Revascularization of transplanted islets: Can it be Improved?

Diabetes

Volumn 57, Issue 9, 2008, Pages 2269-2271

  Brissova, Marcela ^a   Powers, Alvin C ^a,b,c  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PLATELET DERIVED GROWTH FACTOR; VASCULOTROPIN A;

ANGIOGENESIS; BONE MARROW; CELL CULTURE; HUMAN; MESENCHYMAL STEM CELL TRANSPLANTATION; NOTE; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; REVASCULARIZATION; TISSUE REGENERATION; ANIMAL; GRAFT SURVIVAL; INSULIN DEPENDENT DIABETES MELLITUS; ISCHEMIA; PANCREAS ISLET; PATHOPHYSIOLOGY; PHYSIOLOGY; POSTOPERATIVE COMPLICATION; REVIEW; VASCULARIZATION;

ANIMALS; DIABETES MELLITUS, TYPE 1; GRAFT SURVIVAL; HUMANS; ISCHEMIA; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; NEOVASCULARIZATION, PHYSIOLOGIC; POSTOPERATIVE COMPLICATIONS;

EID: 52749098107     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db08-0814     Document Type: Note

References (19)

1. Lammert E, Gu G, McLaughlin M, Brown D, Brekken R, Murtaugh LC, Gerber HP, Ferrara N, Melton DA: Role of VEGF-A in vascularization of pancreatic islets. Curr Biol 13:1070-1074, 2003
2. Brissova M, Shostak A, Shiota M, Wiebe PO, Poffenberger G, Kantz J, Chen Z, Carr C, Jerome WG, Chen J, Baldwin HS, Nicholson W, Bader DM, Jetton T, Gannon M, Powers AC: Pancreatic islet production of vascular endothelial growth factor-a is essential for islet vascularization, revascularization, and function. Diabetes 55:2974-2985, 2006
3. Lammert E, Cleaver O, Melton D: Induction of pancreatic differentiation by signals from blood vessels. Science 294:564-567, 2001
4. Edsbagge J, Johansson JK, Esni F, Luo Y, Radice GL, Semb H: Vascular function and sphingosine-1-phosphate regulate development of the dorsal pancreatic mesenchyme. Development 132:1085-1092, 2005
5. Jacquemin P, Yoshitomi H, Kashima Y, Rousseau GG, Lemaigre FP, Zaret KS: An endothelial-mesenchymal relay pathway regulates early phases of pancreas development. Dev Biol 290:189-199, 2006
6. Carlsson PO, Palm F, Andersson A, Liss P: Markedly decreased oxygen tension in transplanted rat pancreatic islets irrespective of the implantation site. Diabetes 50:489-495, 2001
7. Mattsson G, Jansson L, Carlsson PO: Decreased vascular density in mouse pancreatic islets after transplantation. Diabetes 51:1362-1366, 2002
8. Brissova M, Fowler MJ, Wiebe P, Shostak A, Shiota M, Radhika A, Lin PC, Gannon M, Powers AC: Intra-islet endothelial cells contribute to revascularization of transplanted pancreatic islets. Diabetes 53:1318-1325, 2004
9. Nyqvist D, Kohler M, Wahlstedt H, Berggren PO: Donor islet endothelial cells participate in formation of functional vessels within pancreatic islet grafts. Diabetes 54:2287-2293, 2005
10. Contreras JL, Smyth CA, Eckstein C, Bilbao G, Thompson JA, Young CJ, Eckhoff DE: Peripheral mobilization of recipient bone marrow-derived endo-thelial progenitor cells enhances pancreatic islet revascularization and engraftment after intraportal transplantation. Surgery 134:390-398, 2003
11. Miller R, Cirulli V, Diaferia GR, Ninniri S, Hardiman G, Torbett BE, Benezra R, Crisa L: Switching-on survival and repair response programs in islet transplants by bone marrow-derived vasculogenic cells. Diabetes 57:24022412, 2008
12. Lai Y, Schneider D, Kidszun A, Hauck-Schmalenberger I, Breier G, Brandhorst D, Brandhorst H, Iken M, Brendel MD, Bretzel RG, Linn T: Vascular endothelial growth factor increases functional beta-cell mass by improvement of angiogenesis of isolated human and murine pancreatic islets. Transplantation 79:1530-1536, 2005
13. Olerud J, Johansson M, Lawler J, Welsh N, Carlsson PO: Improved vascular engraftment and graft function following inhibition of the angiostatic factor thrombospondin-1 in mouse pancreatic islets. Diabetes 57:1870-1877, 2008
14. Su D, Zhang N, He J, Qu S, Slusher S, Bottino R, Bertera S, Bromberg J, Dong HH: Angiopoietin-1 production in islets improves islet engraftment and protects islets from cytokine-induced apoptosis. Diabetes 56:2274-2283, 2007
15. Zhang N, Richter A, Suriawinata J, Harbaran S, Altomonte J, Cong L, Zhang H, Song K, Meseck M, Bromberg J, Dong H: Elevated vascular endothelial growth factor production in islets improves islet graft vascularization. Diabetes 53:963-970, 2004
16. Johansson U, Rasmusson I, Niclou SP, Forslund N, Gustavsson L, Nilsson B, Korsgren O, Magnusson PU: Formation of composite endothelial cell-mesenchymal stem cell-islets; a novel approach to promote islet revascularization. Diabetes 57:2393-2401, 2008
17. Ball SG, Shuttleworth CA, Kielty CM: Mesenchymal stem cells and neovascularization: role of platelet-derived growth factor receptors. J Cell Mol Med 11:1012-1030, 2007
18. Brooke G, Cook M, Blair C, Han R, Heazlewood C, Jones B, Kambouris M, Kollar K, McTaggart S, Pelekanos R, Rice A, Rossetti T, Atkinson K: Therapeutic applications of mesenchymal stromal cells. Semin Cell Dev Biol 18:846-858, 2007
19. Kumar S, Chanda D, Ponnazhagan S: Therapeutic potential of genetically modified mesenchymal stem cells. Gene Ther 15:711-715, 2008