Determination of ebastine in pharmaceutical formulations by HPLC

Indian Journal of Pharmaceutical Sciences

Volumn 70, Issue 3, 2008, Pages 406-407

  Prabu, S ^a   Kumar, C ^a   Shirwaikar, A ^a   Shirwaikar, Annie ^a  

^a MANIPAL COLLEGE OF PHARMACEUTICAL SCIENCES   (India)

Author keywords

Ebastine; Reverse phase liquid chromatography; Solid dosage form

Indexed keywords

EBASTINE; METHANOL; WATER;

ACCURACY; ANALYTIC METHOD; ARTICLE; DRUG DETERMINATION; DRUG DOSAGE FORM; DRUG FORMULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SENSITIVITY AND SPECIFICITY; TABLET FORMULATION;

EID: 52149093063     PISSN: 0250474X     EISSN: 19983743     Source Type: Journal    
DOI: 10.4103/0250-474X.43022     Document Type: Article

References (5)

1. Llupia J, Gras J, Llenas J. Comparative antiallergic effects of second-generation H1-antihistamines ebastine, cetirizine and loratadine in preclinical models. Arzneimittel Forschung 2003;53:93-7.
2. Weiner M. Sedation and antihistaminics. Arzneimittel Forschung 1982;32:1193-95.
3. Simons FE, Simons KJ. Clinical pharmacology of new histamine H1 receptor antagonists. Clin Pharmacokinet 1999;36(5):329-52.
4. Kang W, Liu KH, Ryu JY. Simultaneous determination of ebastine and its three metabolites in plasma using liquid chromatography-tandem mass spectrometry. J Chromatogr B 2004;813(1-2):75-80.
5. Rohatagi S, Gillen M, Aubeneau M, Jan C, Pandit B, Jensen BK. Effect of age and gender on the pharmacokinetics of ebastine after single and repeated dosing in healthy subjects. Int J Clin Pharmacol Theor 2001;39(3):126-34.