Neurosyphilis: Diagnosis and response to treatment

Clinical Infectious Diseases

Volumn 47, Issue 7, 2008, Pages 900-902

  Musher, Daniel M ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZATHINE PENICILLIN; PENICILLIN G;

CEREBROSPINAL FLUID ANALYSIS; HUMAN; LUMBAR PUNCTURE; NEUROSYPHILIS; NOTE; PREDICTIVE VALIDITY; PRIORITY JOURNAL; REAGIN TEST; SEXUALLY TRANSMITTED DISEASE; SYPHILIS SEROLOGY; TREATMENT RESPONSE; TREPONEMA PALLIDUM HEMAGGLUTINATION TEST; VENEREAL DISEASE REACTION TEST;

HUMANS; NEUROSYPHILIS; SYPHILIS SERODIAGNOSIS;

EID: 52449100142     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/591535     Document Type: Note

References (16)

1. Marra CM, Maxwell CL, Tantalo LC, Sahi SK, Lukehart SA. Normalization of serum RPR titer predicts normalization of cerebrospinal fluid and clinical abnormalities after treatment of neurosyphilis. Clin Infect Dis 2008; 47:893-9 (in this issue).
2. Merritt HH, Adams RD, Solomon HC. Neurosyphilis. Oxford, UK: Oxford University Press, 1946.
3. Moore JE. The modern treatment of syphilis. 2nd ed. Springfield, IL: Charles C. Thomas, 1941.
4. Hooshmand H, Escobar MR, Kopf SW. Neurosyphilis: a study of 241 patients. JAMA 1972; 219:726-9.
5. Jaffe HW, Kabins SA. Examination of cerebrospinal fluid in patients with syphilis. Rev Infec Dis 1982; 4(Suppl):S842-7.
6. Prange HW, Moskophidis M, Schipper HI, Muller F. Relationship between neurological features and intrathecal synthesis of IgG antibodies to Treponema pallidum in untreated and treated human neurosyphilis. J Neurol 1983; 230:241-52.
7. Stokes JH. Modern clinical syphilology: diagnosis-management-case study. Philadelphia: Saunders, 1934.
8. Kampmeier RH. Essentials of syphilology. Philadelphia: Lippincott, 1943.
9. Musher DM, Hamill RJ, Baughn RE. Effect of human immunodeficiency virus (HIV) infection on the course of syphilis and on the response to treatment. Ann Intern Med 1990; 113:872-81.
10. Musher DM. Syphilis, neurosyphilis, penicillin, and AIDS. J Infect Dis 1991; 163:1201-6.
11. Dowell ME, Ross PG, Musher DM, Cate TR, Baughn RE. Response of latent syphilis or neurosyphilis to ceftriaxone therapy in persons infected with human immunodeficiency virus. Am J Med 1992; 93:481-8.
12. Syphilis: modern diagnosis and management. US Department of Health, Education and Welfare, Public Health Service, 1961.
13. Kofman O. The changing pattern of neurosyphilis. Canad Med Assoc J 1956; 74:807-12.
14. Mohr JA, Griffiths W, Jackson R, Saadah H, Bird P, Riddle J. Neurosyphilis and penicillin levels in cerebrospinal fluid. JAMA 1976; 236:2208-9.
15. Polnikorn N, Witoonpanich R, Vorachit M, Vejjajiva S, Vejjajiva A. Penicillin concentrations in the cerebrospinal fluid after benzathine penicillin and probenecid in the treatment of syphilis. Br J Vener Dis 1982; 58:342.
16. Musher DM, Baughn RE. Neurosyphilis in HIV-infected persons. N Engl J Med 1994; 331:1516-7.