Do additional shaved margins at the time of lumpectomy eliminate the need for re-excision?

American Journal of Surgery

Volumn 196, Issue 4, 2008, Pages 556-558

  Jacobson, Allyson F ^a   Asad, Juhi ^a   Boolbol, Susan K ^a   Osborne, Michael P ^a   Boachie Adjei, Kwadwo ^a   Feldman, Sheldon M ^a  

^a BETH ISRAEL MEDICAL CENTER   (United States)

Author keywords

Breast cancer; Breast conservation; Lumpectomy; Re excision; Shaved margins

Indexed keywords

ADULT; ARTICLE; BREAST CANCER; BREAST CONSERVING SURGERY; BREAST SURGERY; CANCER PATIENT; CARCINOMA IN SITU; CLINICAL DECISION MAKING; ESTHETICS; FEMALE; HUMAN; INTRADUCTAL CARCINOMA; MAJOR CLINICAL STUDY; PARTIAL MASTECTOMY; PRIORITY JOURNAL; REOPERATION; RETROSPECTIVE STUDY; SURGEON; TUMOR VOLUME;

ADULT; BREAST NEOPLASMS; CARCINOMA IN SITU; CARCINOMA, DUCTAL, BREAST; FEMALE; FOLLOW-UP STUDIES; HUMANS; LYMPHATIC METASTASIS; MASTECTOMY, SEGMENTAL; NEOPLASM INVASIVENESS; NEOPLASM RECURRENCE, LOCAL; REOPERATION; RETROSPECTIVE STUDIES; SENTINEL LYMPH NODE BIOPSY;

EID: 52049123315     PISSN: 00029610     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjsurg.2008.06.007     Document Type: Article

References (9)

1. Fisher B., Anderson S., Bryant J., et al. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Engl J Med 347 (2002) 1233-1241
2. Veronesi U., Cascinelli N., Mariani L., et al. Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. N Engl J Med 347 (2002) 1227-1232
3. Gage I., Schnitt S., Nixon A., et al. Pathologic margin involvement and the risk of recurrence in patients treated with breast-conserving therapy. Cancer 78 (1996) 1921-1928
4. Schnitt S., Abner A., Gelman R., et al. The relationship between microscopic margins of resection and the risk of local recurrence in patients with breast cancer treated with breast-conserving surgery and radiation therapy. Cancer 74 (1994) 1746-1751
5. Cao D., Lin C., Woo S.H., et al. Separate cavity margin sampling at the time of initial breast lumpectomy significantly reduces the need for reexcision. Am J Surg Pathol 29 (2005) 1625-1632
6. Huston T., Pigalarga R., Osborne M., and Tousimis E. The influence of additional surgical margins on the total specimen volume excised and the reoperative rate after breast-conserving surgery. Am J Surg 192 (2006) 509-512
7. Keskek M., Kothari M., Ardehali B., et al. Factors predisposing to cavity margin positivity following conservation surgery for breast cancer. Eur J Surg Oncol 30 (2004) 1058-1064
8. O'Sullivan M., Li T., Freedman, and Morrow M. The effect of multiple reexcisions on the risk of local recurrence after breast conserving surgery. Ann Surg Oncol 14 (2007) 3133-3140
9. Early Breast Cancer Trialists' Collaborative Group. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomized trials. Lancet 366 (2005) 2087-2106