A novel insulin-sodium oleate complex for oral administration: Preparation, characterization and in vivo evaluation

Journal of Drug Delivery Science and Technology

Volumn 18, Issue 4, 2008, Pages 239-243

  Sun, S ^a,b   Cui, Fude ^a   Kawashima, Y ^c   Liang, N ^d   Zhang, L ^a   Shi, K ^a   Yu, Y ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b HEILONGJIANG UNIVERSITY   (China)

^c AICHI GAKUIN UNIVERSITY   (Japan)

^d Tianjin Medical College   (China)

Author keywords

DSC; FTIR; Hydrophobic ion pairing (HIP); Insulin complex; Pharmacological activity

Indexed keywords

ANTIDIABETIC AGENT; INSULIN SODIUM OLEATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG ABSORPTION; DRUG ADMINISTRATION ROUTE; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG SYNTHESIS; GLUCOSE BLOOD LEVEL; IN VIVO STUDY; INFRARED SPECTROSCOPY; MALE; NONHUMAN; PARTICLE SIZE; PARTITION COEFFICIENT; WISTAR RAT;

EID: 52649159264     PISSN: 17732247     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1773-2247(08)50047-5     Document Type: Article

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