-
2
-
-
33847414203
-
Ten years of highly active antiretroviral therapy for HIV infection
-
Chen LFLF, Hoy JJ, Lewin SRSR: Ten years of highly active antiretroviral therapy for HIV infection. Med. J. Aust. 186, 146-151 (2007).
-
(2007)
Med. J. Aust
, vol.186
, pp. 146-151
-
-
Chen, L.F.L.F.1
Hoy, J.J.2
Lewin, S.R.S.R.3
-
3
-
-
33750615911
-
The pathology induced by highly active antiretroviral therapy against human immunodeficiency virus: An update
-
Hofman P, Nelson AM: The pathology induced by highly active antiretroviral therapy against human immunodeficiency virus: an update. Curr. Med. Chem. 13, 3121-3132 (2006).
-
(2006)
Curr. Med. Chem
, vol.13
, pp. 3121-3132
-
-
Hofman, P.1
Nelson, A.M.2
-
5
-
-
52649176046
-
Tracking funding for preventive HIV vaccine research & development: Estimates of annual investments and expenditures 2000-2005
-
Lamourelle G, Harrison P, Rowley J, Warren M: Tracking funding for preventive HIV vaccine research & development: estimates of annual investments and expenditures 2000-2005. International AIDS Vaccine Initiative 1-21 (2005).
-
(2005)
International AIDS Vaccine Initiative
, pp. 1-21
-
-
Lamourelle, G.1
Harrison, P.2
Rowley, J.3
Warren, M.4
-
6
-
-
34347329085
-
Scientific and policy challenges to development of an AIDS vaccine
-
Berkley SF, Koff WC: Scientific and policy challenges to development of an AIDS vaccine. Lancet 370, 94-101 (2007).
-
(2007)
Lancet
, vol.370
, pp. 94-101
-
-
Berkley, S.F.1
Koff, W.C.2
-
7
-
-
35148818748
-
AIDS research: Promising AIDS vaccine's failure leaves field reeling
-
Cohen J: AIDS research: promising AIDS vaccine's failure leaves field reeling. Science 318, 28-29 (2007).
-
(2007)
Science
, vol.318
, pp. 28-29
-
-
Cohen, J.1
-
8
-
-
33745646047
-
Gene-based immunotherapy for human immunodeficiency virus infection and acquired immunodeficiency syndrome
-
Dropulic B, June CH: Gene-based immunotherapy for human immunodeficiency virus infection and acquired immunodeficiency syndrome. Hum. Gene Ther. 17, 577-588 (2006).
-
(2006)
Hum. Gene Ther
, vol.17
, pp. 577-588
-
-
Dropulic, B.1
June, C.H.2
-
9
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC: Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806-811 (1998).
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
10
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T: Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494-498 (2001).
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
11
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee Y, Ahn C, Han JJ et al.: The nuclear RNase III Drosha initiates microRNA processing. Nature 425, 415-419 (2003).
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.J.3
-
12
-
-
0347988235
-
Nuclear export of microRNA precursors
-
Lund E, Guttinger S, Calado A, Dahlberg JE, Kutay U: Nuclear export of microRNA precursors. Science 303, 95-98 (2004).
-
(2004)
Science
, vol.303
, pp. 95-98
-
-
Lund, E.1
Guttinger, S.2
Calado, A.3
Dahlberg, J.E.4
Kutay, U.5
-
13
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein E, Caudy AA, Hammond SM, Hannon GJ: Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409, 363-366 (2001).
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
14
-
-
23644433363
-
TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
-
Chendrimada TP, Gregory RI, Kumaraswamy E et al.: TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature 436, 740-744 (2005).
-
(2005)
Nature
, vol.436
, pp. 740-744
-
-
Chendrimada, T.P.1
Gregory, R.I.2
Kumaraswamy, E.3
-
15
-
-
32544460452
-
The role of PACT in the RNA silencing pathway
-
Lee Y, Hur I, Park S-Y, Kim Y-K, Suh MR, Kim VN: The role of PACT in the RNA silencing pathway. EMBO J. 25, 522-632 (2006).
-
(2006)
EMBO J
, vol.25
, pp. 522-632
-
-
Lee, Y.1
Hur, I.2
Park, S.-Y.3
Kim, Y.-K.4
Suh, M.R.5
Kim, V.N.6
-
16
-
-
0035839109
-
Argonaute2, a link between genetic and biochemical analyses of RNAi
-
Hammond SM, Boettcher S, Caudy AA, Kobayashi R, Hannon GJ: Argonaute2, a link between genetic and biochemical analyses of RNAi. Science 293, 1146-1150 (2001).
-
(2001)
Science
, vol.293
, pp. 1146-1150
-
-
Hammond, S.M.1
Boettcher, S.2
Caudy, A.A.3
Kobayashi, R.4
Hannon, G.J.5
-
17
-
-
4444368187
-
Argonaute2 is the catalytic engine of mammalian RNAi
-
Liu JD, Carmell MA, Rivas FV et al.: Argonaute2 is the catalytic engine of mammalian RNAi. Science 305, 1437-1441 (2004).
-
(2004)
Science
, vol.305
, pp. 1437-1441
-
-
Liu, J.D.1
Carmell, M.A.2
Rivas, F.V.3
-
18
-
-
3242736704
-
Human argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs
-
Meister G, Landthaler M, Patkaniowska A, Dorsett Y, Teng G, Tuschl T: Human argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. Mol. Cell 15, 185-197 (2004).
-
(2004)
Mol. Cell
, vol.15
, pp. 185-197
-
-
Meister, G.1
Landthaler, M.2
Patkaniowska, A.3
Dorsett, Y.4
Teng, G.5
Tuschl, T.6
-
19
-
-
27744506761
-
Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation
-
Rand TA, Petersen S, Du F, Wang X: Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation. Cell 123, 621-629 (2005).
-
(2005)
Cell
, vol.123
, pp. 621-629
-
-
Rand, T.A.1
Petersen, S.2
Du, F.3
Wang, X.4
-
20
-
-
4444302947
-
Crystal structure of argonaute and its implications for RISC slicer activity
-
Song J-J, Smith SK, Hannon GJ, Joshua-Tor L: Crystal structure of argonaute and its implications for RISC slicer activity. Science 305, 1434-1437 (2004).
-
(2004)
Science
, vol.305
, pp. 1434-1437
-
-
Song, J.-J.1
Smith, S.K.2
Hannon, G.J.3
Joshua-Tor, L.4
-
21
-
-
27744590896
-
Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes
-
Matranga C, Tomari Y, Shin C, Bartel DP, Zamore PD: Passenger-strand cleavage facilitates assembly of siRNA into Ago2-containing RNAi enzyme complexes. Cell 123, 607-620 (2005).
-
(2005)
Cell
, vol.123
, pp. 607-620
-
-
Matranga, C.1
Tomari, Y.2
Shin, C.3
Bartel, D.P.4
Zamore, P.D.5
-
22
-
-
4644309196
-
The functions of animal microRNAs
-
Ambros V: The functions of animal microRNAs, Nature 431, 350-355 (2004).
-
(2004)
Nature
, vol.431
, pp. 350-355
-
-
Ambros, V.1
-
23
-
-
1842478962
-
Control of HIV-1 replication by RNA interference
-
Lee NS, Rossi JJ: Control of HIV-1 replication by RNA interference. Virus Res. 102, 53-58 (2004).
-
(2004)
Virus Res
, vol.102
, pp. 53-58
-
-
Lee, N.S.1
Rossi, J.J.2
-
24
-
-
0037173610
-
Modulation of HIV-1 replication by RNA interference
-
Jacque JM, Triques K, Stevenson M: Modulation of HIV-1 replication by RNA interference. Nature 418, 435-438 (2002).
-
(2002)
Nature
, vol.418
, pp. 435-438
-
-
Jacque, J.M.1
Triques, K.2
Stevenson, M.3
-
25
-
-
33748978456
-
The virion-associated incoming HIV-1 RNA genome is not targeted by RNA interference
-
Westerhout E, ter Brake O, Berkhout B: The virion-associated incoming HIV-1 RNA genome is not targeted by RNA interference. Retrovirology 3, 57 (2006).
-
(2006)
Retrovirology
, vol.3
, pp. 57
-
-
Westerhout, E.1
ter Brake, O.2
Berkhout, B.3
-
26
-
-
0036839458
-
Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference
-
Capodici J, Kariko K, Weissman D: Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference. J. Immunol. 169, 5196-5201 (2002).
-
(2002)
J. Immunol
, vol.169
, pp. 5196-5201
-
-
Capodici, J.1
Kariko, K.2
Weissman, D.3
-
27
-
-
0037031148
-
Inhibition of retroviral pathogenesis by RNA interference
-
Hu W-Y, Myers CP, Kilzer JM, Pfaff SL, Bushman FD: Inhibition of retroviral pathogenesis by RNA interference. Curr. Biol. 12, 1301-1311 (2002).
-
(2002)
Curr. Biol
, vol.12
, pp. 1301-1311
-
-
Hu, W.-Y.1
Myers, C.P.2
Kilzer, J.M.3
Pfaff, S.L.4
Bushman, F.D.5
-
28
-
-
0036891843
-
RNA interference directed agains viral and cellular targets inhibits human immunodeficiency virus type 1 replication
-
Surabhi RM, Gaynor RB: RNA interference directed agains viral and cellular targets inhibits human immunodeficiency virus type 1 replication. J. Virol. 76, 12963-12973 (2002).
-
(2002)
J. Virol
, vol.76
, pp. 12963-12973
-
-
Surabhi, R.M.1
Gaynor, R.B.2
-
29
-
-
0036721314
-
Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference
-
Coburn GA, Cullen BR: Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference. J. Virol. 76, 9225-9231 (2002).
-
(2002)
J. Virol
, vol.76
, pp. 9225-9231
-
-
Coburn, G.A.1
Cullen, B.R.2
-
30
-
-
27744453385
-
Inhibition of HIV-1 replication by siRNA targeting conserved regions of gag/pol
-
Morris KV, Chung CH, Witke W, Looney DJ: Inhibition of HIV-1 replication by siRNA targeting conserved regions of gag/pol. RNA Biol. 2, 17-20 (2005).
-
(2005)
RNA Biol
, vol.2
, pp. 17-20
-
-
Morris, K.V.1
Chung, C.H.2
Witke, W.3
Looney, D.J.4
-
31
-
-
0036066508
-
siRNA-directed inhibition of HIV-1 infection
-
Novina CD, Murray MF, Dykxhoorn DM et al.: siRNA-directed inhibition of HIV-1 infection. Nat. Med. 8, 681-686 (2002).
-
(2002)
Nat. Med
, vol.8
, pp. 681-686
-
-
Novina, C.D.1
Murray, M.F.2
Dykxhoorn, D.M.3
-
32
-
-
0036256430
-
Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells
-
Lee NS, Dohjima T, Bauer G et al.: Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat. Biotechnol. 20, 500-505 (2002).
-
(2002)
Nat. Biotechnol
, vol.20
, pp. 500-505
-
-
Lee, N.S.1
Dohjima, T.2
Bauer, G.3
-
33
-
-
0142124143
-
Human immunodeficiency virus type 1 escape from RNA interference
-
Boden D, Pusch O, Lee F, Tucker L, Ramratnam B: Human immunodeficiency virus type 1 escape from RNA interference. J. Virol. 77, 11531-11535 (2003).
-
(2003)
J. Virol
, vol.77
, pp. 11531-11535
-
-
Boden, D.1
Pusch, O.2
Lee, F.3
Tucker, L.4
Ramratnam, B.5
-
34
-
-
1242319384
-
Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition
-
Das AT, Brummelkamp TR, Westerhout EM et al.: Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition. J. Virol. 78, 2601-2605 (2004).
-
(2004)
J. Virol
, vol.78
, pp. 2601-2605
-
-
Das, A.T.1
Brummelkamp, T.R.2
Westerhout, E.M.3
-
35
-
-
13844320402
-
HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome
-
Westerhout EM, Ooms M, Vink M, Das AT, Berkhout B: HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome. Nucleic Acids Res. 33, 796-804 (2005).
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 796-804
-
-
Westerhout, E.M.1
Ooms, M.2
Vink, M.3
Das, A.T.4
Berkhout, B.5
-
36
-
-
33748850724
-
Inhibition of human immunodeficiency virus type 1 by RNA interference using long-hairpin RNA
-
Konstantinova P, de Vries W, Haasnoot J, ter Brake O, de Haan P, Berkhout B: Inhibition of human immunodeficiency virus type 1 by RNA interference using long-hairpin RNA. Gene Ther. 13, 1403-1413 (2006).
-
(2006)
Gene Ther
, vol.13
, pp. 1403-1413
-
-
Konstantinova, P.1
de Vries, W.2
Haasnoot, J.3
ter Brake, O.4
de Haan, P.5
Berkhout, B.6
-
37
-
-
29244433509
-
Escape from the interferon response associated with RNA interference using vectors that encode long modified hairpin-RNA
-
Akashi H, Miyagishi M, Yokota T et al.: Escape from the interferon response associated with RNA interference using vectors that encode long modified hairpin-RNA. Mol. Biosyst. 1, 382-390 (2005).
-
(2005)
Mol. Biosyst
, vol.1
, pp. 382-390
-
-
Akashi, H.1
Miyagishi, M.2
Yokota, T.3
-
38
-
-
37549055424
-
The inhibitory efficacy of RNA POL III-expressed long hairpin RNAs targeted to untranslated regions of the HIV-15′ long terminal repeat
-
Barichievy S, Saayman S, von Elje KJ, Morris KV, Arbuthnot P, Weinberg MS: The inhibitory efficacy of RNA POL III-expressed long hairpin RNAs targeted to untranslated regions of the HIV-15′ long terminal repeat. Oligonucleotides 17, 419-432 (2007).
-
(2007)
Oligonucleotides
, vol.17
, pp. 419-432
-
-
Barichievy, S.1
Saayman, S.2
von Elje, K.J.3
Morris, K.V.4
Arbuthnot, P.5
Weinberg, M.S.6
-
39
-
-
34848814237
-
Design of extended short hairpin RNAs for HIV-1 inhibition
-
Liu YP, Haasnoot J, Berkhout B: Design of extended short hairpin RNAs for HIV-1 inhibition. Nucleic Acids Res. 35, 5683-5693 (2007).
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 5683-5693
-
-
Liu, Y.P.1
Haasnoot, J.2
Berkhout, B.3
-
40
-
-
37549037041
-
Expression of long anti-HIV-1 hairpin RNAs for the generation of multiple siRNAs: Advantages and limitations
-
Sano M, Li H, Nakanishi M, Rossi JJ: Expression of long anti-HIV-1 hairpin RNAs for the generation of multiple siRNAs: advantages and limitations. Mol. Ther. 16 170-177 (2007).
-
(2007)
Mol. Ther
, vol.16
, pp. 170-177
-
-
Sano, M.1
Li, H.2
Nakanishi, M.3
Rossi, J.J.4
-
41
-
-
33751001588
-
Silencing of HIV-1 with RNA interference: A multiple shRNA approach
-
Ter Brake O, Konstantinova P, Ceylan M, Berkhout B: Silencing of HIV-1 with RNA interference: a multiple shRNA approach. Mol. Ther. 14, 883-892 (2006).
-
(2006)
Mol. Ther
, vol.14
, pp. 883-892
-
-
Ter Brake, O.1
Konstantinova, P.2
Ceylan, M.3
Berkhout, B.4
-
42
-
-
39849108343
-
Lentiviral vector design for multiple shRNA expression and durable HIV-1 inhibition
-
Epub ahead of print
-
Ter Brake O, Hooft KT, Liu YP. Centlivre M, Jasmijn von Eije K, Berkhout B: Lentiviral vector design for multiple shRNA expression and durable HIV-1 inhibition. Mol. Ther. (2008) (Epub ahead of print).
-
(2008)
Mol. Ther
-
-
Ter Brake, O.1
Hooft, K.T.2
Liu, Y.P.3
Centlivre, M.4
Jasmijn von Eije, K.5
Berkhout, B.6
-
43
-
-
27744605569
-
Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy
-
Li MJ, Kim J, Li S et al.: Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy. Mol. Ther. 12, 900-909 (2005).
-
(2005)
Mol. Ther
, vol.12
, pp. 900-909
-
-
Li, M.J.1
Kim, J.2
Li, S.3
-
44
-
-
1642564331
-
Bispecific short hairpin siRNA constructs targeted to CD4, CXCR4, and CCR5 confer HIV-1 resistance
-
Anderson J, Banerjea A, Akkina R: Bispecific short hairpin siRNA constructs targeted to CD4, CXCR4, and CCR5 confer HIV-1 resistance. Oligonucleotides 13, 303-312 (2003).
-
(2003)
Oligonucleotides
, vol.13
, pp. 303-312
-
-
Anderson, J.1
Banerjea, A.2
Akkina, R.3
-
45
-
-
0041322735
-
Potent suppression of HIV type 1 infection by a short hairpin anti-CXCR4 siRNA
-
Anderson J, Banerjea A, Planelles V, Akkina R: Potent suppression of HIV type 1 infection by a short hairpin anti-CXCR4 siRNA. AIDS Res. Hum. Retroviruses 19, 699-706 (2003).
-
(2003)
AIDS Res. Hum. Retroviruses
, vol.19
, pp. 699-706
-
-
Anderson, J.1
Banerjea, A.2
Planelles, V.3
Akkina, R.4
-
46
-
-
0037032933
-
Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication
-
Martinez MA, Gutiérrez A, Armand-Ugón M et al.: Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication. AIDS 16, 2385-2390 (2002):
-
(2002)
AIDS
, vol.16
, pp. 2385-2390
-
-
Martinez, M.A.1
Gutiérrez, A.2
Armand-Ugón, M.3
-
47
-
-
9944222768
-
Inhibition of HIV-1 fusion with small interfering RNAs targeting the chemokine coreceptor CXCR4
-
Zhou N, Fang J, Mukhtar M, Acheampong E, Pomerantz RJ: Inhibition of HIV-1 fusion with small interfering RNAs targeting the chemokine coreceptor CXCR4. Gene Ther. 11, 1703-1712 (2004).
-
(2004)
Gene Ther
, vol.11
, pp. 1703-1712
-
-
Zhou, N.1
Fang, J.2
Mukhtar, M.3
Acheampong, E.4
Pomerantz, R.J.5
-
48
-
-
15844388931
-
Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
-
Liu R, Paxton WA, Choe S et al.: Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 86, 367-377 (1996).
-
(1996)
Cell
, vol.86
, pp. 367-377
-
-
Liu, R.1
Paxton, W.A.2
Choe, S.3
-
49
-
-
34548779028
-
Stable reduction of CCR5 by RNAi through hematopoletic stem cell transplant in non-human primates
-
An DS, Donahue RE, Kamata M et al.: Stable reduction of CCR5 by RNAi through hematopoletic stem cell transplant in non-human primates. Proc. Natl Acad. Sci. USA 104, 13110-13115 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 13110-13115
-
-
An, D.S.1
Donahue, R.E.2
Kamata, M.3
-
50
-
-
0032482926
-
Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice
-
Ma Q, Jones D, Borghesani PR et al.: Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice. Proc. Natl Acad. Sci. USA 95, 9448-9453 (1998).
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 9448-9453
-
-
Ma, Q.1
Jones, D.2
Borghesani, P.R.3
-
51
-
-
0025817991
-
+ cells but markedly decreased helper cell activity in mice lacking CD4
-
+ cells but markedly decreased helper cell activity in mice lacking CD4. Nature 353, 180-184 (1991).
-
(1991)
Nature
, vol.353
, pp. 180-184
-
-
Rahemtulla, A.1
Fung-Leung, W.P.2
Schilham, M.W.3
-
52
-
-
36849042601
-
RNA interference against viruses: Strike and counterstrike
-
Haasnoot J, Westerhout EM, Berkhout B: RNA interference against viruses: strike and counterstrike. Nat. Biotech. 25, 1435-1443 (2007).
-
(2007)
Nat. Biotech
, vol.25
, pp. 1435-1443
-
-
Haasnoot, J.1
Westerhout, E.M.2
Berkhout, B.3
-
53
-
-
1542328263
-
Genetic analysis of RNA-mediated transcriptional gene silencing
-
Matzke M, Aufsatz W, Kanno T et al.: Genetic analysis of RNA-mediated transcriptional gene silencing. Biochim. Biophys. Acta 1677, 129-141 (2004).
-
(2004)
Biochim. Biophys. Acta
, vol.1677
, pp. 129-141
-
-
Matzke, M.1
Aufsatz, W.2
Kanno, T.3
-
54
-
-
0034596989
-
Transcriptional silencing and promoter methylation triggered by double-stranded RNA
-
Mette MF, Aufsatz W, van der Winden J, Matzke MA, Matzke AJ: Transcriptional silencing and promoter methylation triggered by double-stranded RNA. EMBO J. 19, 5194-5201 (2000).
-
(2000)
EMBO J
, vol.19
, pp. 5194-5201
-
-
Mette, M.F.1
Aufsatz, W.2
van der Winden, J.3
Matzke, M.A.4
Matzke, A.J.5
-
55
-
-
0028031830
-
RNA-directed de novo methylation of genomic sequences in plants
-
Wassenegger M, Heimes S, Riedel L, Sanger HL: RNA-directed de novo methylation of genomic sequences in plants. Cell 76, 567-576 (1994).
-
(1994)
Cell
, vol.76
, pp. 567-576
-
-
Wassenegger, M.1
Heimes, S.2
Riedel, L.3
Sanger, H.L.4
-
56
-
-
0036184188
-
RNAi related mechanisms affect both transcriptional and posttranscriptional transgene silencing in Drosophila
-
Pal-Bhadra M, Bhadra U, Birchler JA: RNAi related mechanisms affect both transcriptional and posttranscriptional transgene silencing in Drosophila. Mol. Cell 9, 315-327 (2002).
-
(2002)
Mol. Cell
, vol.9
, pp. 315-327
-
-
Pal-Bhadra, M.1
Bhadra, U.2
Birchler, J.A.3
-
57
-
-
0942279615
-
Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery
-
Pal-Bhadra M, Leibovitch BA, Gandhi SG et al.: Heterochromatic silencing and HP1 localization in Drosophila are dependent on the RNAi machinery. Science 303, 669-672 (2004).
-
(2004)
Science
, vol.303
, pp. 669-672
-
-
Pal-Bhadra, M.1
Leibovitch, B.A.2
Gandhi, S.G.3
-
58
-
-
0037072661
-
Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi
-
Volpe TA, Kidner C, Hall IM, Teng G, Grewal SIS, Martienssen RA: Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science 297, 1833-1837 (2002).
-
(2002)
Science
, vol.297
, pp. 1833-1837
-
-
Volpe, T.A.1
Kidner, C.2
Hall, I.M.3
Teng, G.4
Grewal, S.I.S.5
Martienssen, R.A.6
-
59
-
-
34249304470
-
Transcription and RNA interference in the formation of heterochromatin
-
Grewal SI, Elgin SC: Transcription and RNA interference in the formation of heterochromatin. Nature 447, 399-406 (2007).
-
(2007)
Nature
, vol.447
, pp. 399-406
-
-
Grewal, S.I.1
Elgin, S.C.2
-
60
-
-
10644237968
-
RNAi-mediated pathways in the nucleus
-
Matzke MA, Birchler JA: RNAi-mediated pathways in the nucleus. Nat. Rev. Genet. 6, 24-35 (2005).
-
(2005)
Nat. Rev. Genet
, vol.6
, pp. 24-35
-
-
Matzke, M.A.1
Birchler, J.A.2
-
61
-
-
34250670476
-
Studies on the mechanism of RNAi-dependent heterochromatin assembly
-
Moazed D, Buhler M, Buker SM et al.: Studies on the mechanism of RNAi-dependent heterochromatin assembly. Cold Spring Harb. Symp. Quant. Biol. 71, 461-471 (2006).
-
(2006)
Cold Spring Harb. Symp. Quant. Biol
, vol.71
, pp. 461-471
-
-
Moazed, D.1
Buhler, M.2
Buker, S.M.3
-
63
-
-
4344705410
-
Small interfering RNA-induced transcriptional gene silencing in human cells
-
Morris KV, Chan SWL, Jacobsen SE, Looney DJ: Small interfering RNA-induced transcriptional gene silencing in human cells. Science 305, 1289-1292 (2004).
-
(2004)
Science
, vol.305
, pp. 1289-1292
-
-
Morris, K.V.1
Chan, S.W.L.2
Jacobsen, S.E.3
Looney, D.J.4
-
64
-
-
20844435197
-
Short hairpin RNA-directed cytosine (CpG) methylation of the RASSF1A gene promoter in HeLa cells
-
Castanotto D, Tommasi S, Li MJ et al.: Short hairpin RNA-directed cytosine (CpG) methylation of the RASSF1A gene promoter in HeLa cells. Mol. Ther. 12, 179-183 (2005).
-
(2005)
Mol. Ther
, vol.12
, pp. 179-183
-
-
Castanotto, D.1
Tommasi, S.2
Li, M.J.3
-
65
-
-
34249930701
-
Short hairpin RNA causes the methylation of transforming growth factor-β receptor II promoter and silencing of the target gene in rat hepatic stellate cells
-
Kim J-W, Zhang Y-H, Zero MA, Rossi JJ, Wu J: Short hairpin RNA causes the methylation of transforming growth factor-β receptor II promoter and silencing of the target gene in rat hepatic stellate cells. Biochem. Biophys. Res. Commun. 359, 292-297 (2007).
-
(2007)
Biochem. Biophys. Res. Commun
, vol.359
, pp. 292-297
-
-
Kim, J.-W.1
Zhang, Y.-H.2
Zero, M.A.3
Rossi, J.J.4
Wu, J.5
-
66
-
-
4444314502
-
Double-stranded siRNA targeted to the huntingtin gene does not induce DNA methylation
-
Park CW, Chen Z, Kren BT, Steer CJ: Double-stranded siRNA targeted to the huntingtin gene does not induce DNA methylation. Biochem. Biophys. Res. Commun. 323, 275-280 (2004).
-
(2004)
Biochem. Biophys. Res. Commun
, vol.323
, pp. 275-280
-
-
Park, C.W.1
Chen, Z.2
Kren, B.T.3
Steer, C.J.4
-
67
-
-
23044507007
-
Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation
-
Ting AH, Schuebel KE, Herman JG, Baylin SB: Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation. Nat. Genet. 37, 906-910 (2005).
-
(2005)
Nat. Genet
, vol.37
, pp. 906-910
-
-
Ting, A.H.1
Schuebel, K.E.2
Herman, J.G.3
Baylin, S.B.4
-
68
-
-
34547626629
-
Promoter-associated RNA is required for RNA-directed transriptional gene silencing in human cells
-
Han J, Kim D, Morris KV: Promoter-associated RNA is required for RNA-directed transriptional gene silencing in human cells. Proc. Natl Acad. Sci. USA 104, 12422-12427 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 12422-12427
-
-
Han, J.1
Kim, D.2
Morris, K.V.3
-
69
-
-
33748368912
-
Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells
-
Kim DH, Villeneuve LM, Morris KV, Rossi JJ: Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells. Nat. Struct. Mol. Biol. 13, 793-797 (2006).
-
(2006)
Nat. Struct. Mol. Biol
, vol.13
, pp. 793-797
-
-
Kim, D.H.1
Villeneuve, L.M.2
Morris, K.V.3
Rossi, J.J.4
-
70
-
-
31044433795
-
The antisense strand of small interfering RNAs directs histone methylation and transcriptional gene silencing in human cells
-
Weinberg MS, Villeneuve LM, Ehsani A et al.: The antisense strand of small interfering RNAs directs histone methylation and transcriptional gene silencing in human cells. RNA 12, 256-262 (2006).
-
(2006)
RNA
, vol.12
, pp. 256-262
-
-
Weinberg, M.S.1
Villeneuve, L.M.2
Ehsani, A.3
-
71
-
-
33748339362
-
Involvement of AGO1 and AGO2 in mammalian transcriptional silencing
-
Janowski BA, Huffman KE, Schwartz JC et al.: Involvement of AGO1 and AGO2 in mammalian transcriptional silencing. Nat. Struct. Mol. Biol. 13, 787-792 (2006).
-
(2006)
Nat. Struct. Mol. Biol
, vol.13
, pp. 787-792
-
-
Janowski, B.A.1
Huffman, K.E.2
Schwartz, J.C.3
-
72
-
-
10344250458
-
Components of the DNA methylation system of chromatin control are RNA-binding proteins
-
Jeffery L, Nakielny S: Components of the DNA methylation system of chromatin control are RNA-binding proteins. J. Biol. Chem. 279, 49479-49487 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 49479-49487
-
-
Jeffery, L.1
Nakielny, S.2
-
73
-
-
32844459336
-
The Polycomb group protein EZH2 directly controls DNA methylation
-
Vire E, Brenner C, Deplus R et al.: The Polycomb group protein EZH2 directly controls DNA methylation. Nature 439, 871-874 (2006).
-
(2006)
Nature
, vol.439
, pp. 871-874
-
-
Vire, E.1
Brenner, C.2
Deplus, R.3
-
74
-
-
0035873225
-
Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription
-
Fuks F, Burgers WA, Godin N, Kasai M, Kouzarides T: Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription. EMBO J. 20, 2536-2544 (2001).
-
(2001)
EMBO J
, vol.20
, pp. 2536-2544
-
-
Fuks, F.1
Burgers, W.A.2
Godin, N.3
Kasai, M.4
Kouzarides, T.5
-
75
-
-
31044436469
-
Prolonged transriptional silencing and CpG methylation induced by dsRNAs targeted to the HIV-1 promoter region
-
Suzuki K, Shijuuku T, Fukamachi T et al.: Prolonged transriptional silencing and CpG methylation induced by dsRNAs targeted to the HIV-1 promoter region. J. RNAi Gene Silenc. 1, 66-78 (2005).
-
(2005)
J. RNAi Gene Silenc
, vol.1
, pp. 66-78
-
-
Suzuki, K.1
Shijuuku, T.2
Fukamachi, T.3
-
76
-
-
33646365600
-
Are viral-encoded microRNAs mediating latent HIV-1 infection?
-
Weinberg MS, Morris KV: Are viral-encoded microRNAs mediating latent HIV-1 infection? DNA Cell Biol. 25, 223-231 (2006).
-
(2006)
DNA Cell Biol
, vol.25
, pp. 223-231
-
-
Weinberg, M.S.1
Morris, K.V.2
-
77
-
-
0025876881
-
Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR
-
Gatignol A, Buckler-White A, Berkhout B, Jeang K-T: Characterization of a human TAR RNA-binding protein that activates the HIV-1 LTR. Science 251, 1597-1600 (1991).
-
(1991)
Science
, vol.251
, pp. 1597-1600
-
-
Gatignol, A.1
Buckler-White, A.2
Berkhout, B.3
Jeang, K.-T.4
-
78
-
-
34548304523
-
HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR
-
Klase Z, Kale P, Winograd R et al.: HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR. BMC Mol. Biol. 8, 63 (2007).
-
(2007)
BMC Mol. Biol
, vol.8
, pp. 63
-
-
Klase, Z.1
Kale, P.2
Winograd, R.3
-
79
-
-
42449121863
-
Identification of functional microRNAs released through asymmetrical processing of HIV-1 TAR element
-
Ouellet DL, Plante I, Landry P et al.: Identification of functional microRNAs released through asymmetrical processing of HIV-1 TAR element. Nucleic Acids Res. 36, 2353-2365 (2008).
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 2353-2365
-
-
Ouellet, D.L.1
Plante, I.2
Landry, P.3
-
80
-
-
0031455415
-
Histone acetyltransferases regulate HIV-1 enhancer activity in vitro
-
Sheridan PL, Mayall TP, Verdin E, Jones KA: Histone acetyltransferases regulate HIV-1 enhancer activity in vitro. Genes Dev. 11, 3327-3340 (1997).
-
(1997)
Genes Dev
, vol.11
, pp. 3327-3340
-
-
Sheridan, P.L.1
Mayall, T.P.2
Verdin, E.3
Jones, K.A.4
-
81
-
-
0029919356
-
Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation
-
Van Lint C, Emiliani S, Ott M, Verdin E: Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation. EMBO J. 15, 1112-1120 (1996).
-
(1996)
EMBO J
, vol.15
, pp. 1112-1120
-
-
Van Lint, C.1
Emiliani, S.2
Ott, M.3
Verdin, E.4
-
82
-
-
2942586974
-
Coaxing HIV-1 from resting CD4 T cells: Histone deacetylase inhibition allows latent vital expression
-
Ylisastigui LA, Archin NMA, Lehrman GA, Bosch RJC, Margolis DMAB: Coaxing HIV-1 from resting CD4 T cells: histone deacetylase inhibition allows latent vital expression. AIDS 18, 1101-1108 (2004).
-
(2004)
AIDS
, vol.18
, pp. 1101-1108
-
-
Ylisastigui, L.A.1
Archin, N.M.A.2
Lehrman, G.A.3
Bosch, R.J.C.4
Margolis, D.M.A.B.5
-
83
-
-
0036232430
-
Counterregulation of chromatin deacetylation and histone deacetylase occupancy at the integrated promoter of human immunodeficiency virus type 1 (HIV-1) by the HIV-1 repressor YY1 and HIV-1 activator Tat
-
He G, Margolis DM: Counterregulation of chromatin deacetylation and histone deacetylase occupancy at the integrated promoter of human immunodeficiency virus type 1 (HIV-1) by the HIV-1 repressor YY1 and HIV-1 activator Tat. Mol. Cell. Biol. 22, 2965-2973 (2002).
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 2965-2973
-
-
He, G.1
Margolis, D.M.2
-
84
-
-
30444431914
-
NF-κB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation
-
Williams S, Chen L-F, Kwon H, Ruiz-Jarabo C, Verdin E, Greene W: NF-κB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. EMBO J. 25, 139-149 (2006).
-
(2006)
EMBO J
, vol.25
, pp. 139-149
-
-
Williams, S.1
Chen, L.-F.2
Kwon, H.3
Ruiz-Jarabo, C.4
Verdin, E.5
Greene, W.6
-
85
-
-
35148858784
-
c-Myc and Sp1 contribute to proviral latency by recruiting histone deacetylase 1 to the human immunodeficiency virus type 1 promoter
-
Jiang G, Espeseth A, Hazuda DJ, Margolis DM: c-Myc and Sp1 contribute to proviral latency by recruiting histone deacetylase 1 to the human immunodeficiency virus type 1 promoter. J. Virol. 81, 10914-10923 (2007).
-
(2007)
J. Virol
, vol.81
, pp. 10914-10923
-
-
Jiang, G.1
Espeseth, A.2
Hazuda, D.J.3
Margolis, D.M.4
-
86
-
-
33846506800
-
Suv39H1 and HP1γ are responsible for chromatin-mediated HIV-1 transcriptional silencing and post-integration latency
-
du Chene I, Basyuk E, Lin YL et al.: Suv39H1 and HP1γ are responsible for chromatin-mediated HIV-1 transcriptional silencing and post-integration latency. EMBO J. 26, 424-435 (2007).
-
(2007)
EMBO J
, vol.26
, pp. 424-435
-
-
du Chene, I.1
Basyuk, E.2
Lin, Y.L.3
-
88
-
-
34447535345
-
Engineering targeted viral vectors for gene therapy
-
Waehler R, Russell SJ, Curtel DT: Engineering targeted viral vectors for gene therapy. Nat. Rev. Genet. 8, 573-587 (2007).
-
(2007)
Nat. Rev. Genet
, vol.8
, pp. 573-587
-
-
Waehler, R.1
Russell, S.J.2
Curtel, D.T.3
-
89
-
-
4644258829
-
Adenoviral vectors for gene transfer and therapy
-
Volpers C, Kochanek S: Adenoviral vectors for gene transfer and therapy. J. Gene Med. 6, S164-S171 (2004).
-
(2004)
J. Gene Med
, vol.6
-
-
Volpers, C.1
Kochanek, S.2
-
90
-
-
34548034889
-
Building an HIV-proof immune system
-
Cohen J: Building an HIV-proof immune system. Science 317, 612-614 (2007).
-
(2007)
Science
, vol.317
, pp. 612-614
-
-
Cohen, J.1
-
92
-
-
0037448352
-
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
-
Hacein-Bey-Abina S, von Kalle C, Schmidt M et al.: A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. N. Engl. J. Med. 348, 255-256 (2003).
-
(2003)
N. Engl. J. Med
, vol.348
, pp. 255-256
-
-
Hacein-Bey-Abina, S.1
von Kalle, C.2
Schmidt, M.3
-
93
-
-
0142084745
-
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
-
Hacein-Bey-Abina S, Von Kalle C, Schmidt M et al.: LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 302, 415-419 (2003).
-
(2003)
Science
, vol.302
, pp. 415-419
-
-
Hacein-Bey-Abina, S.1
Von Kalle, C.2
Schmidt, M.3
-
94
-
-
14844339323
-
Gene therapy: Panel urges limits on X-SCID trials
-
Kaiser J: Gene therapy: panel urges limits on X-SCID trials. Science 307, 1544a-1545a (2005).
-
(2005)
Science
, vol.307
-
-
Kaiser, J.1
-
95
-
-
19344375031
-
Retroviral DNA integration: ASLV, HIV and MLV show distinct target site preferences
-
Mitchell RS, Beitzel BF, Schroder ARW et al.: Retroviral DNA integration: ASLV, HIV and MLV show distinct target site preferences. PLoS Biol. 2, e234 (2004).
-
(2004)
PLoS Biol
, vol.2
-
-
Mitchell, R.S.1
Beitzel, B.F.2
Schroder, A.R.W.3
-
96
-
-
0037841763
-
Transcription start regions in the human genome are favored targets for MLV integration
-
Wu X, Li Y, Crise B, Burgess SM: Transcription start regions in the human genome are favored targets for MLV integration. Science 300, 1749-1751 (2003).
-
(2003)
Science
, vol.300
, pp. 1749-1751
-
-
Wu, X.1
Li, Y.2
Crise, B.3
Burgess, S.M.4
-
97
-
-
34249906359
-
Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy
-
Deichmann A, Hacein-Bey-Abina S, Schmidt M et al.: Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy. J. Clin. Invest. 117, 2225-2232 (2007).
-
(2007)
J. Clin. Invest
, vol.117
, pp. 2225-2232
-
-
Deichmann, A.1
Hacein-Bey-Abina, S.2
Schmidt, M.3
-
98
-
-
33745225238
-
Fragile sites are preferential targets for integrations of MLV vectors in gene therapy
-
Bester AC, Schwartz M, Schmidt M et al.: Fragile sites are preferential targets for integrations of MLV vectors in gene therapy. Gene Ther. 13, 1057-1059 (2006).
-
(2006)
Gene Ther
, vol.13
, pp. 1057-1059
-
-
Bester, A.C.1
Schwartz, M.2
Schmidt, M.3
-
99
-
-
0037162715
-
HIV-1 integration in the human genome favors active genes and local hotspots
-
Schröder AR, Shinn P, Chen H, Berry C, Ecker JR, Bushman F: HIV-1 integration in the human genome favors active genes and local hotspots. Cell 110, 521-529 (2002).
-
(2002)
Cell
, vol.110
, pp. 521-529
-
-
Schröder, A.R.1
Shinn, P.2
Chen, H.3
Berry, C.4
Ecker, J.R.5
Bushman, F.6
-
101
-
-
0026623010
-
Packaging system for rapid production of murine leukemia virus vectors with variable tropism
-
Landau NR, Littman DR: Packaging system for rapid production of murine leukemia virus vectors with variable tropism. J. Virol. 66, 5110-5113 (1992).
-
(1992)
J. Virol
, vol.66
, pp. 5110-5113
-
-
Landau, N.R.1
Littman, D.R.2
-
102
-
-
0346132122
-
Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells
-
Yu S-F, Ruden TV, Kantoff PW et al.: Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells. Proc. Natl Acad Sci. USA 83, 3194-3198 (1986).
-
(1986)
Proc. Natl Acad Sci. USA
, vol.83
, pp. 3194-3198
-
-
Yu, S.-F.1
Ruden, T.V.2
Kantoff, P.W.3
-
103
-
-
0023218033
-
Handicapped retroviral vectors efficiently transduce foreign genes into hematopoietic stem cells
-
Hawley RG, Covarrubias L, Hawley T, Mintz B: Handicapped retroviral vectors efficiently transduce foreign genes into hematopoietic stem cells. Proc. Natl Acad. Sci. USA 84, 2406-2410 (1987).
-
(1987)
Proc. Natl Acad. Sci. USA
, vol.84
, pp. 2406-2410
-
-
Hawley, R.G.1
Covarrubias, L.2
Hawley, T.3
Mintz, B.4
-
104
-
-
0023390429
-
Gene expression from transcriptionally disabled retroviral vectors
-
Yee J-K, Moores JC, Jony DJ, Wolff JA, Respess JG, Friedmann T: Gene expression from transcriptionally disabled retroviral vectors. Proc. Natl Acad. Sci. USA 84, 5197-5201 (1987).
-
(1987)
Proc. Natl Acad. Sci. USA
, vol.84
, pp. 5197-5201
-
-
Yee, J.-K.1
Moores, J.C.2
Jony, D.J.3
Wolff, J.A.4
Respess, J.G.5
Friedmann, T.6
-
105
-
-
33845994066
-
+ hematopoietic progenitor cells potently inhibits human immunodeficiency virus-1 replication
-
+ hematopoietic progenitor cells potently inhibits human immunodeficiency virus-1 replication. Mol. Ther. 15, 76-85 (2007).
-
(2007)
Mol. Ther
, vol.15
, pp. 76-85
-
-
Bahner, I.1
Sumiyoshi, T.2
Kagoda, M.3
-
106
-
-
33845668311
-
RNAi in combination with a ribozyme and TAR decoy for treatment of HIV infection in hematopoietic cell gene therapy
-
Li M, Li H, Rossi JJ: RNAi in combination with a ribozyme and TAR decoy for treatment of HIV infection in hematopoietic cell gene therapy. Ann. NY Acad Sci. 1082, 172-179 (2006).
-
(2006)
Ann. NY Acad Sci
, vol.1082
, pp. 172-179
-
-
Li, M.1
Li, H.2
Rossi, J.J.3
-
107
-
-
0037422583
-
Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5
-
Qin X-E An DS, Chen ISY, Baltimore D: Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc. Natl Acad. Sci. USA 100, 183-188 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 183-188
-
-
Qin, X.-E.1
An, D.S.2
Chen, I.S.Y.3
Baltimore, D.4
-
108
-
-
0036229427
-
Design of HIV vectors for efficient gene delivery into human hematopoietic cells
-
Yam PY, Li S, Wu J, Hu J, Zaia JA, Yee J-K: Design of HIV vectors for efficient gene delivery into human hematopoietic cells. Mol. Ther. 5, 479-484 (2002).
-
(2002)
Mol. Ther
, vol.5
, pp. 479-484
-
-
Yam, P.Y.1
Li, S.2
Wu, J.3
Hu, J.4
Zaia, J.A.5
Yee, J.-K.6
-
109
-
-
0029764099
-
A conditionally replicating HIV-1 vector interferes with wild-type HIV-1 replication and spread
-
Dropulic B, Hermankova M, Pitha PM: A conditionally replicating HIV-1 vector interferes with wild-type HIV-1 replication and spread. Proc. Natl Acad. Sci. USA 93, 11103-11108 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 11103-11108
-
-
Dropulic, B.1
Hermankova, M.2
Pitha, P.M.3
-
110
-
-
0034694022
-
Lentivirus vector mobilization and spread by human immunodeficiency virus
-
Evans JT, Garcia JV: Lentivirus vector mobilization and spread by human immunodeficiency virus. Hum. Gene Ther. 11, 2331-2339 (2000).
-
(2000)
Hum. Gene Ther
, vol.11
, pp. 2331-2339
-
-
Evans, J.T.1
Garcia, J.V.2
-
111
-
-
0141570489
-
Theoretical design of a gene therapy to prevent AIDS but not human immunodeficiency virus type 1 infection
-
Weinberger LS, Schaffer DV, Arkin AP: Theoretical design of a gene therapy to prevent AIDS but not human immunodeficiency virus type 1 infection. J. Virol. 77, 10028-10036 (2003).
-
(2003)
J. Virol
, vol.77
, pp. 10028-10036
-
-
Weinberger, L.S.1
Schaffer, D.V.2
Arkin, A.P.3
-
112
-
-
29244455328
-
Characterization of human immunodeficiency virus (HIV)-2 vector mobilization by HIV-1
-
Morris KV, Looney DJ: Characterization of human immunodeficiency virus (HIV)-2 vector mobilization by HIV-1. Hum. Gene Ther. 16, 1463-1472 (2005).
-
(2005)
Hum. Gene Ther
, vol.16
, pp. 1463-1472
-
-
Morris, K.V.1
Looney, D.J.2
-
113
-
-
0038801439
-
An inducible human immunodeficiency virus type 1 (HIV-1) vector which effectively suppresses HIV-1 replication
-
An DS, Morizono K, Li Q-X, Mao SH, Lu S, Chen ISY: An inducible human immunodeficiency virus type 1 (HIV-1) vector which effectively suppresses HIV-1 replication. J. Virol. 73, 7671-7677 (1999).
-
(1999)
J. Virol
, vol.73
, pp. 7671-7677
-
-
An, D.S.1
Morizono, K.2
Li, Q.-X.3
Mao, S.H.4
Lu, S.5
Chen, I.S.Y.6
-
114
-
-
0032796643
-
Interaction of human immunodeficiency virus-derived vectors with wild-type virus in transduced cells
-
Bukovsky AA, Song JP, Naldini LL: Interaction of human immunodeficiency virus-derived vectors with wild-type virus in transduced cells. J. Virol. 73, 7087-7092 (1999).
-
(1999)
J. Virol
, vol.73
, pp. 7087-7092
-
-
Bukovsky, A.A.1
Song, J.P.2
Naldini, L.L.3
-
115
-
-
0032502646
-
Anti-HIV effects of HIV vectors
-
Corbeau P, Wong-Staal F: Anti-HIV effects of HIV vectors. Virology 243, 268-274 (1998).
-
(1998)
Virology
, vol.243
, pp. 268-274
-
-
Corbeau, P.1
Wong-Staal, F.2
-
116
-
-
33751251058
-
Gene transfer in humans using a conditionally replicating lentiviral vector
-
Levine BL, Humeau LM, Boyer J et al.: Gene transfer in humans using a conditionally replicating lentiviral vector. Proc. Natl Acad. Sci. USA 103, 17372-17377 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 17372-17377
-
-
Levine, B.L.1
Humeau, L.M.2
Boyer, J.3
-
117
-
-
33745299723
-
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
-
Grimm D, Streetz KL, Jopling CL et al.: Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature 441, 537-541 (2006).
-
(2006)
Nature
, vol.441
, pp. 537-541
-
-
Grimm, D.1
Streetz, K.L.2
Jopling, C.L.3
-
118
-
-
33745608078
-
Off-target effects by siRNA can induce toxic phenotype
-
Fedorov Y, Anderson EM, Birmingham A et al.: Off-target effects by siRNA can induce toxic phenotype. RNA 12, 1188-1196 (2006).
-
(2006)
RNA
, vol.12
, pp. 1188-1196
-
-
Fedorov, Y.1
Anderson, E.M.2
Birmingham, A.3
-
119
-
-
0034958582
-
Defective lentiviral vectors are efficiently trafficked by HIV-1 and inhibit its replication
-
Klimatcheva E, Planelles V, Day SL, Fulreader F, Renda MJ, Rosenblatt J: Defective lentiviral vectors are efficiently trafficked by HIV-1 and inhibit its replication. Mol. Ther. 3, 928-939 (2001).
-
(2001)
Mol. Ther
, vol.3
, pp. 928-939
-
-
Klimatcheva, E.1
Planelles, V.2
Day, S.L.3
Fulreader, F.4
Renda, M.J.5
Rosenblatt, J.6
-
120
-
-
37549039802
-
An RNA targeted to the HIV-1 LTR promoter modulates indiscriminate off-target gene activation
-
Weinberg MS, Barichievy S, Schaffer L, Han J, Morris KV: An RNA targeted to the HIV-1 LTR promoter modulates indiscriminate off-target gene activation. Nucleic Acids Res. 35(21), 7303-7312 (2007).
-
(2007)
Nucleic Acids Res
, vol.35
, Issue.21
, pp. 7303-7312
-
-
Weinberg, M.S.1
Barichievy, S.2
Schaffer, L.3
Han, J.4
Morris, K.V.5
-
121
-
-
33847081733
-
Activating gene expression in mammalian cells with promoter-targeted duplex RNAs
-
Janowski BA, Younger ST, Hardy DB, Ram R, Huffman KE, Corey DR: Activating gene expression in mammalian cells with promoter-targeted duplex RNAs. Nat. Chem. Biol. 3, 166-173 (2007).
-
(2007)
Nat. Chem. Biol
, vol.3
, pp. 166-173
-
-
Janowski, B.A.1
Younger, S.T.2
Hardy, D.B.3
Ram, R.4
Huffman, K.E.5
Corey, D.R.6
-
122
-
-
33751251990
-
Small dsRNAs induce transcriptional activation in human cells
-
Li L-C, Okino ST, Zhao H et al.: Small dsRNAs induce transcriptional activation in human cells. Proc. Natl Acad. Sci. USA 103, 17337-17342 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 17337-17342
-
-
Li, L.-C.1
Okino, S.T.2
Zhao, H.3
-
123
-
-
36749026906
-
Switching from repression to activation: MicroRNAs can up-regulate translation
-
Vasudevan S, Tong Y, Steitz JA: Switching from repression to activation: microRNAs can up-regulate translation. Science 318(5858), 1931-1934 (2007).
-
(2007)
Science
, vol.318
, Issue.5858
, pp. 1931-1934
-
-
Vasudevan, S.1
Tong, Y.2
Steitz, J.A.3
|