKA and PKC is partially lost in BEK 293 host cells. J Membr Biol 1998; 161: 183-196.
7. Ottschytsch N, Raes A, Van Hoorick D, Snyders DJ. Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome. Proc Natl Acad Sci U S A 2002; 99: 7986-7991.
8. + current. J Physiol 2003; 549: 65-74.
9. Zong DB, Gan XG, Wang Y, An RH. Correlation between voltage gated potassium channels and detrusor instability. Chin J Urol (Chin) 2007; 28: 414-416.
10. Oner-Iyidoǧan Y, Koçak H, Gürdöl F, Koçak T, Erol B. Urine 8-isoprostane F2 alpha concentrations in patients with neurogenic bladder due to spinal cord injury. Clin Chim Acta 2004; 339: 43-47.
11. Sweeney M, Yuan JXJ. Hypoxic pulmonary vasoconstriction:role of voltage-gated potassium channels. Respir Res 2000; 1: 40-48.
12. Lin ATL, Chen MT, Yang CH. Blood flow of the urinary bladder: effects of outlet obstruction and correlation with bioenergetic metabolism. Neurourol Urodyn 1995; 14: 285-292.
13. + channel in 24 hour-hypoxic human pulmonary artery smooth muscle cells. Chin Med J 2005; 118: 12-19.
14. + channel subtype transcripts in several types of smooth muscles of the rat. J Smooth Muscle Res 2000; 36: 101-115.
15. Yoshimura N. Bladder afferent pathway and spinal cord injury: possible mechanisms inducing hyperreflexia of the urinary bladder. Prog Neurobiol 1999; 57: 583-606.
16. Thomas C, Kim JH, Torimoto K, Kwon DD, Kim YT, Tyagi P, et al. Early capsaicin intervention for neurogenic bladder in a rat model of spinal cord injury. Biomed Res 2007; 28: 255-259.
17. Yoshiyama M, de Groat WC. Supraspinal and spinal alphaamino-3-hydroxy-5-methylisoxazole-4-propionic acid and Nmethyl-D-aspartate glutamatergic control of the micturition reflex in the urethane-anesthetized rat. Neuroscience 2005; 132: 1017-1026.
18. Cheng CL, de Groat WC. The role of capsaicin-sensitive afferent fibers in the lower urinary tract dysfunction induced by chronic spinal cord injury in rats. Exp Neurol 2004; 187: 445-454.
19. + channel function and its regulation by protein kinase C pathway in bronchial myocytes from asthmatic rats. Chin Med J 2003; 116: 1799-1803.
20. + channel subtype transcripts in several types of smooth muscles of the rat. J Smooth Muscle Res 2000; 36: 101-115.
21. Hashitani H, Brading AF. Ionic basis for the regulation of spontaneous excitation in detrusor smooth muscle cells of the guinea-pig urinary bladder. Br J Pharmacol 2003; 140: 159-169.