Hodgkin's lymphoma in a patient of psoriasis treated with long-term, low-dose methotrexate therapy

Indian Journal of Dermatology, Venereology and Leprology

Volumn 74, Issue 4, 2008, Pages 379-382

  Khopkar, Uday ^a   Bhor, Urmila ^a  

^a KEM HOSPITAL   (India)

Author keywords

Chronic treatment; Hodgkin's lymphoma; Low dose methotrexate; Psoriasis

Indexed keywords

BETAMETHASONE DIPROPIONATE; BLEOMYCIN; CLOBETASOL PROPIONATE; DEXAMETHASONE; DOXORUBICIN; METHOTREXATE; MOMETASONE FUROATE; STEROID; VINBLASTINE;

ADULT; ARTICLE; BONE MARROW BIOPSY; BONE MARROW METASTASIS; CASE REPORT; COMBINATION CHEMOTHERAPY; COMPUTER ASSISTED TOMOGRAPHY; DRUG WITHDRAWAL; FEVER; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HODGKIN DISEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; LONG TERM CARE; LOW DRUG DOSE; LYMPH NODE BIOPSY; LYMPHADENOPATHY; MALE; MULTIPLE CYCLE TREATMENT; PSORIASIS VULGARIS;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; DERMATOLOGIC AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; HODGKIN DISEASE; HUMANS; INJECTIONS, INTRAVENOUS; MALE; METHOTREXATE; MIDDLE AGED; PSORIASIS; REMISSION INDUCTION; TOMOGRAPHY, X-RAY COMPUTED;

EID: 52149091484     PISSN: 03786323     EISSN: None     Source Type: Journal    
DOI: 10.4103/0378-6323.42919     Document Type: Article

References (20)

1. Boffa MJ, Chalmers RJ. Methotrexate for psoriasis. Clin Exp Dermatol 1996;21:399-408.
2. Lea AJ. An association between the rheumatic diseases and the reticuloses. Ann Rheum Dis 1964;23:480-4.
3. Banks PM, Witrak GA, Conn DL. Lymphoid neoplasia developing after connective tissue disease. Mayo Clin Proc 1979;54:104-8.
4. Hakulinen T, Isomaki H, Knekt P. Rheumatoid arthritis and cancer studies based linking nationwide registries in Finland. Am J Med 1985;78:29-32.
5. Mariette X, Cazals-Hatem D, Warszawki J, Liote F, Balandraud N, Sibilia J; Investigators of the Club Rhumatismes et Inflammation. Lymphomas in rheumatoid arthritis patients treated with methotrexate: A 3-year prospective study in France. Blood 2002;99:3909-15.
6. Kinlen LJ. Incidence of cancer in rheumatoid arthritis and other disorders after immunosuppressive treatment. Am J Med 1985;78(Suppl 1A):44-49.
7. Starzl TE, Nalesnik MA, Porter KA, Ho M, Iwatsuki S, Griffith BP, et al. Reversibility of lymphomas and lymphoproliferative lesions developing under cyclosporin-steroid therapy. Lancet 1984;1:583-7.
8. Padeh S, Sharon N, Schiby G, Rechavi G, Passwell JH. Hodgkin's lymphoma in systemic onset juvenile rheumatoid arthritis after treatment with low dose methotrexate. J Rheumatol 1997;24:2035-7.
9. Kamel OW, van de Rijn M, Weiss LM, Del Zoppo GJ, Hench PK, Robbins BA, et al. Brief report: reversible lymphomas associated with Epstein-Barr virus occurring during methotrexate therapy for rheumatoid arthritis and dermatomyositis. N Engl J Med 1993;328:1317-21.
10. Moseley AC, Lindsley HB, Skikne BS, Tawfik O. Reversible methotrexate associated lymphoproliferative disease evolving into Hodgkin's disease. J Rheumatol 2000;27:810-3.
11. Jardine DL, Colls BM. Hodgkin's disease following methotrexate therapy for rheumatoid arthritis. N Z Med J 2002;115:293-4.
12. Munro R, Porter DR, Sturrock RD. Lymphadenopathy in a patient with systemic onset juvenile chronic arthritis. Ann Rheum Dis 1998;57:513-7.
13. Bailin PL Tindall JP, Roenigk HH Jr, Hogan MD. Is methotrexate therapy for psoriasis carcinogenic? A modified retrospective-prospective analysis. JAMA 1975;232:359-62.
14. Nyfors A, Jensen H. Frequency of malignant neoplasms in 248 long-term methotrexate-treated psoriatics. A preliminary study. Dermatologica 1983;167:260-1.
15. Stern RS, Zierler S, Parrish JA. Methotrexate used for psoriasis and the risk of noncutaneous or cutaneous malignancy. Cancer 1982;50:869-72.
16. Stern RS. Lymphoma risk in psoriasis. Arch Dermatol 2006;142:1132-5.
17. Hannuksela-Svahn A, Pukkala E, Laara E, Poikolainen K, Karvonen J. Psoriasis, its treatment, and cancer in a cohort of Finnish patients. J Invest Dermatol 2000;114:587-90.
18. Margolis D, Bilker W, Hennessy S, Vittorio C, Santanna J, Strom BL. The risk of malignancy associated with psoriasis. Arch Dermatol 2001;137:778-83.
19. Gelfand JM, Berlin J, van Voorhees A, Margolis DJ. Lymphoma rates are low but increased in patients with psoriasis: results from a population-based cohort study in United Kingdom. Arch Dermatol 2003;139:1425-29.
20. Gelfand JM, Shin DB, Neimann AL, Wang X, Margolis DJ, Troxel AB. The risk of lymphoma in patients with psoriasis. J Invest Dermatol 2006;126:2194-201.