Iron-catalyst-switched selective conjugate addition of grignard reagents: α,β,γ,δ-unsaturated amides as versatile templates for asymmetric three-component coupling processes

Angewandte Chemie - International Edition

Volumn 47, Issue 36, 2008, Pages 6860-6864

  Okada, Satoshi ^a   Arayama, Kyohei ^a   Murayama, Ryuji ^a   Ishizuka, Takumi ^a   Hara, Keiichi ^a   Hirone, Naoki ^a   Hata, Takeshi ^a   Urabe, Hirokazu ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Amides; Asymmetric reaction; Conjugate addition; Grignard reagents; Iron

Indexed keywords

ASYMMETRIC REACTION; CONJUGATE ADDITION; GRIGNARD REAGENTS; IRON;

AMIDES;

AMIDE; IRON;

ALKYLATION; ARTICLE; CATALYSIS; CHEMISTRY; SYNTHESIS;

ALKYLATION; AMIDES; CATALYSIS; IRON;

EID: 52449109396     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200801928     Document Type: Article

References (60)

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60. Although we used a sample of 97%ee for this study, the parent amine of 99%ee is also available. See reference [18].