Complement C1q and C8β deficiency in an individual with recurrent bacterial meningitis and adult-onset systemic lupus erythematosus-like illness

Rheumatology

Volumn 47, Issue 10, 2008, Pages 1588-1589

  Pickering, Mathew C ^a   Macor, P ^b   Fish, J ^a   Durigutto, P ^b   Bossi, F ^b   Petry, F ^c   Botto, M ^a   Tedesco, F ^b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF TRIESTE   (Italy)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C4; COMPLEMENT COMPONENT C8B; MICROSOME ANTIBODY; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISOLONE; RO ANTIBODY; THYROXINE; COMPLEMENT COMPONENT C8;

ADULT; ANAMNESIS; BACTERIAL MENINGITIS; BLOOD ANALYSIS; CASE REPORT; CAUCASIAN; COMPLEMENT COMPONENT C1Q DEFICIENCY; COMPLEMENT COMPONENT C8B DEFICIENCY; COMPLEMENT DEFICIENCY; DEHYDRATION; DISEASE DURATION; FEMALE; FEVER; HUMAN; IMMUNOASSAY; IMMUNOSUPPRESSIVE TREATMENT; LIVER BIOPSY; LIVER FUNCTION TEST; MALAISE; MOUTH ULCER; NOTE; NULLIPARA; ONSET AGE; PRIORITY JOURNAL; RECURRENT INFECTION; SYSTEMIC LUPUS ERYTHEMATOSUS; TREATMENT OUTCOME; WEIGHT REDUCTION; IMMUNOLOGY; LETTER; MIDDLE AGED; OPPORTUNISTIC INFECTION; RECURRENT DISEASE;

COMPLEMENT C1Q; COMPLEMENT C8; FEMALE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MENINGITIS, BACTERIAL; MIDDLE AGED; OPPORTUNISTIC INFECTIONS; RECURRENCE;

EID: 52949111018     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/ken289     Document Type: Note

References (8)

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2. Petry F. Molecular basis of hereditary C1q deficiency. Immunobiology 1998; 199:286-94.
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5. Tedesco F, Densen P, Villa MA et al. Two types of dysfunctional eighth component of complement (C8) molecules in C8 deficiency in man. Reconstitution of normal C8 from the mixture of two abnormal C8 molecules. J Clin Invest 1983;71:183-91.
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8. Walport MJ, Davies KA, Botto M. C1q and systemic lupus erythematosus. Immunobiology 1998;199:265-85.