Sleep apnoea: Time to consider clock genes

European Respiratory Journal

Volumn 32, Issue 1, 2008, Pages 1-2

  Andreas, S ^a,c   Eichele, G ^b  

^a Specialist Clinic for Lung Diseases   (Germany)

^b MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; C REACTIVE PROTEIN; GLUCOCORTICOID; INTERLEUKIN 6; NORADRENALIN; PER1 PROTEIN;

ASTHMA; CARDIOVASCULAR DISEASE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CIRCADIAN RHYTHM; DISEASE ASSOCIATION; EDITORIAL; GENE ACTIVATION; GENE EXPRESSION; HUMAN; NEUROGRAPHY; NONHUMAN; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; SLEEP APNEA SYNDROME; SLEEP WAKING CYCLE; ANIMAL; GENETICS; MOUSE; NOTE; SLEEP DISORDER;

ANIMALS; CHRONOBIOLOGY DISORDERS; CIRCADIAN RHYTHM; HUMANS; MICE; SLEEP APNEA SYNDROMES;

EID: 52749084164     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00056308     Document Type: Editorial

References (17)

1. Albrecht U. Invited review: regulation of mammalian circadian clock genes. J Appl Physiol 2002; 92: 1348-1355.
2. Burioka N, Koyanagi S, Endo M, et al. Clock gene dysfunction in patients with obstructive sleep apnoea syndrome. Eur Respir J 2008; 32: 105-112.
3. Burioka N, Fukuoka Y, Takata M, et al. Circadian rhythms in the CNS and peripheral clock disorders: function of clock genes: influence of medication for bronchial asthma on circadian gene. J Pharmacol Sci 2007; 103: 144-149.
4. Warnecke M, Oster H, Revelli JP, Alvarez-Bolado G, Eichele G. Abnormal development of the locus coeruleus in Ear2(Nr2f6)-deficient mice impairs the functionality of the forebrain clock and affects nociception. Genes Dev 2005; 19: 614-625.
5. Hedner J, Darpo B, Ejnell H, Carlson J, Caidahl K. Reduction in sympathetic activity after long-term CPAP treatment in sleep apnoea: cardiovascular implications. Eur Respir J 1995; 8: 222-229.
6. Coy TV, Dimsdale JE, Ancoli-Israel S, Clausen J. Sleep apnoea and sympathetic nervous system activity: a review. J Sleep Res 1996; 5: 42-50.
7. McNicholas WT, Bonsigore MR. Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities. Eur Respir J 2007; 29: 156-178.
8. Yumino D, Bradley TD. Pathogenesis of atherosclerosis: is obstructive sleep apnea the new kid on the block? Am J Respir Crit Care Med 2007; 176: 634-635.
9. Lüthje L, Andreas S. Obstructive sleep apnea and coronary artery disease. Sleep Medicine Review 2008; 12: 19-31.
10. Young ME. The circadian clock within the heart: potential influence on myocardial gene expression, metabolism, and function. Am J Physiol Heart Circ Physiol 2006; 290: H1-H16.
11. Oishi K, Kasamatsu M, Ishida N. Gene- and tissue-specific alterations of circadian clock gene expression in streptozotocin-induced diabetic mice under restricted feeding. Biochem Biophys Res Commun 2004; 317: 330-334.
12. Turek FW, Joshu C, Kohsaka A, et al. Obesity and metabolic syndrome in circadian clock mutant mice. Science 2005; 308: 1043-1045.
13. Giles TL, Lasserson TJ, Smith BJ, White J, Wright J, Cates CJ. Continuous positive airways pressure for obstructive sleep apnoea in adults. Cochrane Database Syst Rev 2006; 3: CD001106.
14. Turek FW. From circadian rhythms to clock genes in depression. Int Clin Psychopharmacol 2007; 22: Suppl. 2, S1-S8.
15. Ebisawa T. Circadian rhythms in the CNS and peripheral clock disorders: human sleep disorders and clock genes. J Pharmacol Sci 2007; 103: 150-154.
16. Raupach T, Bahr F, Herrmann P, et al. Slow breathing reduces sympathoexcitation in chronic obstructive pulmonary disease. Eur Respir J 2008; [Epub ahead of print PMID: 18385175].
17. Andreas S, Anker SD, Scanlon PD, Somers VK. Neurohumoral activation as a link to systemic manifestation of chronic lung disease. Chest 2005; 128: 3618-3624.