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Volumn 26, Issue 6, 2008, Pages 684-691

Isolation and characterization of novel phenotype CHO cell mutants defective in peroxisome assembly, using ICR191 as a potent mutagenic agent

Author keywords

CHO mutants; Complementation groups; Peroxisome biogenesis; Peroxisome biogenesis disorders; PEX genes; Zellweger syndrome

Indexed keywords

6 CHLORO 9 [3 (2 CHLOROETHYL)AMINOPROPYLAMINO] 2 METHOXYACRIDINE; ASPARAGINE; CELL PROTEIN; COMPLEMENTARY DNA; ENHANCED GREEN FLUORESCENT PROTEIN; GLUTAMIC ACID; NONANOL; PEROXIN; PEROXIN 2; PEROXIN 3; PEROXIN 5; PEROXIN 6; PEROXIN 7; PEROXISOMAL TARGETING SIGNAL 1 PROTEIN; PEROXISOMAL TARGETING SIGNAL 2 PROTEIN; UNCLASSIFIED DRUG;

EID: 52649127919     PISSN: 02636484     EISSN: 10990844     Source Type: Journal    
DOI: 10.1002/cbf.1493     Document Type: Article
Times cited : (9)

References (29)
  • 3
    • 0038394714 scopus 로고    scopus 로고
    • The pathogenic peroxin Pex26p recruits the Pex1p-Pex6p AAA ATPase complexes to peroxisomes
    • Matsumoto N, Tamura S, Fujiki Y. The pathogenic peroxin Pex26p recruits the Pex1p-Pex6p AAA ATPase complexes to peroxisomes. Nat Cell Biol 2003; 5: 454-460.
    • (2003) Nat Cell Biol , vol.5 , pp. 454-460
    • Matsumoto, N.1    Tamura, S.2    Fujiki, Y.3
  • 4
    • 33845358982 scopus 로고    scopus 로고
    • Lessons from peroxisome-deficient Chinese hamster ovary (CHO) cell mutants
    • Fujiki Y, Okumoto K, Kinoshita N, Ghaedi K. Lessons from peroxisome-deficient Chinese hamster ovary (CHO) cell mutants. Biochim Biophys Acta 2006; 1763: 1374-1381.
    • (2006) Biochim Biophys Acta , vol.1763 , pp. 1374-1381
    • Fujiki, Y.1    Okumoto, K.2    Kinoshita, N.3    Ghaedi, K.4
  • 6
    • 0033787313 scopus 로고    scopus 로고
    • Import of peroxisomal matrix and membrane proteins
    • Subramani S, Koller A, Snyder WB. Import of peroxisomal matrix and membrane proteins. Annu Rev Biochem 2000; 69: 399-418.
    • (2000) Annu Rev Biochem , vol.69 , pp. 399-418
    • Subramani, S.1    Koller, A.2    Snyder, W.B.3
  • 7
    • 0022537701 scopus 로고
    • Isolation of animal cell mutants deficient in plasmalogen biosynthesis and peroxisome assembly
    • Zoeller RA, Raetz CRH. Isolation of animal cell mutants deficient in plasmalogen biosynthesis and peroxisome assembly. Proc Natl Acad Sci USA 1986; 83: 5170-5174.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 5170-5174
    • Zoeller, R.A.1    Raetz, C.R.H.2
  • 8
    • 0025342563 scopus 로고
    • Isolation and characterization of Chinese hamster ovary cell mutants defective in assembly of peroxisomes
    • Tsukamoto T, Yokota S, Fujiki Y. Isolation and characterization of Chinese hamster ovary cell mutants defective in assembly of peroxisomes. J Cell Biol 1990; 110: 651-660.
    • (1990) J Cell Biol , vol.110 , pp. 651-660
    • Tsukamoto, T.1    Yokota, S.2    Fujiki, Y.3
  • 10
    • 0026492894 scopus 로고
    • Animal cell mutants represent two complementation groups of peroxisome-defective Zellweger syndrome
    • Shimozawa N, Tsukamoto T, Suzuki Y, Orii T, Fujiki Y. Animal cell mutants represent two complementation groups of peroxisome-defective Zellweger syndrome. J Clin Invest 1992; 90: 1864-1870.
    • (1992) J Clin Invest , vol.90 , pp. 1864-1870
    • Shimozawa, N.1    Tsukamoto, T.2    Suzuki, Y.3    Orii, T.4    Fujiki, Y.5
  • 11
    • 0034733909 scopus 로고    scopus 로고
    • Peroxisome biogenesis and peroxisome biogenesis disorders
    • Fujiki Y. Peroxisome biogenesis and peroxisome biogenesis disorders. FEBS Lett 2000; 476: 42-46.
    • (2000) FEBS Lett , vol.476 , pp. 42-46
    • Fujiki, Y.1
  • 12
    • 0031862579 scopus 로고    scopus 로고
    • PEX12, the pathogenic gene of group III Zellweger syndrome: CDNA cloning by functional complementation on a CHO cell mutant, patient analysis, and characterization of Pex12p
    • Okumoto K, Shimozawa N, Kawai A, et al. PEX12, the pathogenic gene of group III Zellweger syndrome: cDNA cloning by functional complementation on a CHO cell mutant, patient analysis, and characterization of Pex12p. Mol Cell Biol 1998; 18: 4324-4336.
    • (1998) Mol Cell Biol , vol.18 , pp. 4324-4336
    • Okumoto, K.1    Shimozawa, N.2    Kawai, A.3
  • 13
    • 0031962116 scopus 로고    scopus 로고
    • Peroxisome targeting signal type 1 (PTS1) receptor is involved in import of both PTS1 and PTS2: Studies with PEX5-defective CHO cell mutants
    • Otera H, Okumoto K, Tateishi K, et al. Peroxisome targeting signal type 1 (PTS1) receptor is involved in import of both PTS1 and PTS2: studies with PEX5-defective CHO cell mutants. Mol Cell Biol 1998; 18: 388-399.
    • (1998) Mol Cell Biol , vol.18 , pp. 388-399
    • Otera, H.1    Okumoto, K.2    Tateishi, K.3
  • 14
    • 0033617195 scopus 로고    scopus 로고
    • The peroxin Pex14p: CDNA cloning by functional complementation on a Chinese hamster ovary cell mutant, characterization, and functional analysis
    • Shimizu N, Itoh R, Hirono Y, et al. The peroxin Pex14p: cDNA cloning by functional complementation on a Chinese hamster ovary cell mutant, characterization, and functional analysis. J Biol Chem 1999; 274: 12593-12604.
    • (1999) J Biol Chem , vol.274 , pp. 12593-12604
    • Shimizu, N.1    Itoh, R.2    Hirono, Y.3
  • 15
    • 0033134180 scopus 로고    scopus 로고
    • isolation and characterization of novel peroxisome biogenesis-defective Chinese hamster ovary cell mutants using green fluorescent protein
    • Ghaedi K, Kawai A, Okumoto K, et al. isolation and characterization of novel peroxisome biogenesis-defective Chinese hamster ovary cell mutants using green fluorescent protein. Exp Cell Res 1999; 248: 489-497.
    • (1999) Exp Cell Res , vol.248 , pp. 489-497
    • Ghaedi, K.1    Kawai, A.2    Okumoto, K.3
  • 17
    • 0033804750 scopus 로고    scopus 로고
    • PEX3 is the causal gene responsible for peroxisome membrane assembly-defective Zellweger syndrome of complementation group G
    • Ghaedi K, Honsho M, Shimozawa N, Suzuki Y, Kondo N, Fujiki Y. PEX3 is the causal gene responsible for peroxisome membrane assembly-defective Zellweger syndrome of complementation group G. Am J Hum Genet 2000; 67: 976-981.
    • (2000) Am J Hum Genet , vol.67 , pp. 976-981
    • Ghaedi, K.1    Honsho, M.2    Shimozawa, N.3    Suzuki, Y.4    Kondo, N.5    Fujiki, Y.6
  • 18
    • 0036078569 scopus 로고    scopus 로고
    • A novel pex2 mutant: Catalase-deficient but temperature-sensitive PTS1 and PTS2 import
    • Akiyama N, Ghaedi K, Fujiki Y. A novel pex2 mutant: catalase-deficient but temperature-sensitive PTS1 and PTS2 import. Biochem Biophys Res Commun 2002; 293: 1523-1529.
    • (2002) Biochem Biophys Res Commun , vol.293 , pp. 1523-1529
    • Akiyama, N.1    Ghaedi, K.2    Fujiki, Y.3
  • 19
    • 13044312086 scopus 로고    scopus 로고
    • Human PEX19: CDNA cloning by functional complementation, mutation analysis in a patient with Zellweger syndrome and potential role in peroxisomal membrane assembly
    • Matsuzono Y, Kinoshita N, Tamura S, et al. Human PEX19: cDNA cloning by functional complementation, mutation analysis in a patient with Zellweger syndrome and potential role in peroxisomal membrane assembly. Proc Natl Acad Sci USA 1999; 96: 2116-2121.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2116-2121
    • Matsuzono, Y.1    Kinoshita, N.2    Tamura, S.3
  • 20
    • 0026064431 scopus 로고
    • Restoration by a 35K membrane protein of peroxisome assembly in a peroxisome-deficient mammalian cell mutant
    • Tsukamoto T, Miura S, Fujiki Y. Restoration by a 35K membrane protein of peroxisome assembly in a peroxisome-deficient mammalian cell mutant. Nature 1991; 350: 77-81.
    • (1991) Nature , vol.350 , pp. 77-81
    • Tsukamoto, T.1    Miura, S.2    Fujiki, Y.3
  • 21
    • 0034122564 scopus 로고    scopus 로고
    • The peroxin Pex3p initiates membrane assembly in peroxisome biogenesis
    • Ghaedi K, Tamura S, Okumoto K, Matsuzono Y, Fujiki Y. The peroxin Pex3p initiates membrane assembly in peroxisome biogenesis. Mol Biol Cell 2000; 11: 2085-2102.
    • (2000) Mol Biol Cell , vol.11 , pp. 2085-2102
    • Ghaedi, K.1    Tamura, S.2    Okumoto, K.3    Matsuzono, Y.4    Fujiki, Y.5
  • 22
    • 0028845671 scopus 로고
    • Peroxisome assembly factor-2, a putative ATPase cloned by functional complementation on a peroxisome-deficient mammalian cell mutant
    • Tsukamoto T, Miura S, Nakai T, et al. Peroxisome assembly factor-2, a putative ATPase cloned by functional complementation on a peroxisome-deficient mammalian cell mutant. Nat Genet 1995; 11: 395-401.
    • (1995) Nat Genet , vol.11 , pp. 395-401
    • Tsukamoto, T.1    Miura, S.2    Nakai, T.3
  • 23
    • 0037088664 scopus 로고    scopus 로고
    • Intracellular localization, function, and dysfunction of the peroxisome-targeting signal type 2 receptor, Pex7p, in mammalian cells
    • Mukai S, Ghaedi K, Fujiki Y. Intracellular localization, function, and dysfunction of the peroxisome-targeting signal type 2 receptor, Pex7p, in mammalian cells. J Biol Chem 2002; 277: 9548-9561.
    • (2002) J Biol Chem , vol.277 , pp. 9548-9561
    • Mukai, S.1    Ghaedi, K.2    Fujiki, Y.3
  • 24
    • 0024412431 scopus 로고
    • Isolation and characterization of spontaneously occurring mutations at the HPRT locus in V79 Chinese hamster cells
    • Zhang LH, Jenssen D. Isolation and characterization of spontaneously occurring mutations at the HPRT locus in V79 Chinese hamster cells. Mutat Res 1989; 212: 253-262.
    • (1989) Mutat Res , vol.212 , pp. 253-262
    • Zhang, L.H.1    Jenssen, D.2
  • 25
    • 0037427201 scopus 로고    scopus 로고
    • Acridine mutagenesis of zebrafish (Danio rerio)
    • Hampson R, Hughes SM. Acridine mutagenesis of zebrafish (Danio rerio). Mutat Res 2003; 525: 1-9.
    • (2003) Mutat Res , vol.525 , pp. 1-9
    • Hampson, R.1    Hughes, S.M.2
  • 26
    • 0034653705 scopus 로고    scopus 로고
    • Cytotoxicity and mutagenicity of frameshift-inducing agent ICR191 in mismatch repair-deficient colon cancer cells
    • Chen W, Eshleman JRM, Aminoshariae R, et al. Cytotoxicity and mutagenicity of frameshift-inducing agent ICR191 in mismatch repair-deficient colon cancer cells. J Natl Cancer Inst 2001; 92: 480-485.
    • (2001) J Natl Cancer Inst , vol.92 , pp. 480-485
    • Chen, W.1    Eshleman, J.R.M.2    Aminoshariae, R.3
  • 27
    • 0022254143 scopus 로고
    • Frameshift mutagenesis by 9-aminoacridine and ICR191 in Escherichia coli effects of uvrB, recA and lexA mutations and of plasmid pKM101
    • Thomas SM, MacPhee DG. Frameshift mutagenesis by 9-aminoacridine and ICR191 in Escherichia coli effects of uvrB, recA and lexA mutations and of plasmid pKM101. Mutat Res 1985; 151: 49-56.
    • (1985) Mutat Res , vol.151 , pp. 49-56
    • Thomas, S.M.1    MacPhee, D.G.2
  • 28
    • 0031586033 scopus 로고    scopus 로고
    • Isolation and characterization of peroxisome-deficient Chinese hamster ovary cell mutants representing human complementation group III
    • Okumoto K, Bogaki A, Tateishi K, et al. Isolation and characterization of peroxisome-deficient Chinese hamster ovary cell mutants representing human complementation group III. Exp Cell Res 1997; 233: 11-20.
    • (1997) Exp Cell Res , vol.233 , pp. 11-20
    • Okumoto, K.1    Bogaki, A.2    Tateishi, K.3
  • 29
    • 0034647529 scopus 로고    scopus 로고
    • Disruption of interaction of the longer isoform, of Pex5p, Pex5pL, with Pex7p abolishes the PTS2 protein import in mammals: Study with a novel PEX5-impaired Chinese hamster ovary cell mutant
    • Matsumura T, Otera H, Fujiki Y. Disruption of interaction of the longer isoform, of Pex5p, Pex5pL, with Pex7p abolishes the PTS2 protein import in mammals: study with a novel PEX5-impaired Chinese hamster ovary cell mutant. J Biol Chem 2000; 275: 21715-21721.
    • (2000) J Biol Chem , vol.275 , pp. 21715-21721
    • Matsumura, T.1    Otera, H.2    Fujiki, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.