-
1
-
-
28544431635
-
Epilepsy in elderly people
-
Brodie M.J., Kwan P. Epilepsy in elderly people. BMJ (2005) 331 1317 1322.
-
(2005)
BMJ
, vol.331
, pp. 1317-1322
-
-
Brodie, M.J.1
Kwan, P.2
-
2
-
-
34248339245
-
Epidemiology, aetiology, and clinical management of epilepsy in Asia: A systematic review
-
Mac T.L., Tran D.S., Quet F., Odermatt P., Preux P.M., Tan T.C. Epidemiology, aetiology, and clinical management of epilepsy in Asia: a systematic review. Lancet Neurol. (2007) 6 533 543.
-
(2007)
Lancet Neurol.
, vol.6
, pp. 533-543
-
-
Mac, T.L.1
Tran, D.S.2
Quet, F.3
Odermatt, P.4
Preux, P.M.5
Tan, T.C.6
-
3
-
-
0942277083
-
A systematic review of the contribution of qualitative research to the study of quality of life in children and adolescents with epilepsy
-
Mcewan M.J., Espie C.A., Metcalfe J. A systematic review of the contribution of qualitative research to the study of quality of life in children and adolescents with epilepsy. Seizure (2004) 13 3 14.
-
(2004)
Seizure
, vol.13
, pp. 3-14
-
-
McEwan, M.J.1
Espie, C.A.2
Metcalfe, J.3
-
4
-
-
33846875883
-
Factors influencing on quality of life in people with epilepsy
-
Guekht A.B., Mitrokhina T.V., Lebedeva A.V. et al. Factors influencing on quality of life in people with epilepsy. Seizure (2007) 16 128 133.
-
(2007)
Seizure
, vol.16
, pp. 128-133
-
-
Guekht, A.B.1
Mitrokhina, T.V.2
Lebedeva, A.V.3
-
5
-
-
0036265042
-
Refractory epilepsy: A progressive, intractable but preventable condition?
-
Kwan P., Brodie M. Refractory epilepsy: a progressive, intractable but preventable condition? Seizure (2002) 11 77 84.
-
(2002)
Seizure
, vol.11
, pp. 77-84
-
-
Kwan, P.1
Brodie, M.2
-
6
-
-
33745251005
-
New antiepileptic drugs that are second generation to existing antiepileptic drugs
-
Bialer M. New antiepileptic drugs that are second generation to existing antiepileptic drugs. Expert Opin. Investig. Drugs (2006) 15 637 647.
-
(2006)
Expert Opin. Investig. Drugs
, vol.15
, pp. 637-647
-
-
Bialer, M.1
-
7
-
-
33846194013
-
Progress report on new antiepileptic drugs: A summary of the Eigth Eilat Conference (EILAT VIII)
-
Bialer M., Johannessen S.I., Kupferberg H.J., Levy R.H., Perucca E., Tomson T. Progress report on new antiepileptic drugs: a summary of the Eigth Eilat Conference (EILAT VIII). Epilepsy Res. (2007) 73 1 52.
-
(2007)
Epilepsy Res.
, vol.73
, pp. 1-52
-
-
Bialer, M.1
Johannessen, S.I.2
Kupferberg, H.J.3
Levy, R.H.4
Perucca, E.5
Tomson, T.6
-
9
-
-
0033566070
-
Anticonvulsant and sodium channel-blocking properties of novel 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide derivatives
-
Benes J., Parada A., Figueiredo A.A. et al. Anticonvulsant and sodium channel-blocking properties of novel 10,11-dihydro-5H-dibenz[b,f]azepine-5- carboxamide derivatives. J. Med. Chem. (1999) 42 2582 2587.
-
(1999)
J. Med. Chem.
, vol.42
, pp. 2582-2587
-
-
Benes, J.1
Parada, A.2
Figueiredo, A.A.3
-
10
-
-
0032813767
-
Oxcarbazepine: Current status and clinical applications
-
Schachter S.C. Oxcarbazepine: current status and clinical applications. Expert Opin. Investig. Drugs (1999) 8 1103 1112.
-
(1999)
Expert Opin. Investig. Drugs
, vol.8
, pp. 1103-1112
-
-
Schachter, S.C.1
-
11
-
-
3242768230
-
Safety, tolerability, and pharmacokinetic profile of BIA 2-093, a novel putative antiepileptic, in a rising multiple-dose study in young healthy humans
-
Almeida L., Soares-da-Silva P. Safety, tolerability, and pharmacokinetic profile of BIA 2-093, a novel putative antiepileptic, in a rising multiple-dose study in young healthy humans. J. Clin. Pharmacol. (2004) 44 906 918.
-
(2004)
J. Clin. Pharmacol.
, vol.44
, pp. 906-918
-
-
Almeida, L.1
Soares-Da-Silva, P.2
-
12
-
-
1842739967
-
Overview of the clinical pharmacokinetics of oxcarbazepine
-
Flesch G. Overview of the clinical pharmacokinetics of oxcarbazepine. Clin. Drug Investig. (2004) 24 185 203.
-
(2004)
Clin. Drug Investig.
, vol.24
, pp. 185-203
-
-
Flesch, G.1
-
13
-
-
0026660491
-
Determination of the R-(-) and S-(+) enantiomers of the monohydroxylated metabolite of oxcarbazepine in human plasma by enantioselective high-performance liquid chromatography
-
Flesch G., Francotte E., Hell F., Degen P.H. Determination of the R-(-) and S-(+) enantiomers of the monohydroxylated metabolite of oxcarbazepine in human plasma by enantioselective high-performance liquid chromatography. J. Chromatogr. (1992) 581 147 151.
-
(1992)
J. Chromatogr.
, vol.581
, pp. 147-151
-
-
Flesch, G.1
Francotte, E.2
Hell, F.3
Degen, P.H.4
-
14
-
-
0033391871
-
Enantioselective pharmacokinetics of 10-hydroxycarbazepine after oral administration of oxcarbazepine to healthy Chinese subjects
-
Volosov A., Xiaodong S., Perucca E., Yagen B., Sintov A., Bialer M. Enantioselective pharmacokinetics of 10-hydroxycarbazepine after oral administration of oxcarbazepine to healthy Chinese subjects. Clin. Pharmacol. Ther. (1999) 66 547 553.
-
(1999)
Clin. Pharmacol. Ther.
, vol.66
, pp. 547-553
-
-
Volosov, A.1
Xiaodong, S.2
Perucca, E.3
Yagen, B.4
Sintov, A.5
Bialer, M.6
-
16
-
-
0141504128
-
Safety, tolerability and pharmacokinetic profile of BIA 2-093, a novel putative antiepileptic agent, during first administration to humans
-
Almeida L., Soares-da-Silva P. Safety, tolerability and pharmacokinetic profile of BIA 2-093, a novel putative antiepileptic agent, during first administration to humans. Drugs R D (2003) 4 269 284.
-
(2003)
Drugs R D
, vol.4
, pp. 269-284
-
-
Almeida, L.1
Soares-Da-Silva, P.2
-
17
-
-
23944448566
-
Single-dose and steady-state pharmacokinetics of eslicarbazepine acetate (BIA 2-093) in healthy elderly and young subjects
-
Almeida L., Falcão A., Maia J., Mazur D., Gellert M., Soares-da-Silva P. Single-dose and steady-state pharmacokinetics of eslicarbazepine acetate (BIA 2-093) in healthy elderly and young subjects. J. Clin. Pharmacol. (2005) 45 1062 1066.
-
(2005)
J. Clin. Pharmacol.
, vol.45
, pp. 1062-1066
-
-
Almeida, L.1
Falcão, A.2
Maia, J.3
Mazur, D.4
Gellert, M.5
Soares-Da-Silva, P.6
-
18
-
-
0028269416
-
Oxcarbazepine: Mechanisms of action
-
McLean M.J., Schmutz M., Wamil A.W., Olpe H.R., Portet C., Feldmann K.F. Oxcarbazepine: mechanisms of action. Epilepsia (1994) 35 S5 S9.
-
(1994)
Epilepsia
, vol.35
-
-
McLean, M.J.1
Schmutz, M.2
Wamil, A.W.3
Olpe, H.R.4
Portet, C.5
Feldmann, K.F.6
-
19
-
-
0028142808
-
Oxcarbazepine: Preclinical anticonvulsant profile and putative mechanisms of action
-
Schmutz M., Brugger F., Gentsch C., McLean M.J., Olpe H.R. Oxcarbazepine: preclinical anticonvulsant profile and putative mechanisms of action. Epilepsia (1994) 35 S47 S50.
-
(1994)
Epilepsia
, vol.35
-
-
Schmutz, M.1
Brugger, F.2
Gentsch, C.3
McLean, M.J.4
Olpe, H.R.5
-
20
-
-
0141516469
-
Oxcarbazepine: Chemistry, biotransformation, and pharmacokinetics
-
in: Levy, R.H., Mattson, R., Meldrum, B.S., Perucca, E. (. Eds. Lippincott-Williams & Wilkins, Philadelphia, PA, pp.
-
Bialer M. Oxcarbazepine: chemistry, biotransformation, and pharmacokinetics, in : Levy R.H., Mattson R., Meldrum B.S., Perucca E. (Eds Antiepileptic Drugs, Lippincott-Williams & Wilkins, Philadelphia, PA, 2002, pp. 459 465.
-
(2002)
Antiepileptic Drugs
, pp. 459-465
-
-
Bialer, M.1
-
21
-
-
0242663916
-
Role of biological matrices during the analysis of chiral drugs by liquid chromatography
-
Misl'anová C., Hutta M. Role of biological matrices during the analysis of chiral drugs by liquid chromatography. J. Chromatogr. B (2003) 797 91 109.
-
(2003)
J. Chromatogr. B
, vol.797
, pp. 91-109
-
-
Misl'Anová, C.1
Hutta, M.2
-
22
-
-
0035005884
-
Metabolism of two new antiepileptic drugs and their principal metabolites S(+)- and R(-)-10,11-dihydro-10-hydroxy carbamazepine
-
Hainzl D., Parada A., Soares-da-Silva P. Metabolism of two new antiepileptic drugs and their principal metabolites S(+)- and R(-)-10,11-dihydro-10-hydroxy carbamazepine. Epilepsy Res. (2001) 44 197 206.
-
(2001)
Epilepsy Res.
, vol.44
, pp. 197-206
-
-
Hainzl, D.1
Parada, A.2
Soares-Da-Silva, P.3
-
23
-
-
34347211337
-
Simultaneous and enantioselective liquid chromatographic determination of eslicarbazepine acetate, S-licarbazepine, R-licarbazepine and oxcarbazepine in mouse tissue samples using ultraviolet detection
-
Alves G., Figueiredo I., Castel-Branco M., Loureiro A., Falcão A., Caramona M. Simultaneous and enantioselective liquid chromatographic determination of eslicarbazepine acetate, S-licarbazepine, R-licarbazepine and oxcarbazepine in mouse tissue samples using ultraviolet detection. Anal. Chim. Acta (2007) 596 132 140.
-
(2007)
Anal. Chim. Acta
, vol.596
, pp. 132-140
-
-
Alves, G.1
Figueiredo, I.2
Castel-Branco, M.3
Loureiro, A.4
Falcão, A.5
Caramona, M.6
-
24
-
-
33847611166
-
Eslicarbazepine acetate: A double-blind, add-on, placebo-controlled exploratory trial in adult patients with partial-onset seizures
-
Elger C., Bialer M., Cramer J.A., Maia J., Almeida L., Soares-da-Silva P. Eslicarbazepine acetate: a double-blind, add-on, placebo-controlled exploratory trial in adult patients with partial-onset seizures. Epilepsia (2007) 48 497 504.
-
(2007)
Epilepsia
, vol.48
, pp. 497-504
-
-
Elger, C.1
Bialer, M.2
Cramer, J.A.3
Maia, J.4
Almeida, L.5
Soares-Da-Silva, P.6
-
25
-
-
4644301804
-
Progress report on new antiepileptic drugs: A summary of the Seventh Eilat Conference (EILAT VII)
-
Bialer M., Johannessen S.I., Kupferberg H.J., Levy R.H., Perucca E., Tomson T. Progress report on new antiepileptic drugs: a summary of the Seventh Eilat Conference (EILAT VII). Epilepsy Res. (2004) 61 1 48.
-
(2004)
Epilepsy Res.
, vol.61
, pp. 1-48
-
-
Bialer, M.1
Johannessen, S.I.2
Kupferberg, H.J.3
Levy, R.H.4
Perucca, E.5
Tomson, T.6
-
26
-
-
22244461893
-
Effect of food on the pharmacokinetic profile of eslicarbazepine acetate (BIA 2-093)
-
Maia J., Vaz-da-Silva M., Almeida L. et al. Effect of food on the pharmacokinetic profile of eslicarbazepine acetate (BIA 2-093). Drugs R D (2005) 6 201 206.
-
(2005)
Drugs R D
, vol.6
, pp. 201-206
-
-
Maia, J.1
Vaz-Da-Silva, M.2
Almeida, L.3
-
28
-
-
28844495658
-
Validation of a liquid chromatography-mass spectrometry method to assess the metabolism of bupropion in rat everted gut sacs
-
Arellano C., Philibert C., Vachoux C., Woodley J., Houin G. Validation of a liquid chromatography-mass spectrometry method to assess the metabolism of bupropion in rat everted gut sacs. J. Chromatogr. B (2005) 829 50 55.
-
(2005)
J. Chromatogr. B
, vol.829
, pp. 50-55
-
-
Arellano, C.1
Philibert, C.2
Vachoux, C.3
Woodley, J.4
Houin, G.5
-
29
-
-
22844433227
-
Validation of a liquid chromatography-mass spectrometry method to assess the metabolism of dextromethorphan in rat everted gut sacs
-
Arellano C., Philibert C., Dane à Yakan E.N. et al. Validation of a liquid chromatography-mass spectrometry method to assess the metabolism of dextromethorphan in rat everted gut sacs. J. Chromatogr. B (2005) 819 102 113.
-
(2005)
J. Chromatogr. B
, vol.819
, pp. 102-113
-
-
Arellano, C.1
Philibert, C.2
Dane Yakan, À.E.N.3
-
30
-
-
34247472978
-
The metabolism of midazolam and comparison with other CYP enzyme substrates during intestinal absorption: In vitro studies with rat everted gut sacs
-
Arellano C., Philibert C., Vachoux C., Woodley J., Houin G. The metabolism of midazolam and comparison with other CYP enzyme substrates during intestinal absorption: in vitro studies with rat everted gut sacs. J. Pharm. Pharm. Sci. (2007) 10 26 36.
-
(2007)
J. Pharm. Pharm. Sci.
, vol.10
, pp. 26-36
-
-
Arellano, C.1
Philibert, C.2
Vachoux, C.3
Woodley, J.4
Houin, G.5
-
31
-
-
22944434897
-
Quantitative in vivo microdialysis study on the influence of multidrug transporters on the blood-brain barrier passage of oxacarbazepine: Concomitant use of hippocampal monoamines as pharmacodynamic markers for the anticonvulsant activity
-
Clinckers R., Smolders I., Meurs A., Ebinger G., Michotte Y. Quantitative in vivo microdialysis study on the influence of multidrug transporters on the blood-brain barrier passage of oxacarbazepine: concomitant use of hippocampal monoamines as pharmacodynamic markers for the anticonvulsant activity. J. Pharmacol. Exp. Ther. (2005) 314 725 731.
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.314
, pp. 725-731
-
-
Clinckers, R.1
Smolders, I.2
Meurs, A.3
Ebinger, G.4
Michotte, Y.5
-
32
-
-
27244446035
-
A pilot study on brain-to-plasma partition of 10,11-dyhydro-10-hydroxy- 5H-dibenzo(b,f)azepine-5-carboxamide and MDR1 brain expression in epilepsy patients not responding to oxcarbazepine
-
Marchi N., Guiso G., Rizzi M. et al. A pilot study on brain-to-plasma partition of 10,11-dyhydro-10-hydroxy-5H-dibenzo(b,f)azepine-5-carboxamide and MDR1 brain expression in epilepsy patients not responding to oxcarbazepine. Epilepsia (2005) 46 1613 1620.
-
(2005)
Epilepsia
, vol.46
, pp. 1613-1620
-
-
Marchi, N.1
Guiso, G.2
Rizzi, M.3
-
33
-
-
0034892646
-
A microdialysis study of the novel antiepileptic drug levetiracetam: Extracellular pharmacokinetics and effect on taurine in rat brain
-
Tong X., Patsalos P.N. A microdialysis study of the novel antiepileptic drug levetiracetam: extracellular pharmacokinetics and effect on taurine in rat brain. Br. J. Pharmacol. (2001) 133 867 874.
-
(2001)
Br. J. Pharmacol.
, vol.133
, pp. 867-874
-
-
Tong, X.1
Patsalos, P.N.2
-
34
-
-
52649141256
-
A modified surgical procedure for microdialysis probe implantation in the lateral ventricle of a FVB mouse
-
in press.
-
Shen J., Fraga C., Calabrese C., McCarville M.B., Schaiquevich P., Stewart C.F. A modified surgical procedure for microdialysis probe implantation in the lateral ventricle of a FVB mouse. J. Pharm. Sci. (2008) in press.
-
(2008)
J. Pharm. Sci.
-
-
Shen, J.1
Fraga, C.2
Calabrese, C.3
McCarville, M.B.4
Schaiquevich, P.5
Stewart, C.F.6
|