Overweight patients with severe sleep apnea experience deeper oxygen desaturation at apneic events

Journal of Medical and Dental Sciences

Volumn 55, Issue 1, 2008, Pages 43-47

  Sato, Mitsuo ^a   Suzuki, Masaaki ^b   Suzuki, Jun Ichi ^a   Endo, Yuri ^a   Chiba, Yoshiaki ^a   Matsuura, Masato ^a   Nakagawa, Kenzo ^c   Mataki, Shiro ^a   Kurosaki, Norimasa ^a   Hasegawa, Makoto ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b TEIKYO UNIVERSITY   (Japan)

^c Nakagawa Dental Clinic

Author keywords

Apnea duration; Body mass index; Cardiovascular complication; Hypoxia; Overweight; Sleep apnea syndrome

Indexed keywords

OXYGEN;

ADULT; AGED; ANOXIA; ARTICLE; BLOOD; BODY MASS; CARDIOMYOPATHY; CLASSIFICATION; FEMALE; HUMAN; MALE; MIDDLE AGED; OBESITY; PATHOPHYSIOLOGY; POLYSOMNOGRAPHY; SLEEP APNEA SYNDROME; STATISTICAL MODEL;

ADULT; AGED; AGED, 80 AND OVER; ANOXIA; BODY MASS INDEX; CARDIOMYOPATHIES; FEMALE; HUMANS; LINEAR MODELS; MALE; MIDDLE AGED; OVERWEIGHT; OXYGEN; POLYSOMNOGRAPHY; SLEEP APNEA, OBSTRUCTIVE; YOUNG ADULT;

EID: 52449104138     PISSN: 13428810     EISSN: 13428810     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Marin JM, Carrizo SJ, Vincente E,et al. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet 2005;365:1046-53.
2. Jense HG, Dubin SA, Silverstein PI,et al. Effect of obesity on safe duration of apnea in anesthetized humans. Anesth Analg 1991;72:89-93.
3. Baquet JP, Hammer L, Levy P,et al. The severity of oxygen desaturation is predictive of carotid wall thickening and plaque occurrence. Chest 2005;128:3407-12.
4. Cuttler MJ, Swift NM, Keller DM,et al. Periods of intermittent hypoxic apnea can alter chemoreflex control of sympathetic nerve activity in humans. Am J Physiol Heart Circ Physiol 2004;287: H2054-60.
5. Strohl KP, Altose MD. Oxygen saturation during breath holding and during apnea in sleep. Chest 1984;85:181-6.
6. Nakano H, Ikeda T, Hayashi M. Effect of body mass index on overnight oximetry for the diagnosis of sleep apnea. Respir Med 2004;98:421-7.
7. Wolk R, Shamsuzzaman AS, Sommer VK. Obesity, sleep apnea and hypertension. Hypertension 2003;42:1067-74.
8. Parameswaran K, Todd DC, Soth M. Altered respiratory physiology in obesity. Can Respir J 2006;13:203-10.
9. Watson RA, Pride NB. Postural changes in lung volumes and respiratory resistance in subjects with obesity. J Appl Physiol 2005;98:512-7.