The influence of alpha-fetoprotein on natural suppressor cell activity and Ehrlich carcinoma growth

Korean Journal of Physiology and Pharmacology

Volumn 12, Issue 4, 2008, Pages 193-197

  Belyaev, Nikolai Nikolaevich ^a   Bogdanov, Andrei Yurievich ^a   Savvulidi, Philipp Georgievich ^a   Krasnoshtanov, Vladimir Konstantinovich ^a   Tleulieva, Raikhan Tleulievna ^a   Alipov, Gabit Kaimovich ^a   Sekine, Ichiro ^b   Bae, Jun Sang ^c   Lee, Jeong Beom ^c   Min, Young Ki ^c   Yang, Hun Mo ^c  

^a Kazakhstan Medical University "Higher School of Public Health"   (Kazakhstan)

^b NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^c Soonchunhyang University   (South Korea)

Author keywords

Alpha fetoprotein (AFP); Ehrlich carcinoma (EC); Natural killer cells; Natural suppressor (NS) cells

Indexed keywords

ALPHA FETOPROTEIN; HISTAMINE; INTERLEUKIN 2; INTERLEUKIN 3; TUMOR MARKER;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BONE MARROW CELL; CANCER INHIBITION; CARCINOGENESIS; CBA MOUSE; CELL ACTIVITY; CELL FRACTIONATION; CELL ISOLATION; CELL PROLIFERATION; CELL SUBPOPULATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DENSITY GRADIENT CENTRIFUGATION; DISEASE MARKER; EHRLICH ASCITES TUMOR; IMMUNOMODULATION; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SENSITIVITY ANALYSIS; SUPPRESSOR CELL; TUMOR CELL; TUMOR GROWTH; TUMOR IMMUNITY; TUMOR VOLUME;

EID: 52249123256     PISSN: 12264512     EISSN: None     Source Type: Journal    
DOI: 10.4196/kjpp.2008.12.4.193     Document Type: Article

References (17)

1. Abelev GI. Alpha-fetoprotein biology. In: Skulachev VP ed, Soviet Science Review (section D) Physicochemical Biology. Harwood Acad Publ, New York, p 85-109, 1993
2. Angulo I, Rodriguez R, Garcia B, Medina M, Navarro J, Subiza JL. Involvement of nitric oxide in bone marrow-derived natural suppressor activity. J Immunol 155: 15-26, 1995
3. Belyaev NN, Zakiryanova GK, Khegai LA, Beklemishev AB. Analysis of antimitogenic and histamine binding functions of bone marrow cell isopycnic fractions. Immunology 3: 15-17 1993 (Rus.)
4. Cardoso E, Valdez G, Comini E, Matera L. Effect of human alpha-fetoprotein on native and in vitro-stimulated NK activity. J Clin Lab Immunol 34: 183-188, 1991
5. Carmichael J, DeGraff WG, Gazdar AF, Minna JD, Mitchell JB. Evaluation of a tetrazolium-based semi-automated colorimetric assay: assessment of chemosensitivity testing. Cancer Research 47: 936-942, 1987
6. Chakraborty M, Mandal C. Immuno-supressive effect of human alpha-fetoprotein: a cross species study. Immunol Invest 22: 329-339, 1993
7. Holda, JH, Maier T, Claman HN. Natural suppressor activity in graft-vs-host spleen and normal bone marrow is augmented by IL-2 and interferon-γ. J Immunol 137: 3538-3543, 1986
8. Hoskin DW, Murgita RA. Specific maternal anti-fetal lymphoproliferative responses and their regulation by natural immunosuppressive factors. Clin Exp Immunol 76: 262-267, 1989
9. Moore SC, Theus SA, Barnett JB, Soderberg LS. Cytokine regulation of bone marrow natural suppressor cell activity in the suppression of lymphocyte function. Cell Immunol 141: 398-408, 1992
10. Semeniuk DJ, Boismenu R, Tam J, Weissenhofer W, Murgita RA. Evidence that immunosuppression is an intrinsic property of the alpha-fetoprotein molecule. Adv Exp Med Biol 383: 255-269, 1999
11. Sinenko SA, Belyaev NN, Kuzovlev VD, Khakimzhanov AA. The immunochemical distinctions of human-α fetoprotein preparations as revealed with novel monoclonal antibodies. Reports MS-AS RK 1: 72-80, 1999
12. Subiza JL, Vinuela JE, Rodriguez R, Gil J, Figueredo MA, De la Concha EG. Development of splenic natural suppressor (NS) cells in Ehrlich tumor-bearing mice. Int J Cancer 44: 307-314, 1989
13. Sykes M, Strober S. Mechanisms of tolerance. In: Hematopoietic cell transplantation. 2nd ed. Blackwell Science, Malden, 1999
14. Yamada A, Hayami M. Suppression of natural killer cell activity by chicken alpha-fetoprotein in Japanease quails. J Natl Cancer Inst 70: 735-738, 1983
15. Yamaguchi V, Takashima I, Funakoshi M, Kawami H, Toge T. Defective natural killer activity in gastric cancer patients: possible involvement of suppressor factor receptor. In Vivo 8: 279-283, 1994
16. Young MR, Young ME, Wright MA. Stimulation of immune-suppressive bone marrow cells by colony-stimulated factors. Exp Hematol 18: 806-811, 1990
17. Young MR, Wright MA, Coogan M, Young ME, Bagash J. Tumor-derived cytokines induce bone marrow suppressor cells that mediate immunosuppression through transforming growth factor beta. Cancer Immunol Immunother 35: 14-18, 1992