Progress in research on triterpenoid saponins of Platycodon grandiflorum (Jacp.) A. DC.

Chinese Pharmaceutical Journal

Volumn 43, Issue 11, 2008, Pages 801-804

  Guo, Wen Jie ^a   Xu, Xu Dong ^a   Wei, Jian He ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

PLATYCODIN; PLATYCODON GRANDIFLORUM EXTRACT; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; NONHUMAN; PHYTOCHEMISTRY; PLATYCODON; RAT; STRUCTURE ANALYSIS;

EID: 52749097353     PISSN: 10012494     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. GAO W Y, LI Z L. Proceeding of modern research on Platycodon grandiflorum A. DC[J]. Prim J Chin Mat Med, 1996,10(2):48-49.
2. MAO Y L. Clinical value of Platycodon grandiflorum A. DC[ J]. China Pharm, 2001,10(10):65.
3. DING Y Q. Effect and application of Platycodon grandiflorum A. DC[J]. China J Chin Mater Med, 1998,23(5):308-309.
4. HE M L, CHENG X W, CHEN J K, et al. The saponins in Platycodon grandiflorum A. DC and their analysis[J]. Tradit Chin Drug Res Clin Pharmacol, 2005,16(6):457-459.
5. TADA A, KANEIWA Y, SHOJI J, et al. Studies on the saponins of the roots of Platycodon grandiflorum A. DC[J]. Chem Pharm Bull, 1975,23(11):2965-2972.
6. KONISHI T, TADA A, SHOJI J, et al. The structures of platycodin A and C monoacetylated saponins of the roots of Platycodon grandiflorum A. DC[J]. Chem Pharm Bull, 1978,26(1):668-670.
7. 3 platyconic acid A, and their derivatives, saponins isolated from roots of Platycodon grandiflorum A. DC determined by carbon-13 NMR spectroscopy[J]. Chem Lett, 1978,26(2):719-722.
8. 2 and their monacetates saponins isolated from Platycodon grandiflorum A. DC determined by carbon-13 nuclear magnetic resonance spectroscopy[J]. Chem Pharm Bull, 1978,26(2):674-677.
9. 3 isolated from the root of Platycodon grandflorum modulate the production of nitric oxide and secretion of TNF-α in activated RAW 264. 7 cells[J]. Inter Immunopharm, 2004,(4):1039-1049.
10. NIKAIDO T, KOIKE K, MITSUNAGA K, et al. Two new triterpenoid saponins from Platycodon grandiflorum[J]. Chem Pharm Bull, 1999,47(6):903-904.
11. HE Z D, QIAO C F, HAN Q B, et al. New triterpenoid saponins from the roots of Platycodon grandflorum[J]. Tetrahedron, 2005,61(8):2211-2215.
12. AKIYAMA T, TANAKA O, SHIBATA S. Chemical studies on the oriental plant drugs. XXXII. sapogenins from the roots of Platycodon grandiflorum A. DC[J]. Chem Pharm Bull, 1972,20(9):1957-1961.
13. KUBOTA T, KITATANI H, HINOH H. Structure of platycogenic acids A, B and C further triterpenoid constituents of Platycodon grandiflorum[J]. Chem Soc D, 1969,22(22):1313-1314.
14. ISHII H, TORI K, TOZYO T, et al. Structures of prosapogenins from roots of Platycodon grandiflorum determined by carbon-13 and hydrogen-1 nuclear magnetic resonance spectroscopy[J]. Chem Pharm Bull, 1978,26(1):671-673.
15. ISHII H, TORI K, TOZYO T, et al. Saponins from roots of Platycodon grandflorum A. DC part 2 isolation and structure of new triterpene glycosides[J]. J Chem Soc Perkin Trans I, 1984,10:661-668.
16. ISHII H, TORI K, TOZYO T, et al. Saponins from roots of Platycodon grandiflorum part 1 structure of prosapogenins[J]. J Chem Soc Perkin Trans I, 1981,719:1928-1933.
17. AKIYAMA T, TANAKA O, SHIBATA S. Chemical studies on the oriental plant drugs. X X X. Sapogenins of the roots of Platycodon grandiflorum A. DC(1) isolation of the sapogenins and the stereochemistry of polygalacic acid[J]. Chem Pharm Bull, 1972,20(9):1945-1951.
18. NIKAIDO T, KOIKE K, MITSUNAGA K, et al. Triterpenoid saponins from root of Platycodon grandiflorum[J]. Nat Med, 1998,52(1):54-59.
19. FU W W, SHIMIZU N, DOU D Q, et al. Five new triterpenoid saponins from the roots of Platycodon grandiflorum[J]. Chem Pharm Bull, 2006,54(4):557-560.
20. KIM Y S, KIM J S, CHOI S U, et al. Isolation of a new saponin and cytotoxic effect of saponins from the root of Platycodon grandiflorum on human tumor cell lines[J]. Planta Med, 2005,71(6):566-568.
21. YANG X W, LIU M Y, Y Q, et al. Method of preparing prosapogenins of Ptatycodon grandiflorum[J]. J Jilin Agric Univ, 2002,24(1):64-65.
22. LI W, XIANG L, ZHANG J, et al. A new triterpenoid saponin from the roots of Platycodon grandiflorum[J]. Chin Chem Lett, 2007,18(3):306-308.
23. YOON Y D, HAN S B, KANG J S, et al. Toll-like receptor 4-dependent activation of macrophages by polysaccharide isolated from the radix of Platycodon grandiflorum[J]. Int Immunopharm, 2003,3(13-14):1873- 1882.
24. DING C J, WEI Y D, AN Z Y, et al. Analysis of chemical constituents of volatile oil from Platycodon grandiflorum[J]. J Norman Bethune Unit Med Sci, 1996,22(5):471-472.
25. JI C. Health products Platycodon grandiflorum[J]. China Health Food, 2005,10(1):6-7.
26. ZHENG H Z, DONG Z H, SE J. Modern Chinese Medicine Research and Application (4) [M]. Beijing: Academy Press, 1998:3627.
27. SONG Y, QI Y. Pharmacological progress on Platycodon grandiflorum[J]. China Pharm, 2006,179(2):140-141.
28. 2 production by platycodin D isolated from the root of Platycodon grandiflorum[J]. Planta Med, 2001,67(4):362-364.
29. GE J F, LI J, YAO H W. Proceeding of the study on the immunologic pathogenesis of chronic bronchitis[J]. Anhui Med Pharm J, 2003,7(3):163-165.
30. 3 increase airway mucin releade in vivo in vitro rats and hamsters[J]. Planta Med, 2002,68(3):221-225.
31. LEE KJ, KIM J Y, JUNG K S, et al. Protective effects of Platycodon grandiflorum on the progress of carbon tetrachloride-induced hepatotoxicity[J]. Food Chem Toxicol, 2004,27(12):1238-1244.
32. LEE K J, YOU H J , PARK S J, et al. Hepatoprotective effects of Platycodon grandiflorum on acetaminophen-induced liver damage in mice[J]. Cancer Lett, 2001,174(1):73-81.
33. KIM K S, SEO E K, LEE Y C, et al. Effect of dietary Platyc odon grandiflorum on the improvement of insulin resistance in obese Zucker rats[J]. J Nutr Biochem, 2000,11(9):420-424.
34. ADHID A, MELVIN B. Simple liquid-liquid partition system for isolation of labelled ohic acid from mixture with glycosides[ J]. J Lipid Res, 1969,10(3):341-344.
35. XU B J, ZHENG Y N, HAN L K, et al. Study on fat metabolism of Platycodon grandiflorum[J]. J Dalian Univ, 2000,21(4):77-79.
36. GAO Y F, CHEN C, ZHANG H Y, et al. Effect of total saponins of Platycodon grandiflorum on hyperlipidemia in rats[J]. Chin Herb Med, 2000,31(10):764-767.
37. ZHENG Y N, LIU K Y, XU B J, et al. Study on the anti-obesity mechanism of Platycodon grandiflorum[J]. J Jilin Agric Univ, 2002,24(6):42-44.
38. KIM K S, EZAKI O, IKEMOTO S, et al. Effects of Platycodon grandiflorum feeding on serum and liver lipid concentrations in rats with diet-induced hyperlipidemia[J]. J Nutr Sci Vitaminol (Tokyo), 1995,41(4):485-491.
39. CHOI S S, HAN E J, LEE T H, et al. Antinociceptive mechanisms of platycodin D administered intracerebroventricularly in the mouse[J]. Planta Med, 2002,68(9):794-798.
40. GONG X J, CHEN L R, SUN Y S, et al. Study on the tyrosine inhibition active components in Platycodon grandiflorum[J]. J Chin Med Mat, 2004,27(4):257-258.
41. HUANG B B, FAN M W, YANG X L, et al. Inhibition of Platycodon grandiflorum, glycyrrhiza and their compound to oral pathogens in vitro[J]. J Pract Stomatol, 2003,19(2):148-150.