The chromosome 11 region from strain 129 provides protection from sex reversal in XYPOS mice

Genetics

Volumn 179, Issue 1, 2008, Pages 419-427

  Nikolova, Ganka ^a   Sinsheimer, Janet S ^a   Eicher, Eva M ^b   Vilain, Eric ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b JACKSON LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHROMOSOME 11; CONGENIC STRAIN; CONTROLLED STUDY; FEMALE; FETUS; FETUS DEVELOPMENT; GENE IDENTIFICATION; GENE LOCUS; GENOME; GONAD DEVELOPMENT; HETEROZYGOSITY; HOMOZYGOSITY; KARYOTYPE 46,XY; MALE; MICROSATELLITE MARKER; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEX DETERMINATION; SEX TRANSFORMATION; SINGLE NUCLEOTIDE POLYMORPHISM; TESTIS DEVELOPMENT; X CHROMOSOME; Y CHROMOSOME; ANIMAL; BIOLOGY; C57BL MOUSE; CHROMOSOME; COMPARATIVE STUDY; GENDER AND SEX; GENETICS; GENOTYPE; GROWTH, DEVELOPMENT AND AGING; METABOLISM; REPRODUCTION; TESTIS;

MUS; MUS MUSCULUS DOMESTICUS;

MICROSATELLITE DNA; PRIMER DNA;

ANIMALS; CHROMOSOMES, MAMMALIAN; COMPUTATIONAL BIOLOGY; DNA PRIMERS; GENOTYPE; MALE; MICE; MICE, INBRED C57BL; MICROSATELLITE REPEATS; POLYMORPHISM, SINGLE NUCLEOTIDE; SEX DETERMINATION (GENETICS); SEX REVERSAL, GONADAL; TESTIS; Y CHROMOSOME;

EID: 52049100868     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.108.088088     Document Type: Article

References (32)

1. ALBRECHT, K. H., and E. M. EICHER, 1997 DNA sequence analysis of Sry alleles (subgenus Mus) implicates misregulation as the cause of C57BL/6J-Y(POS) sex reversal and defines the SRY functional unit. Genetics 147: 1267-1277.
2. ALBRECHT, K. H., M. YOUNG, L. L. WASHBURN and E. M. EICHER, 2003 Sry expression level and protein isoform differences play a role in abnormal testis development in C57BL/6J mice carrying certain Sry alleles. Genetics 164: 277-288.
3. BÉRANGER, F., C. MÉJEAN, B. MONIOT, P. BERTA and M. VANDROMME, 2000 Muscle differentiation is antagonized by SOX15, a new member of the SOX protein family. J. Biol. Chem. 275: 16103-16109.
4. BOWLES, J., L. COOPER, J. BERKMAN and P. KOOPMAN, 1999 Sry requires a CAG repeat domain for male sex determination in Mus musculus. Nat. Genet. 22: 405-408.
5. BULLEJOS, M., and P. KOOPMAN, 2001 Spatially dynamic expression of Sry in mouse genital ridges. Dev. Dyn. 221: 201-205.
6. BULLEJOS, M., and P. KOOPMAN, 2005 Delayed Sry and Sox9 expression in developing mouse gonads underlies B6-Y(DOM) sex reversal. Dev. Biol. 278: 473-481.
7. CARREIRA, S., T. J. DEXTER, U. YAVUZER, D. J. EASTY and C. R. GODING, 1998 Brachyury-related transcription factor Tbx2 and repression of the melanocyte-specific TRP-1 promoter. Mol. Cell. Biol. 18: 5099-5108.
8. CRAWFORD, P. A., C. DORN, Y. SADOVSKY and J. MILBRANDT, 1998 Nuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1. Mol. Cell. Biol. 18: 2949-2956.
9. DE SANTA BARBARA, P., C. MÉ JEAN, B. MONIOT, M. H. MALCLÈS, P. BERTA et al., 2001 Steroidogenic factor-1 contributes to the cyclic-adenosine monophosphate down-regulation of human SRY gene expression. Biol. Reprod. 64: 775-783.
10. EICHER, E. M., and L. L. WASHBURN, 2001 Does one gene determine whether a C57BL/6J-Y(POS) mouse will develop as a female or as an hermaphrodite? J. Exp. Zool. 290: 322-326.
11. EICHER, E. M., L. L. WASHBURN, J. B. WHITNEY, III, and K. E. MORROW, 1982 Mus poschiavinus Y chromosome in the C57BL/6J murine genome causes sex reversal. Science 217: 535-537.
12. EICHER, E. M., L. L. WASHBURN, N. J. SCHORK, B. K. LEE, E. P. SHOWN et al., 1996 Sex-determining genes on mouse autosomes identified by linkage analysis of C57BL/6J-YPOS sex reversal. Nat. Genet. 14: 206-209.
13. FECHNER, P. Y., S. M. MARCANTONIO, V. JASWANEY, G. STETTEN, P. N. GOODFELLOW et al., 1993 The role of the sex-determining region Y gene in the etiology of 46,XX maleness. J. Clin. Endocrinol. Metab. 76: 690-695.
14. HARRELSON, Z., R. J. KELLY, S. N. GOLDIN, J. J. GIBSON-BROWN, R. J. BOLLAG et al., 2004 Tbx2 is essential for patterning the atrioventricular canal and for morphogenesis of the outflow tract during heart development. Development 131: 5041-5052.
15. HAWKINS, J. R., A. TAYLOR, P. BERTA, J. LEVILLIERS, B. VANDERAUWERA et al., 1992 Mutational analysis of Sry - nonsense and missense mutations in XY sex reversal. Hum. Genet. 88: 471-474.
16. JÄGER, R. J., M. ANVRET, K. HALL and G. SCHERER, 1990 A human XY female with a frame shift mutation in the candidate testis-determining gene Sry. Nature 348: 452-454.
17. JESKE, Y. W., J. BOWLES, A. GREENFIELD and P. KOOPMAN, 1995 Expression of a linear Sry transcript in the mouse genital ridge. Nat. Genet. 10: 480-482.
18. KOOPMAN, P., A. MUNSTERBERG, B. CAPEL, N. VIVIAN and R. LOVELL-BADGE, 1990 Expression of a candidate sex-determining gene during mouse testis differentiation. Nature 348: 450-452.
19. KOOPMAN, P., J. GUBBAY, N. VIVIAN, P. GOODFELLOW and R. LOVELL-BADGE, 1991 Male development of chromosomally female mice transgenic for Sry. Nature 351: 117-121.
20. LEE, C. H., and T. TAKETO, 1994 Normal onset, but prolonged expression, of Sry gene in the B6.YDOM sex-reversed mouse gonad. Dev. Biol. 165: 442-452.
21. LEE, C. H., and T. TAKETO, 2001 Low levels of Sry transcripts cannot be the sole cause of B6-Y(TIR) sex reversal. Genesis 30: 7-11.
22. LEE, H. J., W. GORING, M. OCHS, C. MUHLFELD, G. STEDING et al., 2004 Sox15 is required for skeletal muscle regeneration. Mol. Cell. Biol. 24: 8428-8436.
23. LOVELL-BADGE, R., and E. ROBERTSON, 1990 XY female mice resulting from a heritable mutation in the primary testis-determining gene, Tdy. Development 109: 635-646.
24. NEF, S., O. SCHAAD, N. R. STALLINGS, C. R. CEDERROTH, J. L. PITETTI et al., 2005 Gene expression during sex determination reveals a robust female genetic program at the onset of ovarian development. Dev. Biol. 87: 361-377.
25. ROSS, A. J., and B. CAPEL, 2005 Signaling at the crossroads of gonad development. Trends Endocrinol. Metab. 16: 19-25.
26. SARRAJ, M. A., H. P. WILMORE, P. J. MCCLIVE and A. H. SINCLAIR, 2003 Sox15 is up regulated in the embryonic mouse testis. Gene Expr. Patterns 3: 413-417.
27. SCHMIDT, D., C. E. OVITT, K. ANLAG, S. FEHSENFELD, L. GREDSTED et al., 2004 The murine winged-helix transcription factor Foxl2 is required for granulosa cell differentiation and ovary maintenance. Development 131: 933-942.
28. SHAWLOT, W., and R. R. BEHRINGER, 1995 Requirement for Lim1 in head-organizer function. Nature 374: 425-430.
29. SINCLAIR, A. H., P. BERTA, M. S. PALMER, J. R. HAWKINS, B. L. GRIFFITHS et al., 1990 A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif. Nature 346: 240-244.
30. THEILER, K., 1989 The House Mouse: Atlas Of Embryonic Development. Springer-Verlag, New York.
31. VAINIO, S., M. HEIKKILA, A. KISPERT, A., N. CHIN and A. P. MCMAHON, 1999 Female development in mammals is regulated by Wnt-4 signaling. Nature 397: 405-409.
32. WHITNEY, J. B., T. M. MILLS, R. W. LEWIS, R. WARTELL and T. O. ABNEY, 2000 A single genetic determinant that prevents sex reversal in C57BL-YPOS congenic mice. Biochem. Genet. 38: 119-137.