Mutations at position 7445 in the precursor of mitochondrial tRNASer(UCN) gene in three maternal Chinese pedigrees with sensorineural hearing loss

Mitochondrion

Volumn 8, Issue 4, 2008, Pages 285-292

  Chen, Jing ^a   Yuan, Huijun ^a   Lu, Jianxin ^b   Liu, Xin ^a   Wang, Guojian ^a   Zhu, Yi ^b   Cheng, Jing ^a   Wang, Xinjian ^c   Han, Bing ^a   Yang, Li ^c   Yang, Shuzhi ^a   Yang, Aifeng ^b   Sun, Qing ^a   Kang, Dongyang ^a   Zhang, Xin ^a   Dai, Pu ^a   Zhai, Suoqiang ^a   Han, Dongyi ^a   Young, Wie Yen ^a   Guan, Min Xin ^c,d  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b WENZHOU MEDICAL UNIVERSITY   (China)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^d UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Chinese; Hearing loss; Mitochondria; Mutation; Precursor; Processing; tRNA

Indexed keywords

ADENINE; CYTOSINE; GLYCINE; LYSINE; MESSENGER RNA; MITOCHONDRIAL DNA; MITOCHONDRIAL RNA; POLYPEPTIDE; RNA PRECURSOR; SERINE; SERINE TRANSFER RNA; THYMINE;

3' UNTRANSLATED REGION; ADOLESCENT; ADULT; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHINESE; CLINICAL ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; DISEASE SEVERITY; DNA POLYMORPHISM; EXTRACHROMOSOMAL INHERITANCE; FAMILY STUDY; FEMALE; GENE MUTATION; GENETIC ANALYSIS; HOMOPLASY; HUMAN; MALE; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; ONSET AGE; PATHOGENESIS; PEDIGREE ANALYSIS; PENETRANCE; PERCEPTION DEAFNESS; POSITION EFFECT; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROCESSING; SEQUENCE ANALYSIS; STOP CODON;

ASIAN CONTINENTAL ANCESTRY GROUP; BASE SEQUENCE; CHINA; DNA MUTATIONAL ANALYSIS; DNA, MITOCHONDRIAL; FEMALE; HEARING LOSS, SENSORINEURAL; HUMANS; PEDIGREE; PENETRANCE; POINT MUTATION; RNA, TRANSFER, SER;

EID: 52749098975     PISSN: 15677249     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mito.2008.05.002     Document Type: Article

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