Effects of astragaloside IV on cardiac collagen content in rats with acute myocardial infarction and its mechanisms

Chinese Pharmaceutical Journal

Volumn 43, Issue 11, 2008, Pages 833-837

  Lin, Yi ^a   Ning, Xian Feng ^a   Yu, Wen ^b   Li, Zi Pu ^a  

^a QINGDAO UNIVERSITY MEDICAL COLLEGE   (China)

^b Eighth People's Hospital of Qingdao City   (China)

Author keywords

Astragaloside IV; Collagen; Myocardial infarction; Rats

Indexed keywords

ANGIOTENSIN II; ASTRAGALOSIDE IV; COLLAGEN; ENDOTHELIN; GELATINASE A; GELATINASE B; PROCOLLAGEN; PROCOLLAGEN TYPE 3 AMINOPROPEPTIDE; TISSUE INHIBITOR OF METALLOPROTEINASE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLLAGEN DEGRADATION; COLLAGEN SYNTHESIS; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORONARY ARTERY; HEART INFARCTION; IMMUNOHISTOCHEMISTRY; NONHUMAN; PROTEIN EXPRESSION; RAT;

EID: 52749091544     PISSN: 10012494     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Ch. P (2005) Vol I [S]. 2005:212-213.
2. FISHBEIN M C, MACLEAN D, MAROKO P R. Experimental myocardial infarction in the rat [J]. Am J Pathol, 1978, 90(1):57-70.
3. ZHOU J, LI D Y, CHEN Q Z. Myocardial hypertrophy in pressure overload rats and the preventive effects of losartan and lisinopril [J]. Chin J Clin Rehabilit, 2005, 9(19):35-37.
4. WU X R, YANG M, LI Y G. Treatment effects of bone marrow stem cell mobilization on rat ischemic myocardium [J]. Chin J Immunol, 2004, 20(7):471-474.
5. WANG Z T, WANG S R, ZHAO M J, et al. Comparative study on effect of recipe for activating blood circulation and replenishing qi on left ventricular remodeling in rats with left heart failure after myocardial infarction [J]. Chin J Integr Tradit West Med, 2002, 22(5):376-378.
6. TANG Z Z. Study on reversal effects and mechamism of Salvia miltiorrhiza Bge on myocardial fibrosis in spontaneously hypertensive rats [J]. Acta Med Univ Sci Technol Huazhong, 2002, 31(3):292-294.
7. LI Z P, CAO Q. Effects of astragaloside IV on myocardial calcium transport and cardiac function in ischemic rats [J]. Acta Pharmacol Sin, 2002, 23(10):898-904.
8. LOU Y H, BI Q. Effect of austagalus rnembranaceus injection on serum procollagen peptides in patients with viral myocarditis [J]. Zhejiang J Integr Tradit Chin Western Med, 2004, 14(8):468-469.
9. LOPES J D, GOMES R A, HIAL V, et al. Correlations between the collagen content of the human left ventricular myocardium, measured by biochemical and morphometric methods [J]. Arq Bras Cardiol, 2002, 79(1):10-19.
10. LOMBARDI R, BETOCCHI S, LOSI M A, et al. Myocardial collagen turnover in hypertrophic cardiomyopathy [J]. Circulation, 2003, 108(12):1455-1460.
11. LI Z P, CAO Q, PANG X Y. Dosage and time effects of astragaloside IV on myocardial collagen and cardiac function of ischemic rats [J]. Chin J Clin Rehabilit, 2005, 9(23):207-209.
12. HE X L, CHEN Y P, DENG Y Y, et al. Influence of " Compound Huangqi Mixture" on Col-IV and MMP-2/TIMP-2 in early DN rats [J]. Shanghai J Tradit Chin Med, 2003, 37(6):51-54.
13. KATWA L C. Cardiac myofibroblasts isolated from the site of myocardial infarction express endothelin de novo [J]. Am J Physiol Heart Circ Physiol, 2003, 285(3):H1132-1139.
14. AMMARGULLAT F, LAROUCHE I, SCHIFFRIN E L. Myocardial fibrosis in DOCA-salt hypertensive rats. Effects of endothelin ETA receptor antagonism [J]. Circulation, 2001, 103:319-324.