Simvastatin inhibits catecholamine secretion and synthesis induced by acetylcholine via blocking Na+ and Ca2+ influx in bovine adrenal medullary cells

Journal of Pharmacology and Experimental Therapeutics

Volumn 327, Issue 1, 2008, Pages 130-136

  Matsuda, Taeko ^a   Toyohira, Yumiko ^a   Ueno, Susumu ^a   Tsutsui, Masato ^a   Yanagihara, Nobuyuki ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; HISTAMINE; SIMVASTATIN; SODIUM ION; TYROSINE; VERATRIDINE; VOLTAGE GATED CALCIUM CHANNEL;

ADRENAL MEDULLA; ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CATECHOLAMINE RELEASE; CATECHOLAMINE SYNTHESIS; CATTLE; CELL MEMBRANE TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; IC 50; NONHUMAN; OOCYTE; PRIORITY JOURNAL; SODIUM TRANSPORT; SYMPATHETIC NERVE CELL; XENOPUS LAEVIS;

ACETYLCHOLINE; ADRENAL MEDULLA; ANIMALS; CALCIUM; CALCIUM CHANNELS; CATECHOLAMINES; CATTLE; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; HISTAMINE; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MEVALONIC ACID; RECEPTORS, NICOTINIC; SIMVASTATIN; SODIUM; SODIUM CHANNELS; TYROSINE 3-MONOOXYGENASE; XENOPUS LAEVIS;

EID: 52649092483     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.139659     Document Type: Article

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