Stability of the oil-in-water type triacylglycerol emulsions

Biotechnology and Bioprocess Engineering

Volumn 6, Issue 4, 2001, Pages 284-288

  Chung, Hesson ^a   Kim, Tae Woo ^a   Kwon, Ick Chan ^a   Jeong, Seo Young ^a  

^a Korea Institute of Science and Technology   (South Korea)

Author keywords

Egg PC; Emulsifier; HLB; Hydrophobicity phosphatidylcholine; Tributyrin; Tricaprin; Tricaproin; Tricaprylin

Indexed keywords

EID: 52549090815     PISSN: 12268372     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02931991     Document Type: Article

References (10)

1. Tanford, C. (1980) The Hydrophobic Effect. 2nd ed., John Wiley, New York, USA.
2. Tardos, T. F. and B. Vincent (1983) Emulsion stability. pp. 129-285. P. Becher (ed.). Encyclopedia of emulsion technology, Volume 1 Basic Theory. Marcel Dekker, Inc., New York, USA.
3. Jumaa, M. and B.W. Müller (1998) The effect of oil components and homogenization conditions on the physicochemical properties and stability of parenteral fat emulsions. Inter. J. Pharm. 163:81-89.
4. Jumaa, M., P. Kleinebudde, and B.W. Müller (1998) Mixture experiments with the oil phase of parenteral emulsions. Eur. J. Pharm. Biopharm. 46:161-167.
5. Ekman, S., A. Derksen, and D. M. Small (1988) The partitioning of fatty acid and cholesterol between core and surfaces of phosphatidylcholine-triolein emulsions at pH 7.4. Biochim. Biophys. Acta 959:343-348.
6. Ishii, F., I. Sasaki, and H. Ogata (1990) Effect of phospholipid emulsifiers on physicochemical properties of intravenous fat emulsions and/or drug carrier emulsions. J. Pharm. Pharmacol. 42:513-515.
7. Sjöstrom, B., B. Bergenståhl, and B. J. Kronberg (1993) A method for the preparation of submicron particles of sparingly water-soluble drugs by precipitation in oil-in-water emulsions: II. Influence of the emulsifier, the solvent, and the drug substance. Pharm. Sci. 82:584-589.
8. Chung, H., T. W. Kim, M. Kwon, I. C. Kwon, and S. Y. Jeong (2001) Oil components modulate physical characteristics and function of the natural oil emulsions as drug or gene delivery system. J. Cont. Rel. 71:339-350.
9. Girifalco, L. A. and R. J. Good (1957) A theory for the estimation of surface and interfacial energies: Part I. Derivation and application to interface tension. J. Phys. Chem. 61:904-909.
10. Yamaguchi, T., K. Nishizaki, S. Itai, H. Hayashi, and H. Ohshima (1995) Physicochemical characterization of parenteral lipid emulsion: Influence of cosurfactants on flocculation and coalescence. Pharm. Res. 12:1273-1278.