Peptide-polymer biotherapeutic synthesis on novel cross-linked beads with "spatially tunable" and "isolated" functional sites

Biopolymers - Peptide Science Section

Volumn 90, Issue 4, 2008, Pages 512-525

  Jacob, M K ^a   Leena, S ^a   Kumar, K S ^a  

^a RAJIV GANDHI CENTRE FOR BIOTECHNOLOGY   (India)

Author keywords

Amphipathic; Cross linked polymer; Functional site isolated; PEGylation; Peptide

Indexed keywords

AMINES; CHEMICAL REACTIONS; ETHYLENE; ETHYLENE GLYCOL; FREE RADICALS; FUNCTIONAL GROUPS; GLYCOLS; MONOMERS; POLYETHYLENE GLYCOLS; POLYMERS;

AMPHIPATHIC; BIOTHERAPEUTICS; CONVENTIONAL POLYMERS; CROSS LINKERS; CROSS-LINKED BEADS; CROSS-LINKED POLYMER; CROSS-LINKED POLYMERS; ETHYLENE GLYCOLS; FUNCTIONAL SITE ISOLATED; FUNCTIONAL SITES; FUNCTIONALIZATION; OPTIMAL SITE; PEGYLATION; PEPTIDE; SOLID-PHASE SYNTHESIS; SUSPENSION POLYMERIZATIONS;

FREE RADICAL POLYMERIZATION;

3,3' MACROGOL BIS[ 1 ( 4 VINYLPHENOXY)PROPAN 2 OL]; 4 HYDROXYSTYRENE; BACTENECIN; ETHYLENE GLYCOL; INDOLICIDIN; MACROGOL; MACROGOL 1000; MACROGOL 2000; MACROGOL 5000; POLYMER; POLYPEPTIDE ANTIBIOTIC AGENT; POLYSTYRENE DERIVATIVE; TACHYPLESIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BIOASSAY; CARBON NUCLEAR MAGNETIC RESONANCE; CROSS LINKING; DRUG CONJUGATION; DRUG STRUCTURE; DRUG SYNTHESIS; ESCHERICHIA COLI; HEMOLYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFRARED SPECTROSCOPY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR SIZE; MOLECULAR STABILITY; POLYMERIZATION; PSEUDOMONAS AERUGINOSA; SCANNING ELECTRON MICROSCOPY; SEQUENCE ANALYSIS; SOLID PHASE SYNTHESIS; SOLVATION;

ANTIMICROBIAL CATIONIC PEPTIDES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COMBINATORIAL CHEMISTRY TECHNIQUES; CROSS-LINKING REAGENTS; HEMOLYSIS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; MICROSCOPY, ELECTRON, SCANNING; PEPTIDES; POLYETHYLENE GLYCOLS; POLYMERS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

TETRA;

EID: 52949117666     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.20969     Document Type: Article

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