Asymmetric total synthesis of botcinic acid and its derivatives: synthetic revision of the structure of botcinolides

Tetrahedron Letters

Volumn 49, Issue 46, 2008, Pages 6514-6517

  Fukui, Hiroki ^a   Hitomi, Seiichi ^a   Suzuki, Ryo suke ^a   Ikeda, Tatsuhiko ^a   Umezaki, Yuma ^a   Tsuji, Keisuke ^a   Shiina, Isamu ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Botcinic acid; Botcinin; Botcinolide; Structural revision; Total synthesis

Indexed keywords

2 EPIBOTCINOLIDE; 3 O ACETYL 5 O METHYLBOTCINOLIDE; 3 O ACETYLBOTCINIC ACID METHYL ESTER; 4 O METHYLBOTCINOLIDE; BOTCINERIC ACID; BOTCINIC ACID; BOTCINIC ACID METHYL ESTER; BOTCININ E; BOTCINOLIDE; HOMOBOTCINOLIDE; NATURAL PRODUCT; UNCLASSIFIED DRUG;

ARTICLE; ASYMMETRIC SYNTHESIS; CHEMICAL STRUCTURE; DRUG IDENTIFICATION; DRUG STRUCTURE; DRUG SYNTHESIS; STEREOCHEMISTRY;

EID: 52949093876     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2008.08.108     Document Type: Article

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15. +) 425.2146, found 425.2147.
16. +) 407.2040, found 407.2034.
17. * This resonance was observed as a cross peak in HMBC spectrum.
18. +) 439.2308, found 439.2307.
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21. The proton positions in parentheses are numbered according to the botcinin skeleton nomenclature by Nakajima.