Fully integrated glass microfluidic device for performing high-efficiency capillary electrophoresis and electrospray ionization mass spectrometry

Analytical Chemistry

Volumn 80, Issue 18, 2008, Pages 6881-6887

  Mellors, J S ^a   Gorbounov, V ^a   Ramsey, R S ^a   Ramsey, J M ^a  

^a University of North Carolina at Chapel Hill   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; CAPILLARY ELECTROPHORESIS; CLADDING (COATING); ELECTROOSMOSIS; ELECTROPHORESIS; FABRICATION; FUSED SILICA; GLASS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDRAULIC DRIVES; INTEGRATED CIRCUITS; IONIZATION; MASS SPECTROMETERS; MASS SPECTROMETRY; MICROFABRICATION; MONOLITHIC INTEGRATED CIRCUITS; NANOFLUIDICS; PEPTIDES; PESTICIDES; PROTEINS; SENSITIVITY ANALYSIS; SEPARATION; SILICA; SILICATE MINERALS; SILICON COMPOUNDS; SPECTROMETERS; SPECTROMETRY; SPRAYING;

ELECTRO SPRAYING; ELECTRO-OSMOTIC FLOW; ELECTROKINETIC; ELECTROSPRAY IONIZATION MASS SPECTROMETRY; EXTERNAL PRESSURES; FULLY INTEGRATED; FUSED-SILICA CAPILLARIES; HIGH-EFFICIENCY; HIGHLY EFFICIENT; HYDRAULIC PUMPING; MICRO-FLUIDIC DEVICES; MONOLITHICALLY INTEGRATED; NANOSPRAY; POSITIVELY CHARGED; SEPARATION CHANNELS; SPRAY TIPS; SURFACE INTERACTIONS;

ELECTROSPRAY IONIZATION;

GLASS;

ARTICLE; CAPILLARY ELECTROPHORESIS; DEVICE; ELECTROSPRAY MASS SPECTROMETRY; MASS SPECTROMETER; MATERIAL COATING; MICROCHIP ANALYSIS; MICROFLUIDICS; OSMOSIS; PROTEIN ANALYSIS; PROTEIN INTERACTION; SENSITIVITY AND SPECIFICITY; SEPARATION TECHNIQUE; SURFACE PROPERTY;

ADSORPTION; ANIMALS; CATTLE; ELECTROPHORESIS, CAPILLARY; GLASS; MICROFLUIDIC ANALYTICAL TECHNIQUES; PEPTIDES; PROTEINS; PROTEOMICS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SURFACE PROPERTIES;

EID: 51949107286     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac800428w     Document Type: Article

References (45)

1. Kutter, J. P., Fintschenko, Y., Eds. Separation Methods in Microanalytical Systems; CRC Press Taylor and Francis Group: Boca Raton FL, 2006.
2. Johnson, M. E.; Landers, J. P. Electrophoresis 2004, 25, 3513-3527.
3. Smyth, W. F.; Brooks, P. Electrophoresis 2004, 25, 1413-1446.
4. Postle, A. D. Lipid Technol. 2006, 18, 181-185.
5. Smith, R. D. BioTechniques 2006, 41, 147-148.
6. Valaskovic, G. A.; Kelleher, N. L.; Little, D. P.; Aaserud, D. J.; Mclafferty, F. W. Anal. Chem. 1995, 67, 3802-3805.
7. Wilm, M.; Mann, M. Anal. Chem. 1996, 68, 1-8.
8. Akashi, S.; Suzuki, K.; Arai, A.; Yamada, N.; Suzuki, E.; Hirayama, K.; Nakamura, S.; Nishimura, Y. Rapid Commun. Mass Spectrom. 2006, 20, 1932-1938.
9. Bings, N. H.; Wang, C.; Skinner, C. D.; Colyer, C. L.; Thibault, P.; Harrison, D. J. Anal. Chem. 1999, 71, 3292.
10. Deng, Y.; Henion, J.; Li, J.; Thibault, P.; Wang, C.; Harrison, D. J. Anal. Chem. 2001, 73, 639-646.
11. Figeys, D.; Aebersold, R. Anal. Chem. 1998, 70, 3721.
12. Figeys, D.; Gygi, S. P.; McKinnon, G.; Aebersold, R. Anal. Chem. 1998, 70, 3728.
13. Figeys, D.; Lock, C.; Taylor, L.; Aebersold, R. Rapid Commun. Mass Spectrom. 1998, 12, 1435.
14. Figeys, D.; Ning, Y.; Aebersold, R. Anal. Chem. 1997, 69, 3153-3160.
15. Henry, C. Anal. Chem. 1997, 69, A359-A361.
16. Li, J.; Kelly, J. F.; Chernushevich, I.; Harrison, D. J.; Thibault, P. Anal. Chem. 2000, 72, 599-609.
17. Li, J.; Thibault, P.; Bings, N. H.; Skinner, C. D.; Wang, C.; Colyer, C. L.; Harrison, D. J. Anal. Chem. 1999, 71, 3036-3045.
18. Schultz, G. A.; Corso, T. N.; Prosser, S. J.; Zhang, S. Anal. Chem. 2000, 72, 4058-4063.
19. Tachibana, Y.; Otsuka, K.; Terabe, S.; Arai, A.; Suzuki, K.; Nakamura, S. J. Chromatogr., A 2004, 1025, 287-296.
20. Thorslund, S.; Lindberg, P.; Andren, P. E.; Nikolajeff, F.; Bergquist, J. Electrophoresis 2005, 26, 4674-4683.
21. Xiang, f.; Lin, Y.; Wen, J.; Matson, D. W.; Smith, R. D. Anal. Chem. 1999, 71, 1485.
22. Xu, N.; Lin, Y.; Hofstadler, S. A.; Matson, D.; Call, C. J.; Smith, R. D. Anal. Chem. 1998, 70, 3553.
23. Zhang, B.; Foret, F.; Karger, B. L. Anal. Chem. 2001, 73, 2675-2681.
24. Zhang, B.; Liu, H.; Karger, B. L.; Foret, F. Anal. Chem. 1999, 71, 3258-3268.
25. Kelly, R. T.; Tang, K.; Irimia, D.; Toner, M.; Smith, R. D. Anal. Chem. In press.
26. Foret, F.; Kusy, P. Electrophoresis 2006, 27, 4877-4887.
27. Koster, S.; Verpoorte, E. Lab Chip 2007, 7, 1394-1412.
28. Lazar, I. M.; Grym, J.; Foret, F. Mass Spectrom. Rev. 2006, 25, 573-594.
29. Yin, H. F.; Killeen, K. J. Sep. Sci. 2007, 30, 1427-1434.
30. Yin, N. F.; Killeen, K.; Brennen, R.; Sobek, D.; Werlich, M.; van.de.Goor, T. V. Anal. Chem. 2005, 77, 527-533.
31. Lazar, I. M.; Ramsey, R. S.; Jacobson, S. C.; Foote, R. S.; Ramsey, J. M. J. Chromatogr., A 2000, 892, 195-201.
32. Ramsey, R. S.; Ramsey, J. M. Anal. Chem. 1997, 69, 1174-1178.
33. Xue, Q.; Foret, F.; Dunayevskiy, Y. M.; Zavracky, P. M.; McGruer, N. E.; Karger, B. L. Anal. Chem. 1997, 69, 426-430.
34. Mugele, F.; Baret, J. C. J. Phys.,Condens. Mater. 2005, 17, R705-R774.
35. Lazar, I. M.; Ramsey, R. S.; Ramsey, J. M. Anal. Chem. 2001, 73, 1733-1739.
36. Lazar, I. M.; Ramsey, R. S.; Sundberg, S.; Ramsey, J. M. Anal. Chem. 1999, 71, 3627-3631.
37. Hoffmann, P.; Hausig, U.; Schulze, P.; Belder, D. Angew. Chem., Int. Ed. 2007, 46, 4913-4916.
38. Lukacs, K. D.; Jorgenson, J. W. J. High Resolut. Chromatogr. Chromatogr. Commun. 1985, 8, 407-411.
39. Hardenbourg, E.; Zuberovic, A.; Ullsten, S.; Soderberg, L.; Heldin, E.; Markides, K. E. J. Chromatogr. A 2003, 1003, 217-221.
40. Ullsten, S.; Zuberovic, A.; Wetterhall, M.; Hardenbourg, E.; Markides, K. E.; Bergquist, J. Electrophoresis 2004, 25, 2090-2099.
41. Griffiths, S. K.; Nilson, R. H. Anal. Chem. 2001, 73, 272-278.
42. Molho, J. I.; Herr, A. E.; Mosier, B. P.; Santiago, J. G.; Kenny, T. W.; Brennen, R. A.; Gordon, G. B.; Mohammadi, B. Anal. Chem. 2001, 73, 1350-1360.
43. Ramsey, J. D.; Jacobson, S. C.; Culbertson, C. T.; Ramsey, J. M. Anal. Chem. 2003, 75, 3758-3764.
44. Sikanen, T.; Tuomikoski, S.; Ketola, R. A.; Kostiainen, R. Franssila, S.; Kotiaho, T. Anal. Chem. 2007, 79, 9135-9144.
45. Jacobson, S. C.; Koutny, L. B.; Hergenroder, R.; Moore, A. W.; Ramsey, J. M. Anal. Chem. 1994, 66, 3472-3476.