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Volumn 5, Issue 3, 2008, Pages 135-140

Combination therapy with phosphodiesterase type V inhibitors and testosterone

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC GMP; NITRIC OXIDE SYNTHASE; PHOSPHODIESTERASE V INHIBITOR; PLACEBO; PROSTAGLANDIN E1; SILDENAFIL; TESTOSTERONE; TESTOSTERONE UNDECANOATE;

EID: 52649140109     PISSN: 15483584     EISSN: 15483592     Source Type: Journal    
DOI: 10.1007/s11930-008-0024-7     Document Type: Review
Times cited : (13)

References (29)
  • 1
    • 33845387023 scopus 로고    scopus 로고
    • Significance of hypogonadism in erectile dysfunction
    • Buvat J, Bou Jaoudé G: Significance of hypogonadism in erectile dysfunction: World J Urol 2006, 24:657-667.
    • (2006) World J Urol , vol.24 , pp. 657-667
    • Buvat, J.1    Bou Jaoudé, G.2
  • 2
    • 33845917336 scopus 로고    scopus 로고
    • Testosterone use in men with sexual dysfunction: A systematic review and meta-analysis of randomized placebo-controlled trials
    • Bolona ER, Uraga MV, Haddad RM, et al.: Testosterone use in men with sexual dysfunction: a systematic review and meta-analysis of randomized placebo-controlled trials. Mayo Clin Proc 2007, 82:20-28.
    • (2007) Mayo Clin Proc , vol.82 , pp. 20-28
    • Bolona, E.R.1    Uraga, M.V.2    Haddad, R.M.3
  • 3
    • 26644446120 scopus 로고    scopus 로고
    • Effects of testosterone on sexual function in men: Results of a meta-analysis
    • Isidori AM, Gianetta E, Gianfrilli D, et al.: Effects of testosterone on sexual function in men: results of a meta-analysis. Clin Endocrinol (Oxf) 2005, 63:381-394.
    • (2005) Clin Endocrinol (Oxf) , vol.63 , pp. 381-394
    • Isidori, A.M.1    Gianetta, E.2    Gianfrilli, D.3
  • 4
    • 12544257318 scopus 로고    scopus 로고
    • Does sildenafil combined with testosterone gel improve erectile dysfunction in hypogonadal men in whom testosterone supplement therapy alone failed?
    • Greenstein A, Mabjeesh NJ, Sofer M, et al.: Does sildenafil combined with testosterone gel improve erectile dysfunction in hypogonadal men in whom testosterone supplement therapy alone failed? J Urol 2005, 173:530-532.
    • (2005) J Urol , vol.173 , pp. 530-532
    • Greenstein, A.1    Mabjeesh, N.J.2    Sofer, M.3
  • 5
    • 33947231295 scopus 로고    scopus 로고
    • Effect of testosterone on intracavernous pressure elicited with electrical stimulation of the medial preoptic area and cavernous nerve in male rats
    • Suzuki N, Sato Y, Hisasue SI, et al.: Effect of testosterone on intracavernous pressure elicited with electrical stimulation of the medial preoptic area and cavernous nerve in male rats. J Androl 2007, 28:218-222.
    • (2007) J Androl , vol.28 , pp. 218-222
    • Suzuki, N.1    Sato, Y.2    Hisasue, S.I.3
  • 6
    • 34249000708 scopus 로고    scopus 로고
    • Testosterone and erectile function: From basic research to new clinical paradigm for managing men with androgen insufficiency and erectile dysfunction
    • Traish A, Goldstein I, Kim NN: Testosterone and erectile function: from basic research to new clinical paradigm for managing men with androgen insufficiency and erectile dysfunction. Eur Urol 2007, 52:54-70.
    • (2007) Eur Urol , vol.52 , pp. 54-70
    • Traish, A.1    Goldstein, I.2    Kim, N.N.3
  • 7
    • 11144355591 scopus 로고    scopus 로고
    • Androgens regulate phosphodiesterase type 5 expression and functional activity in corpora cavernosa
    • Morelli A, Filippi S, Mancina R, et al.: Androgens regulate phosphodiesterase type 5 expression and functional activity in corpora cavernosa. Endocrinology 2004, 145:2253-2263.
    • (2004) Endocrinology , vol.145 , pp. 2253-2263
    • Morelli, A.1    Filippi, S.2    Mancina, R.3
  • 8
    • 13844271285 scopus 로고    scopus 로고
    • Testosterone regulates PDE5 expression and in vivo responsiveness to tadalafil in rat corpus cavernosum
    • Zhang XH, Morelli A, Luconi M, et al.: Testosterone regulates PDE5 expression and in vivo responsiveness to tadalafil in rat corpus cavernosum. Eur Urol 2005, 47:409-416.
    • (2005) Eur Urol , vol.47 , pp. 409-416
    • Zhang, X.H.1    Morelli, A.2    Luconi, M.3
  • 9
    • 33645996073 scopus 로고    scopus 로고
    • Testosterone restores diabetes-induced erectile dysfunction and sildenafil responsiveness in two distinct animal models of chemical diabetes
    • Zhang XH, Filippi S, Morelli A, et al.: Testosterone restores diabetes-induced erectile dysfunction and sildenafil responsiveness in two distinct animal models of chemical diabetes. J Sex Med 2006, 3:253-264.
    • (2006) J Sex Med , vol.3 , pp. 253-264
    • Zhang, X.H.1    Filippi, S.2    Morelli, A.3
  • 10
    • 34249065859 scopus 로고    scopus 로고
    • Testosterone regulates RhoA/ Rho-kinase signaling in two distinct animal models of chemical diabetes
    • Vignozzi L, Morelli A, Filippi S, et al.: Testosterone regulates RhoA/ Rho-kinase signaling in two distinct animal models of chemical diabetes. J Sex Med 2007, 4:620-630.
    • (2007) J Sex Med , vol.4 , pp. 620-630
    • Vignozzi, L.1    Morelli, A.2    Filippi, S.3
  • 11
    • 33646007551 scopus 로고    scopus 로고
    • Dose-response relationship between testosterone an erectile function: Evidence for the existence of a critical threshold
    • Armagan A, Kim NN, Goldstein I, et al.: Dose-response relationship between testosterone an erectile function: evidence for the existence of a critical threshold. J Androl 2006, 27:517-526.
    • (2006) J Androl , vol.27 , pp. 517-526
    • Armagan, A.1    Kim, N.N.2    Goldstein, I.3
  • 12
    • 2442655401 scopus 로고    scopus 로고
    • Androgen and estrogen receptors in the human corpus cavernosum penis: Immunohistochemical and cell culture results
    • Schultheiss D, Badalyan R, Pilatz A, et al.: Androgen and estrogen receptors in the human corpus cavernosum penis: immunohistochemical and cell culture results. World J Urol 2003, 21:320-324.
    • (2003) World J Urol , vol.21 , pp. 320-324
    • Schultheiss, D.1    Badalyan, R.2    Pilatz, A.3
  • 13
    • 2442621211 scopus 로고    scopus 로고
    • Role of androgens in erectile function
    • Foresta C, Caretta N, Rossato M, et al.: Role of androgens in erectile function. J Urol 2004, 171:2358-2362.
    • (2004) J Urol , vol.171 , pp. 2358-2362
    • Foresta, C.1    Caretta, N.2    Rossato, M.3
  • 14
    • 0033792530 scopus 로고    scopus 로고
    • Androgens and penile erection: Evidence for a direct relationship between free testosterone and cavernous vasodilation in men with erectile dysfunction
    • Aversa A, Isidori AM, De Martino MU, et al.: Androgens and penile erection: evidence for a direct relationship between free testosterone and cavernous vasodilation in men with erectile dysfunction. Clin Endocrinol (Oxf) 2000, 53:517-522.
    • (2000) Clin Endocrinol (Oxf) , vol.53 , pp. 517-522
    • Aversa, A.1    Isidori, A.M.2    De Martino, M.U.3
  • 15
    • 0038670738 scopus 로고    scopus 로고
    • Androgens improve cavernous vasodilation and response to sildenafil in patients with erectile dysfunction
    • Aversa A, Isidori AM, Spera G, et al.: Androgens improve cavernous vasodilation and response to sildenafil in patients with erectile dysfunction. Clin Endocrinol (Oxf) 2003, 58:632-638.
    • (2003) Clin Endocrinol (Oxf) , vol.58 , pp. 632-638
    • Aversa, A.1    Isidori, A.M.2    Spera, G.3
  • 16
    • 33644504534 scopus 로고    scopus 로고
    • Sildenafil improves sleep-related erections in hypogonadal men: Evidence from a randomized, placebo-controlled, cross-over study of a synergistic role of both testosterone and sildenafil on penile erections
    • Rochira V, Balestrieri A, Madeo B, et al.: Sildenafil improves sleep-related erections in hypogonadal men: evidence from a randomized, placebo-controlled, cross-over study of a synergistic role of both testosterone and sildenafil on penile erections. J Androl 2006, 27:165-175.
    • (2006) J Androl , vol.27 , pp. 165-175
    • Rochira, V.1    Balestrieri, A.2    Madeo, B.3
  • 17
    • 33644784749 scopus 로고    scopus 로고
    • Adjunctive use of AndroGel (testosterone gel) with sildenafil to treat erectile dysfunction in men with acquired androgen deficiency syndrome after failure using sildenafil alone
    • Rosenthal BD, May NR, Metro MJ, et al.: Adjunctive use of AndroGel (testosterone gel) with sildenafil to treat erectile dysfunction in men with acquired androgen deficiency syndrome after failure using sildenafil alone. Urology 2006, 67:571-574.
    • (2006) Urology , vol.67 , pp. 571-574
    • Rosenthal, B.D.1    May, N.R.2    Metro, M.J.3
  • 18
    • 0034851036 scopus 로고    scopus 로고
    • Efficacy and safety of Sildenafil citrate for treatment of Erectile Dysfunction in a population with associated organic risk factors
    • Guay AT, Perez JB, Jacobson J, et al.: Efficacy and safety of Sildenafil citrate for treatment of Erectile Dysfunction in a population with associated organic risk factors. J Androl 2001, 22:793-797.
    • (2001) J Androl , vol.22 , pp. 793-797
    • Guay, A.T.1    Perez, J.B.2    Jacobson, J.3
  • 19
    • 0042203611 scopus 로고    scopus 로고
    • Oral testosterone undecanoate reverses erectile dysfunction associated with diabetes mellitus in patients failing on sildenafil citrate therapy alone
    • Kalinchenko SY, Kozlov GI, Gontcharov NP, et al.: Oral testosterone undecanoate reverses erectile dysfunction associated with diabetes mellitus in patients failing on sildenafil citrate therapy alone. Aging Male 2003, 6:94-99.
    • (2003) Aging Male , vol.6 , pp. 94-99
    • Kalinchenko, S.Y.1    Kozlov, G.I.2    Gontcharov, N.P.3
  • 20
    • 35748950112 scopus 로고    scopus 로고
    • Analysis of the impact of androgen deprivation therapy on sildenafil citrate response following radiation therapy for prostate cancer
    • Teloken PE, Ohebshalom M, Mohideen N, et al.: Analysis of the impact of androgen deprivation therapy on sildenafil citrate response following radiation therapy for prostate cancer. J Urol 2007, 178:2521-2525.
    • (2007) J Urol , vol.178 , pp. 2521-2525
    • Teloken, P.E.1    Ohebshalom, M.2    Mohideen, N.3
  • 21
    • 34248150869 scopus 로고    scopus 로고
    • Is sildenafil citrate associated with an amelioration of the symptomatology of androgen decline in the aging male?
    • Koulikov D, Fridmans A, Chertin B, et al.: Is sildenafil citrate associated with an amelioration of the symptomatology of androgen decline in the aging male? J Urol 2007, 177:2267-2271.
    • (2007) J Urol , vol.177 , pp. 2267-2271
    • Koulikov, D.1    Fridmans, A.2    Chertin, B.3
  • 22
    • 14144250622 scopus 로고    scopus 로고
    • Risk factors in predicting a poor response to sildenafil citrate in elderly men with erectile dysfunction
    • Park K, Ku JH, Kim SW, et al.: Risk factors in predicting a poor response to sildenafil citrate in elderly men with erectile dysfunction. BJU Int 2005, 95:366-370.
    • (2005) BJU Int , vol.95 , pp. 366-370
    • Park, K.1    Ku, J.H.2    Kim, S.W.3
  • 23
    • 20644458331 scopus 로고    scopus 로고
    • Sildenafil non responders: Hemodynamic and morphometric studies
    • Wespes E, Rammal A, Garbar C: Sildenafil non responders: hemodynamic and morphometric studies. Eur Urol 2005, 48:136-139.
    • (2005) Eur Urol , vol.48 , pp. 136-139
    • Wespes, E.1    Rammal, A.2    Garbar, C.3
  • 24
    • 22144486277 scopus 로고    scopus 로고
    • Testosterone therapy can enhance erectile function response to sildenafil in patients with PADAM: A pilot study
    • Shamloul R, Ghanem H, Fahmy I, et al.: Testosterone therapy can enhance erectile function response to sildenafil in patients with PADAM: a pilot study. J Sex Med 2005, 2:559-564.
    • (2005) J Sex Med , vol.2 , pp. 559-564
    • Shamloul, R.1    Ghanem, H.2    Fahmy, I.3
  • 25
    • 33745714855 scopus 로고    scopus 로고
    • Combined use of androgen and sildenafil for hypogonadal patients non responsive to sildenafil alone
    • Hwang TI, Chen HE, Tsai TF, et al.: Combined use of androgen and sildenafil for hypogonadal patients non responsive to sildenafil alone. Int J Impot Res 2006, 18:400-404.
    • (2006) Int J Impot Res , vol.18 , pp. 400-404
    • Hwang, T.I.1    Chen, H.E.2    Tsai, T.F.3
  • 26
    • 33644895970 scopus 로고    scopus 로고
    • Testosterone and erectile function in hypogonadal men unresponsive to tadalafil. Results from an open-label uncontrolled study
    • Yassin AA, Saad F, Diede HE: Testosterone and erectile function in hypogonadal men unresponsive to tadalafil. Results from an open-label uncontrolled study. Andrologia 2006, 38:61-66.
    • (2006) Andrologia , vol.38 , pp. 61-66
    • Yassin, A.A.1    Saad, F.2    Diede, H.E.3
  • 27
    • 3142546340 scopus 로고    scopus 로고
    • Randomized study of testosterone gel as adjunctive therapy to sildenafil in hypogonadal men with erectile dysfunction who do not respond to sildenafil alone
    • Shabsigh R, Kaufman JM, Steidle C, Padma-Nathan: Randomized study of testosterone gel as adjunctive therapy to sildenafil in hypogonadal men with erectile dysfunction who do not respond to sildenafil alone. J Urol 2004, 172:658-663.
    • (2004) J Urol , vol.172 , pp. 658-663
    • Shabsigh, R.1    Kaufman, J.M.2    Steidle, C.3    Nathan, P.4
  • 28
    • 4644342381 scopus 로고    scopus 로고
    • Type V phosphodiesterase inhibitor treatments for erectile dysfunction increase testosterone levels
    • Carosa E, Martini P, Brandetti F, et al.: Type V phosphodiesterase inhibitor treatments for erectile dysfunction increase testosterone levels. Clin Endocrinol (Oxf) 2004, 61:382-386.
    • (2004) Clin Endocrinol (Oxf) , vol.61 , pp. 382-386
    • Carosa, E.1    Martini, P.2    Brandetti, F.3
  • 29
    • 33745236862 scopus 로고    scopus 로고
    • Testosterone:estradiol ratio changes with long-term tadalafil administration: A pilot study
    • Greco EA, Pili M, Bruzziches R, et al.: Testosterone:estradiol ratio changes with long-term tadalafil administration: a pilot study. J Sex Med 2006, 3:716-722.
    • (2006) J Sex Med , vol.3 , pp. 716-722
    • Greco, E.A.1    Pili, M.2    Bruzziches, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.