Acetylcholinesterase inhibitor in combination with cognitive training in older adults

Journals of Gerontology - Series B Psychological Sciences and Social Sciences

Volumn 63, Issue 5, 2008, Pages

  Yesavage, Jerome A ^a,b   Friedman, Leah ^b   Ashford, J Wesson ^a,b   Kraemer, Helena C ^b   Mumenthaler, Martin S ^b   Noda, Art ^b   Hoblyn, Jennifer ^b  

^a VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acetylcholinesterase inhibitor; Cognitive training; Donepezil

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITOR; DONEPEZIL; PLACEBO;

ABNORMAL DREAMING; ADULT; AGED; ANOREXIA; ARTICLE; CLINICAL TRIAL; COGNITIVE THERAPY; COMMUNITY LIVING; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DOUBLE BLIND PROCEDURE; DRUG MEGADOSE; DRUG TOLERANCE; FATIGUE; FEMALE; HEADACHE; HUMAN; INSOMNIA; MAJOR CLINICAL STUDY; MALE; MEMORY DISORDER; MUSCLE CRAMP; PAIN; POLLAKISURIA; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SIDE EFFECT; VOLUNTEER; VOMITING; WEIGHT REDUCTION;

EID: 52949118503     PISSN: 10795014     EISSN: None     Source Type: Journal    
DOI: 10.1093/geronb/63.5.P288     Document Type: Article

References (42)

1. American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: Author.
2. Backman, L., Mantyla, T., & Herlitz, A. (1990). The optimization of episodic remembering in old age. In P. B. Baltes & M. M. Baltes (Eds.), Successful aging: Perspectives from the behavioral sciences (pp. 118-163). New York: Cambridge University Press.
3. Ball, K., Berch, D. B., Helmers, K. F., Jobe, J. B., Leveck, M. D., Marsiske, M., et al. (2002). Effects of cognitive training interventions with older adults: A randomized controlled trial. Journal of the American Medical Association, 288, 2271-2281.
4. Bartus, R. T., Dean, R. L., Beer, B., & Lippa, A. S. (1982). The cholinergic hypothesis of geriatric memory dysfunction. Science, 217, 408-414.
5. Bentley, P., Husain, M., & Dolan, R. J. (2004). Effects of cholinergic enhancement on visual stimulation, spatial attention, and spatial working memory. Neuron, 41, 969-982.
6. Bentley, P., Vuilleumier, P., Thiel, C. M., Driver, J., & Dolan, R. J. (2003). Cholinergic enhancement modulates neural correlates of selective attention and emotional processing. Neurolmage, 20, 58-70.
7. Bohnen, N. I., Kaufer, D. I., Hendrickson, R., Ivanco, L. S., Lopresti, B. J., Koeppe, R. A., et al. (2005). Degree of inhibition of cortical acetylcholinesterase activity and cognitive effects by donepezil treatment in Alzheimer's disease. Journal of Neurology, Neurosurgery & Psychiatry, 76, 315-319.
8. Brooks, J. O., Friedman, L., Pearman, A. M., Gray, C., & Yesavage, J. A. (1999). Mnemonic training in older adults: Effects of age, length of training, and type of cognitive pretraining. International Psychogeriatrics, 11, 75-84.
9. Davis, B., & Sadik, K. (2006). Circadian cholinergic rhythms: Implications for cholinesterase inhibitor therapy. Dementia and Geriatric Cognitive Disorders, 21, 20-129.
10. Davis, K. L., Hollister, L. E., Overall, J., Johnson, A., & Train, K. (1976). Physostigmine: Effects on cognition and affect in normal participants. Psychopharmacology, 51, 23-27.
11. Davis, K. L., Mohs, R., Tinklenberg, J. R., Pfefferbaum, A., Hollister, L. E., & Kopell, B. S. (1978). Physostigmine: Improvement of longterm memory processes in normal humans. Science, 201, 272-274.
12. Davidsson, P., Blennow, K., Adreasen, N., Eriksson, B., Minthon, L., & Hesse, C. (2001). Differential increase in cerebrospinal fluid acetylcholinesterase after treatment with acetylcholinesterase inhibitors in patients with Alzheimer's disease. Neuroscience Letters, 300, 157-160.
13. Doody, R. S. (1999). Clinical profile of donepezil in the treatment of Alzheimer's disease. Gerontology, 45(Suppl. 1), 23-32.
14. Folstein, M. F., Folstein, S. E., & McHugh, P. H. (1975). Mini-Mental State: A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12, 189-198.
15. Freo, U., Ricciardi, E., Pietrini, P., Schapiro, M. B., Rapoport, S. I., & Furey, M. L. (2005). Pharmacological modulation of prefrontal cortical activity during a working memory task in young and older humans: A pet study with physostigmine. American Journal of Psychiatry, 162, 2061-2070.
16. Furey, M. L., Pietrini, P., & Haxby, J. V. (2000). Cholinergic enhancement and increased selectivity of perceptual processing during working memory. Science, 290, 2315-2319.
17. Furey, M. L., Pietrini, P., Haxby, J. V., Alexander, G. E., Lee, H. C., VanMeter, J., et al. (1997). Cholinergic stimulation alters performance and task-specific regional cerebral blood flow during working memory. Proceedings of the National Academy of Sciences, 94, 6512-6516.
18. Haug, K. H., Bogen, I. L., Osmundsen, H., Walaas, S. I., & Fonnum, F. (2005). Effects on cholineric markers in rat brain and blood after short and prolonged administration of donepezil. Neurochemical Research, 30, 1511-1520.
19. Hill, R. D., Sheikh, J. I., & Yesavage, J. A. (1988). Pretraining enhances mnemonic training in elderly adults. Experimental Aging Research, 14, 207-211.
20. Hill, R. D., Yesavage, J. A., Sheikh, J., & Friedman, L. (1989). Mental status as a predictor of response to memory training in older adults. Educational Gerontology, 15, 633-639.
21. Hixson, J. E., & Vernier, D. T. (1990). Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with Hhai. Journal of Lipid Research, 31, 545-548.
22. Hulse, J. D., Rogers, S. L., Friedhoff, L. T., Sukovaty, R., & Pedersen, J. E. (1992). A radioenzyme assay of acetylcholinesterase activity in red blood cells and its correlation with l-benzyl-4-[(5,6-dimethoxy-lindanon)-2- yl] methyl piperidine. Pharmacological Research, 9, S228.
23. McGeer, E., & McGeer, P. L. (1976). Age changes in the human for some enzymes associated with metabolism of catecholamines and GABA. In J. M. Ordee & R. R. Brizee (Eds.), Neurohiology of aging (Vol. 389). New York: Raven Press.
24. McKitrick, L. A., Friedman, L. F., Brooks, J. O., Pearman, A., Kraemer, H. C, & Yesavage, J. A. (1999). Predicting response of older adults to mnemonic training: Who will benefit? International Psvchogeriatrics, 11, 289-300.
25. Nurnberger, J. I., Adkins, S., Lahiri, D. K., Mayeda, A., Hu, K., Lewy, A., et al. (2000). Melatonin suppression by light in euthymic bipolar and unipolar patients. Archives of General Psychiatry, 57, 572-579.
26. Parnetti, L., Amici, S., Lanari, A., Romani, C., Antognelli, C., Abdreasen, N., et al. (2002). Cerebrospinal fluid levels of biomarkers and activity of acetylcholinesterase and butyrylcholinesterase in AD patients before and after treatment with different AChE inhibitors. Neurological Sciences, 23, S95-S96.
27. Petersen, R. C., Thomas, R. G., Grundman, M., Bennett, D., Doody, R., Ferris, S., et al. (2005). Vitamin E and donepezil for the treatment of mild cognitive impairment. New England Journal of Medicine, 352, 2379-2388.
28. Rogers, S. L., Doody, R. S., Mohs, R. C., & Friedhoff, L. T. (1998). Donepezil improves cognition and global function in Alzheimer disease: A 15-week, double-blind, placebo-controlled study. Donepezil study group. Archives of Internal Medicine, 158, 1021-1031.
29. Rogers, S. L., & Friedhoff, L. T. (1996). The efficacy and safety of donepezil in patients with Alzheimer's disease: Results of a US multicentre, randomized, double-blind, placebo-controlled trial. The donepezil study group. Dementia, 7, 293-303.
30. Sivan, A. B. (1992). Benton visual retention test. New York: Psychological Corporation.
31. Smith, A. (1991). Symbol digit modalities test. Los Angeles, CA: Western Psychological Services.
32. Stewart, A. L. (1992). Summary and discussion of MOS measures. In A. L. Stewart & J. Ware (Eds.), Measuring functioning and well-being: The medical outcomes study approach (pp. 345-371). Durham, NC: Duke University Press.
33. Verhaeghen, P., Marcoen, A., & Goossens, L. (1992). Improving memory performance in the aged through mnemonic training: A meta-analytic study. Psychology and Aging, 7, 242-251.
34. Wechsler, D. (1987). Wechsler Memory Scale-Revised. San Antonio, TX: Psychological Corporation.
35. Willis, S. L. (1987). Cognitive training and everyday competence. In K. W. Schaie (Ed.), Annual review of gerontology and geriatrics (Vol. 7, pp. 159-188). New York: Springer.
36. Willis, S. L., & Marsiske, M. (1993). Manual for the Everyday Problems Test. Pennsylvania State University, PA: Department of Human Development and Family Studies.
37. Willis, S. L., & Nesselroade, C. S. (1990). Long-term effects of fluid ability training in old-old age. Developmental Psychology, 26, 1-6.
38. Willis, S. L., Tennstedt, S. L., Marsiske, M., Ball, K., Elias, J., Koepke, K. M., et al. (2006). Long-term effects of cognitive training on everyday functional outcomes in older adults. Journal of the American Medical Association, 296, 2805-2814.
39. Yesavage, J. A. (1985). Non-pharmacologic treatments for memory losses with normal aging. American Journal of Psychiatry, 142, 600-605.
40. Yesavage, J. A. (1983). Imagery pretraining and memory training in the elderly. Gerontology, 29, 271-275.
41. Yesavage, J. A., Mumenthaler, M. S., Taylor, J. L., Friedman, L., O'Hara, R., Sheikh, J., et al. (2002). Donepezil and flight simulator performance: Effects on retention of complex skills. Neurology, 59, 123-125.
42. Yesavage, J. A., & Rose, T. L. (1984). Semantic elaboration and the method of loci: A new trip for older learners. Experimental Aging Research, 10, 155-159.