Syrian rue tea: A recipe for disaster

Clinical Toxicology

Volumn 46, Issue 8, 2008, Pages 749-752

  Yuruktumen, Aslihan ^a   Karaduman, Sevilay ^a   Bengi, Fecri ^a   Fowler, John ^a  

^a KENT HOSPITAL   (Turkey)

Author keywords

Herbal poisoning; Peganum harmala; Syrian rue

Indexed keywords

GLUCOSE; HALOPERIDOL;

ADULT; AGITATION; ARTICLE; ARTIFICIAL VENTILATION; BLOOD PRESSURE; BODY TEMPERATURE; BREATHING RATE; CASE REPORT; COMATOSE PATIENT; DIAPHORESIS; FEMALE; GLASGOW COMA SCALE; GLUCOSE BLOOD LEVEL; HEART RATE; HUMAN; HYPERTENSION; INTERNATIONAL NORMALIZED RATIO; INTUBATION; KIDNEY FUNCTION TEST; LIVER FUNCTION TEST; MOTOR DYSFUNCTION; NAUSEA; OXYGEN THERAPY; PEGANUM HARMALA; PLANT INTOXICATION; PLANT SEED; SINUS TACHYCARDIA; SOMNOLENCE; TACHYCARDIA; TACHYPNEA; TEA; UNCONSCIOUSNESS; URINALYSIS; VISUAL HALLUCINATION; VOMITING;

ADULT; FEMALE; HUMANS; HYPNOTICS AND SEDATIVES; INTUBATION, INTRATRACHEAL; KIDNEY; LIVER; OVERDOSE; OXYGEN INHALATION THERAPY; PEGANUM; PLANT EXTRACTS; RESPIRATION, ARTIFICIAL; RESPIRATORY MECHANICS; SEEDS; TACHYCARDIA; TREATMENT OUTCOME; UNCONSCIOUSNESS;

ANIMALIA; PEGANUM HARMALA;

EID: 52449098637     PISSN: 15563650     EISSN: 15569519     Source Type: Journal    
DOI: 10.1080/15563650701323205     Document Type: Article

References (22)

1. Hart C, Carpenter B, Reager J, McGinty A. Texas Natural Resource Server Toxic Plant Database. Accessed 5 April 2000, 〈http:// texnat.tamu.edu/ cmplants/toxic/text/AFRICAN.htm〉 (31 January 2007).
2. Davison J, Wargo M. University of Nevada, Cooperative Extension, Publications Page 31 May 2005, 〈http://www.unce.unr.edu/publications/ FS01/FS0145.pdf〉 (31 January 2007).
3. USDA, NRCS. The Plants Database, 1999, 〈http://plants.usda.gov/ plants〉 (31 January 2007).
4. Anonymous. An Indo-European Plant-Teacher, 1986 Gracie and Zarkov Productions, 〈http://www.erowid.org/plants/syrian_rue/syrian_rue_info4. pdf〉 (5 February 2007).
5. Mahmoudian M, Jalilpour, Salehian P. Toxicity of Peganum harmala: review and a case report. Iranian J Pharm Therap 2002; 1:1-4.
6. Salah NB, Amamou M, Jerbi Z, Salah FB, Yacoub M. A case of overdose with Peganum harmala. J Toxicol Clin Exp 1986; 6:319-322.
7. Chen Q, Chao R, Chen H, Hou X, Yan H, Zhou S, Peng W, Xu A. Antitumor and neurotoxic effects of novel harmine derivates and structure-activity relationship analysis. Int J Cancer 2005; 114:675-682.
8. Lamchouri F, Settaf A, Cherrah Y, El Hamidi M, Tligui N, Lyoussi B, Hasar M. Experimental toxicity of Peganum harmala seeds. Ann Pharm Fr 2002; 60:123-129.
9. Lamchouri F, Settaf A, Cherrah Y, Hasar M, Zemzami M, Atif N, Nadori FB, Zaid A, Lyoussi B. In vitro cell-toxicity of Peganum harmala alkoloids on cancerous cell-lines. Fitoterapia 2000; 71:50-54.
10. Riba J, Valle M, Urbano G, Yritia M, Morte A, Barbanoj MJ. Human Pharmacology of ayahuasca: Subjective and cardiovascular effects, monoamine metabolite excretion, and pharmacokinetics. J Pharmacol and Exp Ther 2003; 306(1):73-83.
11. Young LA, Young LG, Klein MM, Klein DM, Beyer D. Recreational Drugs: Everything you need to know about the drugs people take for pleasure today, 20 January 2004, 〈http://www.drugtext.org/library/ books/recreationaldrugs/ syrianrue.htm〉 (31 January 2007).
12. El-Saad El-Rifaie M. Peganum harmala: its use in certain dermatoses. Int J Dermatol 1980; 19:221-222.
13. Brush DE, Bird S, Boyer EW. Monoamine oxidase inhibitor poisoning resulting from internet misinformation on illicit substances. J Toxicol Clin Toxicol 2004; 42:191-195.
14. Kokan L. Monoamine oxidase inhibitors. In: Goldfrank LR, Flomenboum NE, Lewin NA, eds. Toxicologic Emergencies. 7th ed. New York, USA: McGraw-Hill, 2002:885-893.
15. Yu A, Idle JR, Krausz KW, Kupfer A, Gonzales FJ. Contribution of individual cytochrome P450 isozymes to the o-demethylation of the psychotropic β-carboline alkaloids harmaline and harmine, J Pharmacol and Exp Ther 2003; 305(1):315-322.
16. Slotkin TA, DiStefano V, Au WY. Blood levels and urinary excretion of harmine and its metabolites in man and rats. J Pharmacol and Exp Ther 1970; 173:23-30.
17. Glennon RA, Dukat M, Grella B, Hong S, Costantino L, Teitler M, Smith C, Egan C, Davis K, Mattson MV. Binding beta carbolines and related agents at serotonin (5HT (2) and 5HT(1A)), dopamine (D(2)) and benzodiazepine receptors. Drug Alcohol Depend 2000; 60:121-132.
18. Lutes J, Lorden JF, Beales M, Oltmans GA. Tolerance to the tremorogenic effects of harmaline: evidence for altered olivo-cerebellar function. Neuropharmacology 1988; 27:849-855.
19. Husbands SM, Glennon RA, Gorgerat S, Gough R, Tyacke R, Crosby J, Nutt DJ, Lewis JW Hudson AL. Beta-carboline binding to imidazoline receptors. Drug alcohol depend 2001; 64:203-208.
20. Ruiz-Durantez E, Ruiz-Ortega JA, Pineda J, Ugedo L. Stimulatory effect of harmane and other ?-carbolines on locus coeruleus neurons in anaesthetized rats. Neurosci Lett 2001; 308:197-200.
21. Iurlo M, Leone G, Schilstrom B, Linner L, Nomikos G, Hertel P, Silvestrini B, Svensson H. Effects of harmine on dopamine output and metabolism in rat striatum: Role of monoamine oxidase-A inhibition. Psychopharmacology 2001; 159:98-104.
22. Hamouda C, Amamou M, Thabet H, Yacoub M, Hedhili A, Bescharnia F, Ben Salah N, Zhioua M, Abdelmoumen S, El Mekki Ben Brahim N. Plant poisonings from herbal medication admitted to a Tunisian toxicologic intensive care unit, 1983-1998. Vet Hum Toxicol 2000; 42:137-141.