Acute Toxicity After Hypofractionated Conformal Radiotherapy for Localized Prostate Cancer: Nonrandomized Contemporary Comparison With Standard Fractionation

International Journal of Radiation Oncology Biology Physics

Volumn 72, Issue 3, 2008, Pages

  Leborgne, Felix ^a   Fowler, Jack ^b  

^a Hospital Italiano Montevideo   (Uruguay)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Acute complications; Hypofractionation; Prostate cancer; Radiotherapy

Indexed keywords

RADIOTHERAPY; TOXICITY; UROLOGY;

ACUTE COMPLICATIONS; CONFORMAL RADIOTHERAPY; EXTERNAL BEAM RADIOTHERAPY; HYPOFRACTIONATED; HYPOFRACTIONATION; LOCALIZED PROSTATE CANCER; PROSTATE CANCERS; URINARY COMPLICATIONS;

DISEASES;

ADULT; ADVERSE OUTCOME; AGED; ARTICLE; CANCER LOCALIZATION; CANCER RADIOTHERAPY; COMPUTER ASSISTED RADIOTHERAPY; CONTROLLED STUDY; DIARRHEA; DYSURIA; EXTERNAL BEAM RADIOTHERAPY; FOLLOW UP; HEMATURIA; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; NOCTURIA; PRIORITY JOURNAL; PROSTATE CANCER; RADIATION DOSE FRACTIONATION; RECTUM HEMORRHAGE; URINARY URGENCY; URINE INCONTINENCE;

EID: 52649083527     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2008.01.023     Document Type: Article

References (35)

1. Brenner D.J., and Hall E.J. Fractionation and protraction for radiotherapy of prostate carcinoma. Int J Radiat Oncol Biol Phys 43 (1999) 1095-1101
2. Fowler J.F., Chappell R.J., and Ritter M.A. Is α/β for prostate tumors really low?. Int J Radiat Oncol Biol Phys 50 (2001) 1021-1031
3. Brenner D.J., Martinez A.A., Edmundson G.K., et al. Direct evidence that prostate tumors show high sensitivity to fractionation (low α/β ratio) comparable to late-responding normal tissue. Int J Radiat Oncol Biol Phys 52 (2002) 6-13
4. Fowler J.F., Chappell R., and Ritter M.A. The prospects for new treatments for prostate cancer. Int J Radiat Oncol Biol Phys 52 (2002) 3-5
5. Brenner J.D. Hypofractionation for prostate cancer radiotherapy: What are the issues?. Int J Radiat Oncol Biol Phys 57 (2003) 912-914
6. Kestin L.L., Goldstein N.S., Vicini F.A., et al. Treatment of prostate cancer with radiotherapy: Should the entire seminal vesicles be included in the clinical target volume?. Int J Radiat Oncol Biol Phys 54 (2002) 680-697
7. Chism D.B., Horwitz E.M., Hanlon A.L., et al. Late morbidity profiles in prostate cancer patients treated to 79-84 Gy by a simple four-field coplanar beam arrangement. Int J Radiat Oncol Biol Phys 55 (2003) 71-77
8. Huang E.H., Pollack A., Levy L., et al. Late rectal toxicity: Dose-volume effects of conformal radiotherapy for prostate cancer. Int J Radiat Oncol Biol Phys 54 (2002) 1314-1321
9. Peeters S.T.H., Lebesque J.V., Heemsbergen W.D., et al. Localized volume effects for late rectal and anal toxicity after radiotherapy for prostate cancer. Int J Radiat Oncol Biol Phys 64 (2006) 1151-1161
10. Cox J.D., Stetz J.A., and Pajak T. Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC). Int J Radiat Oncol Biol Phys 31 (1995) 1341-1346
11. De Meerleer G., Vakaet L., Meersschaout S., et al. Intensity-modulated radiotherapy as primary treatment for prostate cancer: Acute toxicity in 114 patients. Int J Radiat Oncol Biol Phys 60 (2004) 777-787
12. Yeoh E.E., Fraser R.J., McGowan R.E., et al. Evidence for efficacy without increased toxicity of hypofractionated radiotherapy for prostate carcinoma: Early results of a phase III randomized trial. Int J Radiat Oncol Biol Phys 55 (2003) 943-955
13. Yeoh E.E., Holloway R.H., Fraser R.J., et al. Hypofractionated versus conventionally fractionated radiation therapy for prostate carcinoma: Updated results of a phase III randomized trial. Int J Radiat Oncol Biol Phys 66 (2006) 1072-1083
14. Lloyd-Davies R.W., Collins C.D., and Swan A.V. Carcinoma of prostate treated by radical external beam radiotherapy using hypofractionation: Twenty-two years' experience (1962-1984). Urology 36 (1990) 107-111
15. Collins C.D., Lloyd-Davies R.W., and Swan A.V. Radical external beam radiotherapy for localised carcinoma of the prostate using a hypofractionation technique. Clin Oncol (R Coll Radiol) 3 (1991) 127-132
16. Livsey J.E., Cowan R.A., Wylie J.P., et al. Hypofractionated conformal radiotherapy in carcinoma of the prostate: Five-year outcome analysis. Int J Radiat Oncol Biol Phys 57 (2003) 1254-1259
17. Kitamura K., Shirato H., Shinohara N., et al. Reduction in acute morbidity using hypofractionated intensity-modulated radiation therapy assisted with a fluoroscopic real-time tumor-tracking system for prostate cancer: Preliminary results of a phase I/II study. Cancer J 9 (2003) 268-276
18. Lukka H., Hayter C., Julian J.A., et al. Randomized trial comparing two fractionation schedules for patients with localized prostate cancer. J Clin Oncol 23 (2005) 6132-6138
19. Soete G., Arcangeli S., De Meerleer G., et al. Phase II study of a four-week hypofractionated external beam radiotherapy regimen for prostate cancer: Report on acute toxicity. Radiother Oncol 80 (2006) 78-81
20. Loblaw D.A., and Cheung P. External beam irradiation for localized prostate cancer-The promise of hypofractionation. Can J Urol 13 Suppl. 1 (2006) 62-66
21. Higgins G.S., McLaren D.B., Kerr G.R., et al. Outcome analysis of 300 prostate cancer patients treated with neoadjuvant androgen deprivation and hypofractionated radiotherapy. Int J Radiat Oncol Biol 65 (2006) 982-989
22. Junius S., Haustermans K., Bussels B., et al. Hypofractionated intensity modulated irradiation for localized prostate cancer: Results from a phase I/II feasibility study. Radiat Oncol 2 (2007) 29-36
23. Kupelian P.A., Willoughby T.R., Reddy C.A., et al. Hypofractionated intensity-modulated radiotherapy (70 Gy at 2.5 Gy per fraction) for localized prostate cancer: Cleveland Clinic experience. Int J Radiat Oncol Biol Phys 68 (2007) 1424-1430
24. Choi C., Cho C., Kim G., et al. Stereotactic radiation therapy of localized prostate cancer using CyberKnife. [Abstract]. Int J Radiat Oncol Biol 69 (2007) S375
25. Pawlicki T., Kim G.Y., Hsu A., et al. Investigation of LINAC-based image-guided hypofractionated prostate radiotherapy. Med Dosim 32 (2007) 71-79
26. Ryu J.K., Winter K., Michalski J.M., et al. Interim report of toxicity from 3D conformal radiation therapy (3D-CRT) for prostate cancer on 3DOG/RTOG 9406, level III (79.2 Gy). Int J Radiat Oncol Biol 54 (2002) 1036-1046
27. Peeters S.T.H., Heembergen W.D., van Putten W.L.J., et al. Acute and late complications after radiotherapy for prostate cancer: Results of a multicenter randomized trial comparing 68 Gy to 78 Gy. Int J Radiat Oncol Biol 61 (2005) 1019-1034
28. Beckendorf V., Guérif S., Le Prisé E., et al. The GETUG 70 Gy vs. 80 Gy randomized trial for localized prostate cancer: Feasibility and acute toxicity. Int J Radiat Oncol Biol 60 (2004) 1056-1065
29. Eade T.N., Hanlon A.L., Horwitz E.M., et al. What dose of external-beam radiation is high enough for prostate cancer?. Int J Radiat Oncol Biol Phys 68 (2007) 682-689
30. Martin JM, Rosewal TL, Bayley A, et al. Phase II trial of hypofractionated image-guided intensity-modulated radiotherapy for localized prostate adenocarcinoma. Int J Radiat Oncol Biol Phys Epub 2007 July 5.
31. Soete G., Arcangeli S., De Meerleer G., et al. Phase II study of a four-week hypofractionated external beam radiotherapy regimen for prostate cancer: Report on acute toxicity. Radiother Oncol 80 (2006) 78-81
32. Ritter M.A., Forman J.D., Kupelian P.A., et al. A Phase I/II trial of dose-per-fraction escalation for prostate cancer. [Abstract]. Int J Radiat Oncol Biol Phys 69 (2007) S174
33. Pollack A., Hanlon A.L., Horwitz E.M., et al. Dosimetry and preliminary acute toxicity in the first 100 men treated for prostate cancer on a randomized hypofractionation dose escalation trial. Int J Radiat Oncol Biol Phys 64 (2006) 518-526
34. Fowler J.F., Harari P.M., Leborgne F., et al. Acute radiation reactions in oral and pharyngeal mucosa: Tolerable levels in altered fractionation schedules. Radiother Oncol 69 (2003) 161-168
35. Leborgne F., Fowler J.F., Leborgne J.H., et al. Biologically effective doses in medium dose-rate brachytherapy of cancer of the cervix. Radiat Oncol Invest 5 (1997) 289-299