Efficacy of DCBT 2345 - An Ayurvedic compound in treatment of type 2 diabetic patients with secondary failure to oral drugs-randomized double blind placebo control study

International Journal of Diabetes in Developing Countries

Volumn 21, Issue 4, 2001, Pages 176-183

  Mohan, V ^a   Poongothai, S ^a   Deepa, R ^a   Subramanian, S Lakshmi ^a   Nalini, K ^a   Murali, P M ^a  

^a MADRAS DIABETES RESEARCH FOUNDATION   (India)

Author keywords

Ayurvedic compounds; DCBT 2345; Gymnema sylvestre; Syzygium jambolinium and Cephalandra indica; Type 2 diabetes

Indexed keywords

EID: 52549102049     PISSN: 09733930     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. King H, Auberti RE, Herman WH. Global burden of diabetes, 1995 - 2025. Prevalence, numerical estimated and projections. Diabetes Care 1998;2:1414-31
2. Indian Council of Medical Research (ICMR) Collaboration Centre. Flexible dose open trial of Vijayasar in cases of newly diagnosed non-insulin-dependent diabetes mellitus. Indian J. Med. Res 1998;108:24-9
3. Seshaiah V, Sundaram A, Balaji V, Anand Moses. Role of Hyponid in the treatment of non-insulin dependent diabetes mellitus. Indian Journal of Clinical Practice 1998;8:1-5
4. Leatherdale BA, Panesar RK, Singh G, Atkins TW, Bailey CJ, Bignell AH. Improvement in glucose tolerance due to Momordica charantia (Karela). Br. Med. J. Clin Res Ed 1981;282:1823-4
5. Lodha R, Bagga A. Traditional Indian systems of medicine. Ann. Acad. Med. Singapore 2000;29:37-41
6. Viswanathan M, Mohan V, Ramachandran A, Snehalatha C, Anderson JW. Long-term experience with high carbohydrate high fibre diet in Indian patients. Diabetologia Croatia. 1984;13:163-74
7. Baskaran K, Kizar Ahamath B, Radha Shanmugasundaram K, Shanmugasundaram ER. Antidiabetic effect of a leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients. J. Ethnopharmacol. 1990;30:295-300
8. Raj MK. A review on some antidiabetic plants of India. Ancient Science of Life. 1995;XIV:168-80
9. Shanmugasundaram ER, Rajeswari G, Baskaran K, et al. Use of Gymnema sylvestre leaf extract in the control of blood glucose in insulin-dependent diabetes mellitus. J. Ethnopharmacol. 1990;30:281-94
10. Mhaskar KS, Caius JF. A study of Indian medicinal plants II. Gymnema sylvestre R. Br. Indian Medical Research Memoirs. 1930;16:2-75
11. Persaud SJ. Ai-Majed H, Raman A, Jones PM. Gymnema sylvestre stimulates insulin release in vitro by increased membrane permeability. J. Endocrinol. 1999;163:207-12
12. Shimizu K, Ozeki M, Tanaka K, Itoh K, Nakajyo S, Urakawa N, Atsuchi M. Suppression of glucose absorption by extracts from the leaves of Gymnema inodorum. J. Vet. Med. Sci. 1997;59:753-7
13. Kedar P, Chakrabarti CH. Effects of Jambolan seed treatment on blood sugar, lipids and urea on streptozotocin induced diabetes in rabbits. Indian J. Physio. Pharmac. 1983;27:135-40
14. Yoshikawa M, Murakamai T, Kodoya M, Li Y, Murakami N, Yamahara J, Matsuda H. Medicinal food stuffs. IX. The inhibitors of glucose absorption from the leaves of Gymnema sylvestre R. BR (Asclepiadaceae): structures of gymnemosides a and b. Chem. Pharm Bul. (Tokyo). 1997;45:1671-6
15. Teixeira CC, Pinto LP, Kessler FHP, et al. The effect of Syzygium cumini (L) skeels on post-prandial blood glucose levels in non-diabetic rats and rats with streptozotocin - induced diabetes mellitus. J. Ethnopharmacol. 1997;56:209-13
16. Teixeira CC, Rava CA, Mailman da Silva P, et al. Absence of antihyperglycemic effect of jambolan in experimental and clinical models. J. Ethnopharmacol. 2000;71:343-7
17. Shanmugasundaram KR, Panneerselvam C, Sumudram P, Shanmugasundaram ERB. Insulinotropic activity of G. sylvestre, an Indian medicinal herb used in controlling diabetes mellitus. Pharmacol. Res. Commun. 1981;13:475-86