Electronic and resonance effects on the lonization of structural analogues of efavirenz

AAPS Journal

Volumn 3, Issue 4, 2001, Pages

  Rabel, Shelley R ^a   Sun, Sophie ^a   Maurin, Michael B ^a   Patel, Mona ^a  

^a DUPONT COMPANY   (United States)

Author keywords

Benzoxazinone; Carbamate; Efavirenz Analogs; Ionization; PKa; Solubility

Indexed keywords

EID: 52549091935     PISSN: 15507416     EISSN: None     Source Type: Journal    
DOI: 10.1208/ps030428     Document Type: Article

References (4)

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2. Bergon M, Bonafos M, Calmon JP. Kinetics of barban dechlorination in an alkaline medium. Agric Biol Chem. 1980;44:1237-1240.
3. Bergon M, Calmon JP. Structure-reactivity relationships in the hydrolytic degradation of propham, chloropropham, swep and related carbamates. J Agric Food Chem. 1983 ;31:738-743.
4. Carey FA, Sundberg RJ. Advanced Organic Chemistry, 2nd ed. New York: Plenum Press; 1984.