Protective effect of Ginkgolids (A + B) is associated with inhibition of NIK/IKK/IκB/NF-κB signaling pathway in a rat model of permanent focal cerebral ischemia

Brain Research

Volumn 1234, Issue , 2008, Pages 8-15

  Wang, Xuan ^a,d   Qin, Zheng Hong ^a   Shi, Hong ^c   Savitz, Sean Isaac ^b   Qin, Ai Ping ^a   Jiang, Yan ^b   Zhang, Hui Ling ^a,b  

^a MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c INSTITUTE OF MATERIA MEDICA   (China)

^d Shanghai Putuo District People's Hospital ^*  (China)

Author keywords

Ginkgolids (A + B); Ischemia; Neuroprotection; NF B; NIK IKK

Indexed keywords

GINKGOLIDE A; GINKGOLIDE AB; GINKGOLIDE B; GINKGOLIDE DERIVATIVE; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MYC PROTEIN; NUCLEAR FACTOR KAPPA B INDUCING KINASE; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG MECHANISM; INHIBITION KINETICS; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NEUTROPHIL; NONHUMAN; ONCOGENE C MYC; PLEURA; PRIORITY JOURNAL; RAT;

ANIMALS; BLOTTING, WESTERN; BRAIN ISCHEMIA; CEREBRAL CORTEX; DOWN-REGULATION; GENE EXPRESSION; GENES, MYC; GINKGOLIDES; I-KAPPA B KINASE; I-KAPPA B PROTEINS; IMMUNOHISTOCHEMISTRY; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; NEUROPROTECTIVE AGENTS; NF-KAPPA B; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSLOCATION, GENETIC;

RATTUS;

EID: 52049093687     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.07.102     Document Type: Article

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