Extended-spectrum β-lactamase-producing Klebsiella pneumoniae in paediatric wards: A nested case-control study

Journal of Paediatrics and Child Health

Volumn 44, Issue 10, 2008, Pages 548-553

  Demir, Serap ^a   Soysal, Ahmet ^a   Bakir, Mustafa ^a   Kaufmann, Mary E ^b   Yagci, Aysegul ^a,c  

^a MARMARA UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

^b PUBLIC HEALTH ENGLAND   (United Kingdom)

^c Department of Clinical Microbiology ^*  (Turkey)

Author keywords

Beta lactamase; Infection control; Klebsiella pneumoniae

Indexed keywords

EXTENDED SPECTRUM BETA LACTAMASE;

ARTICLE; ARTIFICIAL VENTILATION; BACTERIAL COLONIZATION; BACTERIAL STRAIN; BACTERIAL TRANSMISSION; BACTERIUM ISOLATE; FEMALE; GENOTYPE; HEALTH CARE PERSONNEL; HOSPITAL ADMISSION; HOSPITAL PERSONNEL; HOSPITALIZATION; HUMAN; KLEBSIELLA PNEUMONIAE; MAJOR CLINICAL STUDY; MALE; PEDIATRIC WARD; PRESCHOOL CHILD; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; RISK FACTOR;

BETA-LACTAMASES; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CROSS INFECTION; ELECTROPHORESIS, GEL, PULSED-FIELD; EQUIPMENT CONTAMINATION; FEMALE; HOSPITAL BED CAPACITY, 300 TO 499; HOSPITALS, TEACHING; HUMANS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; LENGTH OF STAY; MALE; MICROBIAL SENSITIVITY TESTS; PHENOTYPE; PROSPECTIVE STUDIES; RESPIRATION, ARTIFICIAL; RISK FACTORS; TURKEY;

EID: 52649155888     PISSN: 10344810     EISSN: 14401754     Source Type: Journal    
DOI: 10.1111/j.1440-1754.2008.01326.x     Document Type: Article

References (20)

1. Bradford PA. Extended spectrum beta lactamases in the 21st century: characterization, epidemiology, and detection of this important resistance threat. Clin. Microbiol. Rev. 2001 14 : 933 51.
2. Knothe H, Shash P, Kremery V, Antal M, Mitsuhashi S. Transferable resistance to cefotaxime, cefoxitin, cefamandole and cefuroxime in clinical isolates of Klebsiella pneumoniae and Serratia marcescens. Infection 1983 11 : 315 7.
3. Bisson G, Fishman NO, Patel JB et al. Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species: risk factors for colonization and impact of antimicrobial formulary interventions on colonization prevalence. Infect. Control. Hosp. Epidemiol. 2002 23 : 254 60.
4. Meyer KS, Urban C, Eagan JA, Berger BJ, Rahall JJ. Nosocomial outbreak of Klebsiella infection resistant to late-generation cephalosporins. Ann. Intern. Med. 1993 119 : 353 8.
5. Pena C, Pujol M, Ardanuy C et al. Epidemiology and successful control of a large outbreak due to Klebsiella pneumoniae producing extended-spectrum beta-lactamases. Antimicrob. Agents Chemother. 1998 42 : 53 8.
6. Garcia-Rodriguez JA, Jones RN, MYSTIC Programme Study Group. Antimicrobial resistance in gram-negative isolates from European intensive care units: data from the Meropenem Yearly Susceptibility Test Information Collection (MYSTIC) programme. J. Chemother. 2002 14 : 25 32.
7. Boo NY, Ng SF, Lim VKE. A case control study of risk factors associated with rectal colonization of extended-spectrum beta-lactamase producing Klebsiella sp in newborn infants. J. Hosp. Infect. 2005 61 : 68 74.
8. Hart CA. Klebsiella and the neonate. J. Hosp. Infect. 1993 23 : 83 6.
9. Hudome SM, Fisher MC. Nosocomial infections in the neonatal intensive care unit. Curr. Opin. Infect. Dis. 2001 14 : 303 7.
10. Hollander R, Ebke M, Barck H, von Pritzbuer E. Asymptomatic carriage of Klebsiella pneumoniae producing extended-spectrum beta-lactamase by patients in a neurological early rehabilitation unit: management of an outbreak. J. Hosp. Infect. 2001 48 : 207 13.
11. Hebert PC, Drummond AJ, Singer J et al. A simple multiple system organ failure scoring system predicts mortality of patients who have sepsis syndrome. Chest 1993 104 : 230 8.
12. Pessoa-Silva CL, Meurer MB, Camara AV et al. Extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in a neonatal intensive care unit: risk factors for infection and colonization. J. Hosp. Infect. 2003 53 : 198 206.
13. Pena C, Pujol M, Ricart A et al. Risk factors for faecal carriage of Klebsiella pneumoniae producing extended spectrum beta-lactamase (ESBL-KP) in the intensive care unit. J. Hosp. Infect. 1997 35 : 9 16.
14. Centers for Disease Control. Guideline for Hand Hygiene in Health-Care Settings. MMWR. Morb. Mortal. Wkly. Rep. 2002 51 : RR 16.
15. Jarlier V, Nicolas MH, Fournier G, Philippon A. Extended broad spectrum beta-lactamases conferring transferable resistance to newer β-lactam agents in Enterobacteriacea: hospital prevalence and susceptibility patterns. Rev. Infect. Dis. 1988 10 : 867 78.
16. Cormican MG, Marshall SA, Jones RN. Detection of extended spectrum beta-lactamase (ESBL)-producing strains in the E-test ESBL screen. J. Clin. Microbiol. 1996 34 : 1880 4.
17. Kaufmann ME. Pulse field gel electrophoresis. In : Woodford N, Johnson AP, eds. Methods in Molecular Medicine, Molecular Bacteriology: Protocols and Clinical Applications. Totowa, NJ : Humana Press, Inc, 1998 33 58.
18. Decre D, Gachot B, Lucet JC et al. Clinical and bacteriologic epidemiology of extended-spectrum beta-lactamase-producing strains of Klebsiella pneumoniae in a medical intensive care unit. Clin. Infect. Dis. 1998 27 : 834 44.
19. Asensio A, Oliver A, Gonzalez-Diego P et al. Outbreak of a multiresistant Klebsiella pneumoniae strain in an intensive care unit: antibiotic use as risk factor for colonization and infection. Clin. Infect. Dis. 2000 30 : 55 60.
20. Lebessi E, Dellagrammaticas H, Tassios PT et al. Extended-spectrum beta-lactamase-producing Klebsiella pneumoniae in a neonatal intensive care unit in the high-prevalence area of Athens, Greece. J. Clin. Microbiol. 2002 40 : 799 804.