Absorption and tissue distribution of an immunomodulatory α-D-glucan after oral administration of Tricholoma matsutake

Journal of Agricultural and Food Chemistry

Volumn 56, Issue 17, 2008, Pages 7715-7720

  Hoshi, Hirotaka ^a   Iijima, Hiroko ^a   Ishihara, Yoko ^b   Yasuhara, Tadashi ^c   Matsunaga, Kenichi ^a  

^a KUREHA CORPORATION   (Japan)

^b KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c TOKYO UNIVERSITY OF AGRICULTURE   (Japan)

Author keywords

ELISA; Glucan; Mycelium; Polysaccharide; Tricholoma matsutake

Indexed keywords

GLUCAN; IMMUNOLOGIC FACTOR;

AGARICALES; ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BLOOD; C57BL MOUSE; CHEMISTRY; FEMALE; IMMUNOHISTOCHEMISTRY; INTESTINE ABSORPTION; KINETICS; MALE; MOUSE; MYCELIUM; TISSUE DISTRIBUTION;

AGARICALES; ANIMALS; FEMALE; GLUCANS; IMMUNOHISTOCHEMISTRY; IMMUNOLOGIC FACTORS; INTESTINAL ABSORPTION; KINETICS; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MYCELIUM; TISSUE DISTRIBUTION;

MUS; TRICHOLOMA MATSUTAKE;

EID: 52649102488     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf801123k     Document Type: Article

References (23)

1. Hara, M.; Hanaoka, T.; Kobayashi, M.; Otani, T.; Adachi, Y. H.; Montani, A.; Natsukawa, S.; Shaura, K.; Koizumi, Y.; Kasuga, Y.; Matsuzawa, T.; Ikekawa, T.; Sasaki, T.; Tsugane, S. Cruciferous vegetables, mushrooms, and gastrointestinal cancer risks in a multicenter, hospital-based case-control study in Japan. Nutr. Cancer 2003, 46, 138-147.
2. Kim, H. J.; Chang, W. K.; Lee, S. S.; Choi, B. Y. Dietary factors and gastric cancer in Korea: a case-control study. Int. J. Cancer 2002, 97, 531-535.
3. Leung, M. Y. K.; Liu, C.; Zhu, L. F.; Hui, Y. Z.; Yu, B.; Fung, K. P. Chemical and biological characterization of a polysaccharide biological response modifier from Aloe vera L. var. chinensis (Haw.). Berg. Glycobiol. 2004, 14, 501-510.
4. Theuwissen, E.; Mensink, R. P. Simultaneous intake of β-glucan and plant stanol esters affects lipid metabolism in slightly hypercholesterolemic subjects. J. Nutr. 2007, 137, 583-588.
5. Rice, P. J.; Lockhart, B. E.; Barker, L. A.; Adams, E. L.; Ensleey, H. E.; Williams, D. L. Pharmacokinetics of fungal (1-3)-β-D-glucans following intravenous administration in rats. Int. Immunopharmacol. 2004, 4, 1209-1215.
6. Miura, N. N.; Ohno, N.; Adachi, Y.; Aketagawa, J.; Tamura, H.; Tanaka, S.; Yadomae, T. Comparison of the blood clearance of triple- and single-helical scizophyllan in mice. Biol. Pharm. Bull. 1995, 18, 185-189.
7. Sone, Y.; Shibata, S.; Kishida, E.; Misaki, A. Alteration of β-D-glucan from edible mushroom after injection into mouse peritoneal cavity. J. Nutr. Sci. Vitaminol. 1994, 40, 335-341.
8. Suda, M.; Ohno, N.; Adachi, Y.; Yadomae, T. Tissue distribution of intraperitoneally administered (1-3)-β-D-glucan (SSG), a highly branched antitumor glucan, in mice. J. Pharmacobiodyn. 1992, 15, 417-426.
9. Hong, F.; Yan, J.; Baran, J.; Allendorf, D. J.; Hansen, R. D.; Ostroff, G. R.; Xing, P. X.; Cheung, N. K. V.; Ross, G. D. Mechanism by which orally administered β-1,3-glucans enhance the tumorcidal activity of antitumor monoclonal antibodies in murine tumor models. J.Immunol. 2004, 173, 797-806.
10. Rice, P. J.; Adams, E. L.; Ozment-Skeleton, T.; Gonzalez, A. J.; Goldman, M. P.; Lockhart, B. E.; Barker, L. A.; Breuel, K. F.; Deponti, W. K.; Kalbfleish, J. H.; Ensley, H. E.; Brown, G. D.; Gordon, S.; Williams, D. L. Oral delivery and gastrointestinal absorption of soluble glucans stimulate increased resistance to infectious challenge. J. Pharmacol. Exp. Ther. 2005, 314, 1079-1086.
11. Gawronski, M.; Park, J. T.; Magee, A. S.; Conrad, H. Microfibrillar structure of PGG-glucan in aqueous solution as triple-helix aggregates by small angle X-ray scattering. Biopolymers 1999, 50, 569-578.
12. Hiebert, L. M.; Wice, S. M.; Jaques, L. B.; Williams, K. E.; Conly, J. M. Orally administered dextran sulfate is absorbed in HIV-positive individuals. J. Lab. Clin. Med. 1999, 133, 161-170.
13. Lorentsen, K. J.; Hendrix, C. W.; Collins, J. M.; Kornhauser, D. M.; Petty, B. G.; Klecker, R. W.; Flexner, C.; Eckel, R. H.; Lietman, P. S. Dextran sulfate is poorly absorbed after oral administration. Ann. Intern. Med. 1989, 111, 561-566.
14. Ishihara, Y.; Iijima, H.; Yagi, Y.; Matsunaga, K. Enhanced recovery of NK cell activity in mice under restraint stress by the administration of a biological response modifier derived from the mycelia of the basidiomycete Tricholoma matsutake. Stress 2003, 6, 141-148.
15. Ishihara, Y.; Iijima, H.; Yagi, Y.; Hoshi, H.; Matsunaga, K. Inhibition of decrease in natural killer cell activity in repeatedly restraint-stressed mice by a biological response modifier derived from cultured mycelia of the basidiomycete Tricholoma matsutake. Neuroimmunomodulation 2004, 11, 41-48.
16. Hoshi, H.; Iijima, H.; Yagi, Y.; Matsunaga, K.; Ishihara, Y.; Yasuhara, T. Isolation and characterization of a novel immunomodulatory α-glucan-protein complex from the mycelium of Tricholoma matsutake in basidiomycetes. J. Agric. Food Chem. 2005, 53, 8948-8956.
17. Hoshi, H.; Yagi, Y.; Matsunaga, K.; Ishihara, Y.; Yasuhara, T. Development of an enzyme-linked immunosorbent assay to detect an immunomodulatory α-D-glucan-protein complex, MPG-1, in basidiomycete Tricholoma matsutake and related processed foods. J. Agric. Food Chem. 2007, 55, 8508-8515.
18. Matsunaga, K.; Hosokawa, A.; Oohara, M.; Sugita, M.; Harada, M.; Nomoto, K. Direct action of a protein-bound polysaccharide, PSK, on transforming growth factor-β. Immunopharmacology 1998, 40, 219-230.
19. Bolkenius, U.; Hahn, D.; Gressner, A. M.; Breitkopf, K.; Dooley, S.; Wickert, L. Glucocorticoids decreases the bioavailability of TGF-β which leads to a reduced TGF-β signaling in hepatic stellate cells. Biochem. Biophys. Res. Commun. 2004, 325, 1264-1270.
20. Kucharzik, T.; Lugering, N.; Rautenberg, K.; Lugering, A.; Schmidt, M. A.; Stoll, R.; Domschke, W. Role of M cells in intestinal barrier function. Ann. N.Y. Acad. Sci. 2000, 915, 171-83.
21. Walker, W. A. Uptake of antigens: role in gastrointestinal disease. Acta Paediatr. Jpn. 1994, 36, 597-610.
22. Mitsuhashi, S.; Hoshi, H.; Matsunaga, K.; Mitsugi, K.; Sudo, T. Absorption, distribution and excretion of a functional foodstuff (Kureha M6271) derived from mycelia of a basidiomycete Tricholoma matsutake, after oral administration. J. New Rem. Clin. 2003, 52, 840-852.
23. Herre, J.; Willment, J. A.; Gorden, S.; Brown, G. D. The role of dectin-1 in antifungal immunity. Crit. Rev. Immunol. 2004, 24, 193-203.