Interruptions of once-daily thoracic radiotherapy do not correlate with outcomes in limited stage small cell lung cancer: Analysis of CALGB phase III trial 9235

Lung Cancer

Volumn 62, Issue 1, 2008, Pages 92-98

  Bogart, Jeffrey A ^a   Watson, Dorothy ^b   McClay, Edward F ^c   Evans, Lisa ^d   Herndon, James E ^b   Laurie, Frances ^e   Seagren, Stephen L ^c   Fitzgerald, T J ^e   Vokes, Everett ^f   Green, Mark R ^d  

^a State University of New York Upstate Medical University: College of Medicine   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Southeast Cancer Control Consortium Inc   (United States)

^e Quality Assurance Review Center   (United States)

^f UNIVERSITY OF CHICAGO   (United States)

Author keywords

Small cell lung cancer; Thoracic radiotherapy; Treatment interruptions

Indexed keywords

CISPLATIN; ETOPOSIDE; TAMOXIFEN;

ADULT; AGED; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER PATIENT; CANCER RADIOTHERAPY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DYSPHAGIA; FEMALE; GRANULOCYTE; HEMATOLOGIC DISEASE; HUMAN; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; MULTIPLE CYCLE TREATMENT; PATIENT ASSESSMENT; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; THROMBOCYTE; TREATMENT DURATION;

ANTINEOPLASTIC AGENTS; COMBINED MODALITY THERAPY; HUMANS; KAPLAN-MEIERS ESTIMATE; LUNG NEOPLASMS; RADIOTHERAPY; SMALL CELL LUNG CARCINOMA; TAMOXIFEN; TREATMENT OUTCOME;

EID: 52349097878     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2008.02.006     Document Type: Article

References (19)

1. Pignon J.P., Arriagada R., Ihde D.C., Johnson D.H., Perry M.C., Souhami R.L., et al. A meta-analysis of thoracic radiotherapy for small-cell lung cancer. N Engl J Med 327 (1992) 1618-1624
2. Warde P., and Payne D. Does thoracic irradiation improve survival and local control in limited-stage small-cell carcinoma of the lung? A meta-analysis. J Clin Oncol 10 (1992) 890-895
3. Movsas B., Moughan J., Komaki R., Choy H., Byhardt R., Langer C., et al. Radiotherapy patterns of care study in lung carcinoma. J Clin Oncol 21 (2003) 4553-4559
4. Langer C., Moughan J., Movsas B., Komaki R., Ettinger D., Owen J., et al. Patterns of care survey (PCS) in lung cancer: how well does current U.S. practice with chemotherapy in the non-metastatic setting follow the literature?. Lung Cancer 48 (2005) 93-102
5. Jeremic B. Patterns of care survey (PCS) in chemotherapy (CHT) in nonmetastatic lung cancer. Lung Cancer 48 (2005) 103-105
6. Takada M., Fukuoka M., Kawahara M., Sugiura T., Yokoyama A., Yokota S., et al. Phase III study of concurrent versus sequential radiotherapy in combination with cisplatin and etoposide for limited-stage small-cell lung cancer: results of the Japan Clinical Oncology Group Study 9104. J Clin Oncol 20 (2002) 3054-3060
7. Turrisi A.T., Kim K., Blum R., Sause W.T., Livingston R.T., Komaki R., et al. Twice-daily compared with once-daily thoracic radiotherapy in limited small-cell lung cancer treated concurrently with cisplatin and etoposide. N Engl J Med 340 (1999) 265-271
8. Videtic G., Fung K., Tomiak A., Stitt L.W., Dar A.R., Truong P.T., et al. Using treatment interruptions to palliate the toxicity from concurrent chemoradiation for limited small cell lung cancer decreases survival and disease control. Lung Cancer 33 (2001) 249-258
9. McClay E.F., Bogart J., Herndon J.E., Watson D., Evans L., Seagren S., et al. A Phase III trial evaluating the combination of cisplatin, etoposide, radiation therapy with or without tamoxifen in patients with limited-stage small cell lung cancer: Cancer and Leukemia Group B Study (9235). Am J Clin Oncol 28 (2005) 81-90
10. Pajak T.F., Laramore G.E., Marcial V.A., Fazekas J.T., Cooper J., Rubin P., et al. Elapsed treatment days-a critical item for radiotherapy quality control review in head and neck trials: RTOG report. Int J Radiat Oncol Biol Phys 20 (1991) 13-20
11. Koukourakis M., Hlouveratsis G., Kosma L., Skarlatos J., Damilakis J., Giatromanolaki A., et al. The impact of overall treatment time on the results of radiotherapy for nonsmall cell carcinoma. Int J Radiat Oncol Biol Phys 34 (1996) 315-322
12. Cox J.D., Pajak T.F., Marcial V.A., Coia L., Mohiuddin N., Fu K.K., et al. Interruptions adversely affect local control and survival with hyperfractionated radiation therapy of carcinomas of the upper respiratory/digestive tracts: New evidence for accelerated proliferation from Radiation Therapy Oncology Group protocol 8313. Cancer 69 (1992) 2744-2748
13. Jeremic B., Shibamoto Y., Milicic B., Dagovic A., Nikolic N., Aleksandrovic J., et al. Impact of treatment interruptions due to toxicity on outcome of patients with early stage (I/II) non-small-cell lung cancer (NSCLC) treated with hyperfractionated radiation therapy alone. Lung Cancer 40 (2003) 317-323
14. Fowler J.F., and Lindstrom M.J. Loss of local control with prolongation in radiotherapy. Int J Radiat Oncol Biol Phys 23 (1992) 457-467
15. Bese N.S., Hendry J., and Jeremic B. Effects of prolongation of overall treatment time due to unplanned interruptions during radiotherapy of different tumor sites and practical methods for compensation. Int J Radiat Oncol Biol Phys 68 (2007) 654-661
16. Bonner J.A., Sloan J.A., Shanahan T.G., Brooks B.T., Marks R.S., Krook J.E., et al. Phase III comparison of twice-daily split-course irradiation versus once-daily irradiation for patients with limited stage small-cell lung carcinoma. J Clin Oncol 17 (1999) 2681-2691
17. Bogart J.A., Herndon J.E., Lyss A.P., Watson D., Miller A.A., Lee M.E., et al. 70 Gy thoracic radiotherapy is feasible concurrent with chemotherapy for limited stage small cell lung cancer: analysis of CALGB 39808. Int J Radiat Oncol Biol Phys 59 (2004) 460-468
18. Fried D.B., Morris D.E., Poole C., Rosenman J.G., Halle J.S., Detterbeck F.C., et al. Systematic review evaluating the timing of thoracic radiation therapy in combined modality therapy for limited-stage small-cell lung cancer. J Clin Oncol 22 (2004) 4837-4845
19. De Ruysscher D., Pijls-Johannesma M., Vansteenkiste J., Kester A., Rutten I., and Lambin P. Systematic review and meta-analysis of randomised, controlled trials of the timing of chest radiotherapy in patients with limited-stage, small-cell lung cancer. Ann Oncol 17 (2006) 543-552