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Volumn 31, Issue 8-9, 2008, Pages 432-433

Continuous daily dosing of sunitinib in patients with metastatic renal cell cancer

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; DRUG METABOLITE; SU 012662; SUNITINIB; UNCLASSIFIED DRUG;

EID: 52249083726     PISSN: 0378584X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000144179     Document Type: Editorial
Times cited : (4)

References (12)
  • 1
    • 52249112271 scopus 로고    scopus 로고
    • Continuous therapy of sunitinib in patients with metastatic renal cell carcinoma
    • Kahl C HI, Freund M, Casper J: Continuous therapy of sunitinib in patients with metastatic renal cell carcinoma. Onkologie 2008;31:485.
    • (2008) Onkologie , vol.31 , pp. 485
    • Kahl, C.H.1    Freund, M.2    Casper, J.3
  • 2
    • 12244301581 scopus 로고    scopus 로고
    • In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: Determination of a pharmacokinetic/pharmacodynamic relationship
    • Mendel DB, Laird AD, Xin X, et al.: In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship. Clin Cancer Res 2003;9:327-37.
    • (2003) Clin Cancer Res , vol.9 , pp. 327-337
    • Mendel, D.B.1    Laird, A.D.2    Xin, X.3
  • 3
    • 33846181370 scopus 로고    scopus 로고
    • Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
    • Motzer RJ, Hutson TE, Tomczak P, et al.: Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 2007;356:115-24.
    • (2007) N Engl J Med , vol.356 , pp. 115-124
    • Motzer, R.J.1    Hutson, T.E.2    Tomczak, P.3
  • 4
    • 52249084415 scopus 로고    scopus 로고
    • Figlin RA HT, Tomczak P, Michaelson MD, Bukowski RM, Negrier S, Huang X, Kim ST, Chen I, Motzer RJ: Overall survival with sunitinib versus interferon (IFN)-alfa as first-line treatment of metastatic renal cell carcinoma (mRCC). ASCO Annual Meeting Proceedings 2008; Abstr 5024.
    • Figlin RA HT, Tomczak P, Michaelson MD, Bukowski RM, Negrier S, Huang X, Kim ST, Chen I, Motzer RJ: Overall survival with sunitinib versus interferon (IFN)-alfa as first-line treatment of metastatic renal cell carcinoma (mRCC). ASCO Annual Meeting Proceedings 2008; Abstr 5024.
  • 5
    • 33644847440 scopus 로고    scopus 로고
    • Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer
    • Faivre S, Delbaldo C, Vera K, et al.: Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer. J Clin Oncol 2006;24:25-35.
    • (2006) J Clin Oncol , vol.24 , pp. 25-35
    • Faivre, S.1    Delbaldo, C.2    Vera, K.3
  • 6
    • 33947504730 scopus 로고    scopus 로고
    • Sunitinib: From rational design to clinical efficacy
    • Chow LQ, Eckhardt SG: Sunitinib: from rational design to clinical efficacy. J Clin Oncol 2007;25:884-96.
    • (2007) J Clin Oncol , vol.25 , pp. 884-896
    • Chow, L.Q.1    Eckhardt, S.G.2
  • 7
    • 52249102735 scopus 로고    scopus 로고
    • Raymond E FS, Vera K, Delbaldo C, Robert C, Spatz A, Bello C, Brega N, Scigalla P, Armand JP: Final results of a phase I and pharmacokinetic study of SU11248, a novel multi-target tyrosine kinase inhibitor, in patients with advanced cancers. Proc Am Soc Clin Oncol 2003;22:Abstr 769.
    • Raymond E FS, Vera K, Delbaldo C, Robert C, Spatz A, Bello C, Brega N, Scigalla P, Armand JP: Final results of a phase I and pharmacokinetic study of SU11248, a novel multi-target tyrosine kinase inhibitor, in patients with advanced cancers. Proc Am Soc Clin Oncol 2003;22:Abstr 769.
  • 9
    • 19944431093 scopus 로고    scopus 로고
    • A phase 1 study of SU11248 in the treatment of patients with refractory or resistant acute myeloid leukemia (AML) or not amenable to conventional therapy for the disease
    • Fiedler W, Serve H, Dohner H, et al.: A phase 1 study of SU11248 in the treatment of patients with refractory or resistant acute myeloid leukemia (AML) or not amenable to conventional therapy for the disease. Blood 2005;105:986-93.
    • (2005) Blood , vol.105 , pp. 986-993
    • Fiedler, W.1    Serve, H.2    Dohner, H.3
  • 10
    • 52249100212 scopus 로고    scopus 로고
    • Srinivas SRJ, Gillessen S, Harmenberg U, De Mulder PH, Fountzilas G, Vogelzang N, Peschel C, Flodgren P, Escudier B: Continuous daily administration of sunitinib in patients (pts) with cytokine-refractory metastatic renal cell carcinoma (mRCC): Updated results. J Clin Oncol, ASCO Annual Meeting Proceedings Part I 2007;25:Abstr 5040.
    • Srinivas SRJ, Gillessen S, Harmenberg U, De Mulder PH, Fountzilas G, Vogelzang N, Peschel C, Flodgren P, Escudier B: Continuous daily administration of sunitinib in patients (pts) with cytokine-refractory metastatic renal cell carcinoma (mRCC): Updated results. J Clin Oncol, ASCO Annual Meeting Proceedings Part I 2007;25:Abstr 5040.
  • 12
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    • Houk BE BC, Michaelson MD, Bukowski RM, Redman BG, Hudes GR, Wilding G, Motzer RJ. Exposure-response of sunitinib in metastatic renal cell carcinoma (mRCC): A population pharmacokinetic/pharmacodynamic (PKPD) approach. J Clin Oncol, ASCO Annual Meeting Proceedings Part I 2007;25:Abstr 5027.
    • Houk BE BC, Michaelson MD, Bukowski RM, Redman BG, Hudes GR, Wilding G, Motzer RJ. Exposure-response of sunitinib in metastatic renal cell carcinoma (mRCC): A population pharmacokinetic/pharmacodynamic (PKPD) approach. J Clin Oncol, ASCO Annual Meeting Proceedings Part I 2007;25:Abstr 5027.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.