Loss of efficacy during long-term infliximab therapy for sight-threatening childhood uveitis

Rheumatology

Volumn 47, Issue 10, 2008, Pages 1510-1514

  Simonini, Gabriele ^a   Zannin, M E ^b   Caputo, R ^a   Falcini, F ^a   De martino, M ^a   Zulian, F ^b   Cimaz, R ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY HOSPITAL OF PADOVA   (Italy)

Author keywords

Children; Chronic uveitis; Infliximab

Indexed keywords

CYCLOSPORIN A; INFLIXIMAB; METHOTREXATE; PREDNISONE; STEROID;

ADOLESCENT; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BEHCET DISEASE; CHILD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DISEASE EXACERBATION; DRUG EFFICACY; DRUG SAFETY; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; FOLLOW UP; HUMAN; HYPOTENSION; ITALY; JUVENILE RHEUMATOID ARTHRITIS; LEUKOPENIA; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROBABILITY; RASH; RECURRENCE RISK; RELAPSE; REMISSION; RESPIRATORY DISTRESS; SARCOIDOSIS; SIDE EFFECT; SYSTEMIC LUPUS ERYTHEMATOSUS; TREATMENT DURATION; TREATMENT OUTCOME; UVEITIS; VISUAL ACUITY;

ADOLESCENT; ANTI-INFLAMMATORY AGENTS; ANTIBODIES, MONOCLONAL; CHILD; CHILD, PRESCHOOL; CHRONIC DISEASE; DRUG ADMINISTRATION SCHEDULE; DRUG RESISTANCE; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFANT; MALE; PROSPECTIVE STUDIES; RECURRENCE; REMISSION INDUCTION; TREATMENT OUTCOME; TUMOR NECROSIS FACTOR-ALPHA; UVEITIS; VISUAL ACUITY;

EID: 52949107276     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/ken298     Document Type: Article

References (21)

1. Kump LI, Cervantes-Castaneda, RA, Androudi SN et al. Analysis of pediatric uveitis cases at a tertiary referral center. Ophthalmology 2006;112:1287-92.
2. Cunnigham ET. Uveitis in children. Ocul Immunol Inflamm 2000;8:251-61.
3. Levy-Clarke GA, Nussenblatt RB, Smith JA. Management of chronic pediatric uveitis. Curr Opin Ophtalmol 2005;16:281-8.
4. Holland GN, Stiehm ER. Special considerations in the evaluation and management of uveitis in children. Am J Ophthalmol 2003;135:867-78.
5. Suhler EB, Smith J, Werthein MS et al. A prospective trial of infliximab therapy for refractory uveitis. Arch Ophthalmol 2005;123:903-12.
6. Reiff A, Takei S, Saudeghi S et al. Etamecept therapy in children with treatment-resistant uveitis. Arthritis Rheum 2001;44:1411-5.
7. Kahn P, Weiss M, Imundo L, Levy DM. Favorable response to high dose infliximab for refractory childhood uveitis. Opthalmology 2006;113:860-4.
8. Foeldvari I, Nielsen S, Kummerle-Deschner J et al. Tumor necrosis factor-alpha blocker in treatment of juvenile idiopathic arthritis -associated uveitis refractory to second line agents: Results of a multinational survey. J Rheumatol 2007;34: 1146-50.
9. Saurenmann RK, Levin AV, Rose JB et al. Tumor necrosis factor alpha inhibitors in the treatment of childhood uveitis. Rheumatology 2006;45:982-90.
10. Gallagher MJ, Quinones K, Cervantes-Castaneds RA, Yilmaz T, Foster CS. Biologic response modifier therapy for refractory childhood uveitis. Br J Ophthalmol 2007;91:1341-4.
11. Rabinovich E. Use of tumor necrosis factor inhibitors in uveitis, Curr Opinion Rheumatol 2007;19:482-6.
12. Jabs DA, Nussemblatt RB, Rosembaum JT. Standardization of Uveltis Nomenclature (SUN) Working Group. Standardization of uveitis nomenclature for reporting clinical data. Results of the first international workshop. Am J Ophthalmol 2OD5; 140:509-16.
13. Jabs DA. Improving the reporting of clinical case series. Am J Ophthalmol 2005;139:900-5.
14. Rajaraman RT, Kimura Y, Li S et al. Retrospective case review of pediatric patients with uveitis treated with infliximab. Ophthalmology 2006:113.308-14.
15. Tynjala P, Lindhal P, Honkanen V, Lahdenne P, Kotaniemi K. Infliximab and etanercept in the treatment of chronic uveitis associated with refractory juvenile idiopathic arthritis. Ann Rheum Dis 2007;66:548-50.
16. Richards JC, Tay-Keamey ML, Murray K, Manners P. Infliximab for juvenile idiopathic arthritis associated uveitis. Clin Exp Ophthalmol 2005;35:461-8.
17. Sharma SM, Ramanan AV, Riley P, Dick AD. Use of infliximab in juvenile onset rheumatological disease-refractory associated uveitis: Efficacy in joint and ocular disease. Ann Rheum Dis 2007;66:840-1.
18. Ardoin SP, Kredich D, Rabinovich E, Schanberrg LE, Jaffe GJ. Infliximab to treat chronic noninfectious uveitis in children: Retrospective case series with long-term follow-up. Am J Opthalmol 2007:144:844-9.
19. Vazquez-Cobian LB, Flynn T, Lehman TJA, Adalimumab therapy for childhood uveitis. J Pediatr 2006;149:572-5.
20. Biester S, Deuter C, Michels H et al. Adalimumab in the therapy of uveitis in childhood. Br J Ophthalmol 2007;91:319-24.
21. Smith JA, Thompson DJS, Whitcup SM et al. A randomized, placebo, controlled, double-masked clinical trial of etanercept for the treatment of uveitis associated with juvenile idiopathic arthritis. Arthritis Rheum 2005;53:18-23.