Luteinized thecomas (thecomatosis) of the type typically associated with sclerosing peritonitis: A clinical, histopathologic, and immunohistochemical analysis of 27 cases

American Journal of Surgical Pathology

Volumn 32, Issue 9, 2008, Pages 1273-1290

  Staats, Paul N ^a   McCluggage, W Glenn ^b   Clement, Philip B ^c   Young, Robert H ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b ROYAL GROUP OF HOSPITALS TRUST   (United Kingdom)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Immunohistochemistry; Luteinized thecoma; Ovary; Sclerosing peritonitis

Indexed keywords

ALPHA INHIBIN; BETA CATENIN; CALRETININ; CD34 ANTIBODY; CD56 ANTIGEN; DESMIN; EPITHELIAL MEMBRANE ANTIGEN; ESTROGEN RECEPTOR; INHIBIN; PREDNISONE; PROGESTERONE RECEPTOR; SMOOTH MUSCLE ACTIN; TAMOXIFEN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ABDOMINAL DISTENSION; ABDOMINAL PAIN; ADOLESCENT; ADULT; AGED; ARTICLE; ASCITES; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; EDEMA; FEMALE; FOLLOW UP; HISTOGENESIS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFANT; INTESTINE OBSTRUCTION; MITOSIS; OVARY DISEASE; OVARY FOLLICLE CELL; PRESCHOOL CHILD; SCHOOL CHILD; SCLEROSING PERITONITIS; SPINDLE CELL; THECOMA; METABOLISM; MIDDLE AGED; OVARY TUMOR; PATHOLOGY; PERITONITIS; SCLEROSIS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CHILD; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT; MIDDLE AGED; OVARIAN NEOPLASMS; PERITONITIS; SCLEROSIS; THECOMA;

EID: 52149120069     PISSN: 01475185     EISSN: 15320979     Source Type: Journal    
DOI: 10.1097/PAS.0b013e3181666a5f     Document Type: Article

References (58)

1. Antoniuk P, Tjandra JJ, Lavery IC. Diffuse intra-abdominal fibromatosis in association with bilateral ovarian fibromatosis and oedema. Aust N Z J Surg. 1993;63:315-318.
2. Baiocchi G, Kavanagh JJ, Wharton JT. Endometrioid stromal sarcomas arising from ovarian and extraovarian endometriosis: report of two cases and review of the literature. Gynecol Oncol. 1990;36:147-151.
3. Bhattacharya B, Dilworth HP, Iacobuzio-Donahue C, et al. Nuclear beta-catenin expression distinguishes deep fibromatosis from other benign and malignant fibroblastic and myofibroblastic lesions. Am J Surg Pathol. 2005;29:653-659.
4. Bianco R, de Rosa G, Staibano S, et al. Ovarian luteinized thecoma with sclerosing peritonitis in an adult woman treated with leuprolide and toremifene in complete remission at 5 years. Gynecol Oncol. 2005;96:846-849.
5. Bjorkholm E, Silfversward C. Prognostic factors in granulosa-cell tumors. Gynecol Oncol. 1981;11:261-274.
6. Bolen JW, Hammar SP, McNutt MA. Reactive and neoplastic serosal tissue. A light-microscopic, ultrastructural, and immunocy-tochemical study. Am J Surg Pathol. 1986;10:34-47.
7. Cathro HP, Stoler MH. The utility of calretinin, inhibin, and WT1 immunohistochemical staining in the differential diagnosis of ovarian tumors. Hum Pathol. 2005;36:195-201.
8. Clement PB, Young RH, Hanna W, et al. Sclerosing peritonitis associated with luteinized thecomas of the ovary. A clinicopatho-logical analysis of six cases. Am J Surg Pathol. 1994;18:1-13.
9. Costa MJ, Ames PF, Walls J, et al. Inhibin immunohistochemistry applied to ovarian neoplasms: a novel, effective, diagnostic tool. Hum Pathol. 1997;28:1247-1254.
10. Davila RM, Crouch EC. Role of mesothelial and submesothelial stromal cells in matrix remodeling following pleural injury. Am J Pathol. 1993;142:547-555.
11. del Peso G, Bajo MA, Gil F, et al. Clinical experience with tamoxifen in peritoneal fibrosing syndromes. Adv Perit Dial. 2003;19:32-35.
12. Dudzinski M, Cohen M, Ducatman B. Ovarian malignant luteinized thecoma - an unusual tumor in an adolescent. Gynecol Oncol. 1989;35:104-109.
13. Eltringham WK, Espiner HJ, Windsor CW, et al. Sclerosing peritonitis due to practolol: a report on 9 cases and their surgical management. Br J Surg. 1977;64:229-235.
14. Faber H. Meigs' syndrome with thecomas of both ovaries in a 4-year-old girl. J Pediatr. 1962;61:769-773.
15. Frigerio L, Taccagni GL, Mariani A, et al. Idiopathic sclerosing peritonitis associated with florid mesothelial hyperplasia, ovarian fibromatosis, and endometriosis: a new disorder of abdominal mass. Am J Obstet Gynecol. 1997;176:721-722.
16. Irving JA, McCluggage WG. Ovarian spindle cell lesions: a review with emphasis on recent developments and differential diagnosis. Adv Anat Pathol. 2007;14:305-319.
17. Irving JA, Lerwill MF, Young RH. Gastrointestinal stromal tumors metastatic to the ovary: a report of five cases. Am J Surg Pathol. 2005;29:920-926.
18. Iwasa Y, Minamiguchi S, Konishi I, et al. Sclerosing peritonitis associated with luteinized thecoma of the ovary. Pathol Int. 1996;46:510-514.
19. Jimenez-Heffernan JA, Aguilera A, Aroeira LS, et al. Immunohis-tochemical characterization of fibroblast subpopulations in normal peritoneal tissue and in peritoneal dialysis-induced fibrosis. Virchows Arch. 2004;444:247-256.
20. Khan EM, Pandey R. Sarcoma-like ovarian nodules associated with retractile mesenteritis and retroperitoneal fibrosis. Histopathology. 1994;24:276-278.
21. Lacson AG, Alrabeeah A, Gillis DA, et al. Secondary massive ovarian edema with Meig's syndrome. Am J Clin Pathol. 1989;91: 597-603.
22. Lo WK, Chan KT, Leung AC, et al. Sclerosing peritonitis complicating prolonged use of chlorhexidine in alcohol in the connection procedure for continuous ambulatory peritoneal dialysis. Perit Dial Int. 1991;11:166-172.
23. Margetts PJ, Bonniaud P. Basic mechanisms and clinical implications of peritoneal fibrosis. Perit Dial Int. 2003;23:530-541.
24. Marshall AJ, Baddeley H, Barritt DW, et al. Practolol peritonitis. A study of 16 cases and a survey of small bowel function in patients taking beta adrenergic blockers. Q J Med. 1977;46:135-149.
25. McCluggage WG. Value of inhibin staining in gynecological pathology. Int J Gynecol Pathol. 2001;20:79-85.
26. McCluggage WG. A review and update of morphologically bland vulvovaginal mesenchymal lesions. Int J Gynecol Pathol. 2005;24: 26-38.
27. McCluggage WG, Maxwell P. Immunohistochemical staining for calretinin is useful in the diagnosis of ovarian sex cord-stromal tumours. Histopathology. 2001;38:403-408.
28. McCluggage WG, Maxwell P, Sloan JM. Immunohistochemical staining of ovarian granulosa cell tumors with monoclonal antibody against inhibin. Hum Pathol. 1997;28:1034-1038.
29. McCluggage WG, Patterson A, Maxwell P. Aggressive angio-myxoma of pelvic parts exhibits oestrogen and progesterone receptor positivity. J Clin Pathol. 2000;53:603-605.
30. McCluggage WG, McKenna M, McBride HA. CD56 is a sensitive and diagnostically useful immunohistochemical marker of ovarian sex cord-stromal tumors. Int J Gynecol Pathol. 2007;26: 322-327.
31. Miettinen M, Fetsch JF. Evaluation of biological potential of smooth muscle tumours. Histopathology. 2006;48:97-105.
32. Moustafellos P, Hadjianastassiou V, Roy D, et al. Tamoxifen therapy in encapsulating sclerosing peritonitis in patients after kidney transplantation. Transplant Proc. 2006;38:2913-2914.
33. Movahedi-Lankarani S, Kurman RJ. Calretinin, a more sensitive but less specific marker than alpha-inhibin for ovarian sex cord-stromal neoplasms: an immunohistochemical study of 215 cases. Am J Surg Pathol. 2002;26:1477-1483.
34. Naiki Y, Maeda Y, Matsuo K, et al. Involvement of TGF-beta signal for peritoneal sclerosing in continuous ambulatory peritoneal dialysis. J Nephrol. 2003;16:95-102.
35. Nakayama M, Mitsuhashi T, Shimizu Y, et al. Immunohistochem-ical evaluation of KIT expression in sarcomas of the gynecologic region. Int J Gynecol Pathol. 2006;25:70-76.
36. Nielsen GP, Young RH. Fibromatosis of soft tissue type involving the female genital tract: a report of two cases. Int J Gynecol Pathol. 1997;16:383-386.
37. Nishida T, Ushijima K, Watanabe J, et al. Sclerosing peritonitis associated with luteinized thecoma of the ovary. Gynecol Oncol. 1999;73:167-169.
38. Odama UO, Shih DJ, Korbet SM. Sclerosing peritonitis and systemic lupus erythematosus: a report of two cases. Perit Dial Int. 1999;19:160-164.
39. Oh KH, Margetts PJ. Cytokines and growth factors involved in peritoneal fibrosis of peritoneal dialysis patients. Int J Artif Organs. 2005;28:129-134.
40. Pelkey TJ, Frierson HF Jr, Mills SE, et al. The diagnostic utility of inhibin staining in ovarian neoplasms. Int J Gynecol Pathol. 1998;17:97-105.
41. Pepels MJ, Peters FP, Mebis JJ, et al. Sclerosing peritonitis: an unusual cause of ascites in a patient with systemic lupus erythematosus. Neth J Med. 2006;64:346-349.
42. Raspollini MR, Pinzani P, Simi L, et al. Uterine leiomyosarcomas express KIT protein but lack mutation(s) in exon 9 of c-KIT. Gynecol Oncol. 2005;98:334-335.
43. Reginella RF, Sumkin JH. Sclerosing peritonitis associated with luteinized thecomas. AJR Am J Roentgenol. 1996;167:512-513.
44. Riopel MA, Perlman EJ, Seidman JD, et al. Inhibin and epithelial membrane antigen immunohistochemistry assist in the diagnosis of sex cord-stromal tumors and provide clues to the histogenesis of hypercalcemic small cell carcinomas. Int J Gynecol Pathol. 1998;17: 46-53.
45. Rishi M, Howard LN, Bratthauer GL, et al. Use of monoclonal antibody against human inhibin as a marker for sex cord-stromal tumors of the ovary. Am J Surg Pathol. 1997;21:583-589.
46. Roche WR, du Boulay CE. A case of ovarian fibromatosis with disseminated intra-abdominal fibromatosis. Histopathology. 1989; 14:101-107.
47. Rushing RS, Shajahan S, Chendil D, et al. Uterine sarcomas express KIT protein but lack mutation(s) in exon 11 or 17 of c-KIT. Gynecol Oncol. 2003;91:9-14.
48. Russell P, Robboy SJ, Anderson MC. Ovary: normal and benign conditions. In: Robboy SJ, Anderson MC, Russell P, eds. Pathology of the Female Reproductive Tract. Edinburgh: Churchill Livingstone; 2002:475-526.
49. Schweisguth O, Gerard-Marchant R, Plainfosse B, et al. Bilateral non functionning thecoma of the ovary in epileptic children under anticonvulsant therapy. Acta Paediatr Scand. 1971;60:6-10.
50. Shah VI, Freites ON, Maxwell P, et al. Inhibin is more specific than calretinin as an immunohistochemical marker for differentiating sarcomatoid granulosa cell tumour of the ovary from other spindle cell neoplasms. J Clin Pathol. 2003;56:221-224.
51. Spiegel GW, Swiger FK. Luteinized thecoma with sclerosing peritonitis presenting as an acute abdomen. Gynecol Oncol. 1996;61: 275-281.
52. Stewart CJ, Jeffers MD, Kennedy A. Diagnostic value of inhibin immunoreactivity in ovarian gonadal stromal tumours and their histological mimics. Histopathology. 1997;31:67-74.
53. Tavassoli FA, Devilee P, eds. World Health Organization Classification of Tumors. Pathology and Genetics of the Breast and Female Genital Organs. Lyon: IARC Press; 2003.
54. Werness BA. Luteinized thecoma with sclerosing peritonitis. Arch Pathol Lab Med. 1996;120:303-306.
55. Willis BC, Liebler JM, Luby-Phelps K, et al. Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis. Am J Pathol. 2005;166:1321-1332.
56. Young RH, Scully RE. Fibromatosis and massive edema of the ovary, possibly related entities: a report of 14 cases of fibromatosis and 11 cases of massive edema. Int J Gynecol Pathol. 1984;3: 153-178.
57. Young RH, Prat J, Scully RE. Endometrioid stromal sarcomas of the ovary. A clinicopathologic analysis of 23 cases. Cancer. 1984;53:1143-1155.
58. Young RH, Oliva E, Scully RE. Small cell carcinoma of the ovary, hypercalcemic type. A clinicopathological analysis of 150 cases. Am J Surg Pathol. 1994;18:1102-1116.