An excitatory role for peripheral EP3 receptors in bladder afferent function

American Journal of Physiology - Renal Physiology

Volumn 295, Issue 2, 2008, Pages

  Su, Xin ^a   Lashinger, Erin S R ^a   Leon, Lisa A ^a   Hoffman, Bryan E ^a   Hieble, J Paul ^a   Gardner, Scott D ^a   Fries, Harvey E ^a   Edwards, Richard M ^a   Li, Jun ^a   Laping, Nicholas J ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

Afferent nerve; Bladder distension; Bladder rhythmic contraction; EP3; Viscermotor reflex

Indexed keywords

DG 041; PROSTAGLANDIN E3 RECEPTOR; PROSTAGLANDIN RECEPTOR; PROSTAGLANDIN RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; 3 (1 ((2,4 DICHLOROPHENYL)METHYL) 5 FLUORO 3 METHYL 1H INDOL 7 YL) N ((4,5 DICHLORO 2 THIENYL)SULFONYL) 2 PROPENAMIDE; 3-(1-((2,4-DICHLOROPHENYL)METHYL)-5-FLUORO-3-METHYL-1H-INDOL-7-YL)-N-((4,5-DICHLORO-2-THIENYL)SULFONYL)-2-PROPENAMIDE; ACRYLAMIDE DERIVATIVE; CYCLOPHILIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN EP3 RECEPTOR; SULFONE;

ANIMAL EXPERIMENT; ARTICLE; BLADDER CONTRACTION; BLADDER DISTENSION; BLADDER FUNCTION; CONTROLLED STUDY; CYSTALGIA; DORSAL ROOT; FEMALE; GENE EXPRESSION; MALE; NOCICEPTION; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; SENSORY NERVE; SPONTANEOUSLY HYPERTENSIVE RAT; ANIMAL; BLADDER; COMPARATIVE STUDY; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; HYPERTENSION; INNERVATION; METABOLISM; MUSCLE CONTRACTION; PATHOPHYSIOLOGY; PHYSIOLOGY; SENSORY NERVE CELL; SMOOTH MUSCLE; SPRAGUE DAWLEY RAT; WISTAR KYOTO RAT;

ACRYLAMIDES; ANIMALS; CYCLOPHILINS; DISEASE MODELS, ANIMAL; FEMALE; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HYPERTENSION; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; NEURONS, AFFERENT; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RATS, SPRAGUE-DAWLEY; RECEPTORS, PROSTAGLANDIN E; SULFONES; URINARY BLADDER;

EID: 52449114853     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.90273.2008     Document Type: Article

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