Cytotoxic effects and pulpal response caused by a mineral trioxide aggregate formulation and calcium hydroxide

American Journal of Dentistry

Volumn 21, Issue 4, 2008, Pages 255-261

  De Souza Costa, Carlos Alberto ^a,b   Duarte, Paulo Tobias ^c   De Souza, Pedro Paulo Chaves ^d   Giro, Elisa Maria Aparecida ^a   Hebling, Josimeri ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b Department of Physiology and Pathology ^*

^c DEPARTAMENTO DE CIÊNCIAS BIOLÓGICAS   (Brazil)

^d UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM DERIVATIVE; CALCIUM DERIVATIVE; CALCIUM HYDROXIDE; MINERAL TRIOXIDE AGGREGATE; OXIDE; ROOT CANAL FILLING MATERIAL; SILICATE;

ANIMAL; ARTICLE; CELL ADHESION; CELL LINE; CELL MEMBRANE; CHEMICALLY INDUCED DISORDER; CYTOLOGY; CYTOPLASM; DOG; DRUG COMBINATION; DRUG EFFECT; ENDODONTICS; NECROSIS; ODONTOBLAST; PATHOLOGY; SCANNING ELECTRON MICROSCOPY; TIME; TOOTH PULP; TOOTH PULP DISEASE; ULTRASTRUCTURE;

ALUMINUM COMPOUNDS; ANIMALS; CALCIUM COMPOUNDS; CALCIUM HYDROXIDE; CELL ADHESION; CELL LINE; CELL MEMBRANE; CYTOPLASM; DENTAL PULP; DENTAL PULP CALCIFICATION; DENTAL PULP CAPPING; DENTIN, SECONDARY; DOGS; DRUG COMBINATIONS; MICROSCOPY, ELECTRON, SCANNING; NECROSIS; ODONTOBLASTS; OXIDES; PULPOTOMY; ROOT CANAL FILLING MATERIALS; SILICATES; TIME FACTORS;

EID: 52049109646     PISSN: 08948275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Demarco FF, Rosa MS, Tarquínio SBC, Piva E. Influence of the restorative quality on the success of pulpotomy treatment: A preliminary retrospective study. J Appl Oral Sci 2005;13:72-77.
2. Mjör IA. Pulp-dentin biology in restorative dentistry. Part 7: The exposed pulp. Quintessence Int 2002;33:113-135.
3. Holland R, de Souza V, de Mello W, Nery MJ, Bernabé PFE, Otoboni Filho JA. Permeability of the hard tissue bridge formed after pulpotomy with calcium hydroxide: A histologic study. J Am Dent Assoc 1979;99:472-475.
4. Stanley HR. Criteria for standardizing and increasing credibility of direct pulp capping studies. Am J Dent 1998;11:S17-S34.
5. Lopes HP, Estrela C, Elias CN. Comparative study of calcified bridge after pulpotomy and the use of calcium hydroxide associated with different vehicles. Braz Endod J 1996;1:39-43.
6. Higashi T, Okamoto H. Characteristics and effects of calcified degenerative zones on the formation of hard tissue barriers in amputated canine dental pulp. J Endod 1996;22:168-172.
7. Inoue H, Muneyuki H, Izumi T, Taguchi K, Nishigawa Y, Watanabe K, Ohkawa Y, Tamura N. Electron microscopic study on nerve terminals during dentin bridge formation after pulpotomy in dog teeth. J Endod 1997;23:569-571.
8. Hebling J, Giro EMA, Costa CAS. Biocompatibility of an adhesive system applied to human dental pulp. J Endod 1999;25:676-682.
9. Galea-Lauri J, Richardson AJ, Latchmann DS, Katz DR. Increased heat shock protein 90 (hsp90) expression leads to increased apoptosis in the monoblastoid cell line U937 following induction with TNF-a and cycloheximidine. J Immunol 1996;157:4109-4118.
10. Pitt Ford TR, Torabinejad M, Abedi HR, Bakland LK, Kariyawasam SP. Using mineral trioxide aggregate as a pulp-capping material. J Am Dent Assoc 1996;127:1491-1494.
11. Torabinejad M, Chivian N. Clinical applications of mineral trioxide aggregate. J Endod 1999;25:197-205.
12. Faraco Jr. M, Holland R. Response of the pulp of dogs to capping with mineral trioxide aggregate or calcium hydroxide cement. Dent Traumatol 2001;17:163-166.
13. Holland R, de Souza V, Murata SS, Nery MJ, Bernabé PEF, Otoboni Filho JA, Dezan Jr. E. Healing process of dog dental pulp after pulpotomy and pulp covering with mineral trioxide aggregate or portland cement. Braz Dent J 2001;12:109-113.
14. Masuda Y, Wang X, Hossain M, Unno A, Jayawardena JA, Saito K, Nakamura Y, Matsumoto K. Evaluation of biocompatibility of mineral trioxide aggregate with an improved rabbit ear chamber. J Oral Rehabil 2005;32:145-150.
15. Moretton TR, Brown Jr. CE, Legan JJ, Kafrawy AH. Tissue reactions after subcutaneous and intraosseous implantation of mineral trioxide aggregate and ethoxybenzoic acid cement. J Biomed Mater Res 2000;52:528-533.
16. Parirokh M, Asgary S, Eghbal MJ, Stowe S, Eslami B, Eskandarizade A, Shabahang S. A comparative study of white and grey mineral trioxide aggregate as pulp capping agents in dog's teeth. Dent Traumatol 2005;21:150-154.
17. Eidelman E, Holan G, Fuks AB. Mineral trioxide aggregate versus formocresol in pulpotomized primary molars: A preliminary report. Pediatr Dent 2001;23:15-18.
18. Torabinejad M, Higa RK, Mckendry DJ, Pitt Ford TR. Dye leakage of four root end filling materials: Effects of blood contamination. J Endod 1994;20:159-163.
19. Torabinejad M, Rastegar AF, Kettering JD, Pitt Ford TR. Bacterial leakage of mineral trioxide aggregate as a root-end filling material. J Endod 1995;21:109-112.
20. Caliskan MK. Pulpotomy of carious vital teeth with periapical involvement. Int Endod J 1995;28:172-176.
21. Teixeira LS, Demarco FF, Coppola MC, Bonow ML. Clinical and radiographic evaluation of pulpotomies performed under intrapulpal injection of anaesthetic solution. Int Endod J 2001;34:440-446.
22. Morse A. Formic acid-sodium citrate decalcification and butyl alcohol dehydration of teeth and bone sectioning in paraffin. J Dent Res 1945; 24:143-153.
23. Hanks CT, Sun ZL, Fang DN, Edwards CA, Wataha JC, Ritchie HH, Butler WT. Cloned 3T6 cell line from CD-1 mouse fetal molar dental papillae. Connect Tissue Res 1998; 37:1-17.
24. Schröder U. Effects of calcium hydroxide-containing pulp-capping agents on pulp cell migration, proliferation, and differentiation. J Dent Res 1985;64:541-548.
25. Schröder U, Granath LE. Early reaction of intact human teeth to calcium hydroxide following experimental pulpotomy and its significance to the development of hard tissue barrier. Odontol Revy 1971;22:379-396.
26. Yoshiba K.; Yoshiba N, Iwaku M. Histological observations of hard tissue barrier formation in amputated dental pulp capped with tricalcium phosphate containing calcium hydroxide. Endod Dent Traumatol 1994;10:113-120.
27. Subay RK, Susuki S, Susuki S, Haya H, Cox CF. Human pulp response after partial pulpotomy with two calcium hydroxide products. Oral Surg Oral Med Oral Pathol 1995;80:330-337.
28. Murray PE, Lumley PJ, Smith AJ, Ross HF. The influence of sample dimensions on hydroxyl ion release from calcium hydroxide products. Endod Dent Traumatol 2000;16:251-257.
29. Dominguez MS, Witherspoon DE, Gutmann JL, Opperman LA. Histological and scanning electron microscopy assessment of various vital pulp-therapy materials. J Endod 2003;29:324-332.
30. Tziafas D, Pantelidou O, Alvanou A, Belibasakis G, Papadimitriou S. The dentinogenic effect of mineral trioxide aggregate (MTA) in short-term capping axperiments. Int Endod J 2002;35:245-254.
31. Aeinehchi M, Eslami B, Ghanbariha M, Saffar AS. Mineral trioxide aggregate (MTA) and calcium hydroxide as pulp-capping agents in human teeth: A preliminary report. Int Endod J 2003;36:225-231.
32. Torabinejad M, Smith PW, Kettering JD, Pitt Ford TR. Comparative investigation of marginal adaptation of mineral trioxide aggregate and other commonly used root-end filling materials. J Endod 1995;22:295-299.
33. Lee SJ, Monsef M, Torabinejad M. Sealing ability of a mineral trioxide aggregate for repair of lateral root perforations. J Endod 1993;19:541-544.
34. Pitt Ford TR, Torabinejad M, Mckendry DJ, Hong CU, Kariyawasam SP. Use of mineral trioxide aggregate for repair of furcal perforations. Oral Surg Oral Med Oral Pathol 1995;79:756-762.
35. Estrela C, Bammann LL, Estrela CRA, Pécora JD. Antimicrobial and chemical study of MTA, Portland cement, calcium hydroxide paste, Sealapex and Dycal. Braz Dent J 2000;11:3-9.
36. Stowe TJ, Christine M, Stowe B, Fenno JC. The effects of chlorhexidine gluconate (0.12%) on the antimicrobial properties of tooth-colored ProRoot mineral trioxide aggregate. J Endod 2004;30:429-431.
37. Moghaddame-Jafari S, Mantellini MG, Botero TM, McDonald NJ, Nor JE. Effect of ProRoot MTA on pulp cell apoptosis and proliferation in vitro. J Endod 2005;31:387-391.
38. Iwamoto CE, Adachi E, Pameijer CH, Barnes D, Romberg EE, Jefferies S. Clinical and histological evaluation of white ProRoot MTA in direct pulp capping. Am J Dent 2006;19:85-90.
39. Maroto M, Barbería E, Vera V, García-Godoy F. Dentin bridge formation after white mineral trioxide aggregate (white MTA) pulpotomies in primary teeth. Am J Dent 2006;19:75-79.
40. Maroto M, Barbería E, Planells P, García Godoy F. Dentin bridge formation after mineral trioxide aggregate (MTA) pulpotomies in primary teeth. Am J Dent 2005;18:151-154.