Lack of difference in pulmonary absorption of digoxin, a P-glycoprotein substrate, in mdr1a-deficient and mdr1a-competent mice

Journal of Pharmacy and Pharmacology

Volumn 60, Issue 10, 2008, Pages 1305-1310

  Manford, Fergus ^a   Riffo Vasquez, Yanira ^a   Spina, Domenico ^a   Page, Clive P ^a   Hutt, Andrew J ^a   Moore, Vanessa ^b   Johansson, Fredrik ^c   Forbes, Ben ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

^c ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

DIGOXIN; GLYCOPROTEIN P; MDR1A PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; FEMALE; MALE; MOUSE; NONHUMAN; RESPIRATORY EPITHELIUM; TISSUE DISTRIBUTION;

ANIMALS; AREA UNDER CURVE; BRAIN; CARBON RADIOISOTOPES; CARDIOTONIC AGENTS; DIGOXIN; FEMALE; KIDNEY; LIVER; LUNG; MALE; MICE; MICE, KNOCKOUT; MYOCARDIUM; P-GLYCOPROTEINS; RESPIRATORY MUCOSA; TIME FACTORS; TRITIUM;

EID: 52949097208     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp/60.10.0006     Document Type: Article

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