Characterization of drug-resistance mutations in HIV type 1 isolates from drug-naive and ARV-treated patients in Bulgaria

AIDS Research and Human Retroviruses

Volumn 24, Issue 9, 2008, Pages 1133-1138

  Santoro, Maria Mercedes ^a   Ciccozzi, Massimo ^b   Alteri, Claudia ^a   Montieri, Stefania ^b   Alexiev, Ivailo ^c   Dimova, Iordanka ^c   Ceccherini Silberstein, Francesca ^a   Beshkov, Danail ^c   Rezza, Giovanni ^b   Perno, Carlo Federico ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^c NATIONAL CENTER OF INFECTIOUS AND PARASITIC DISEASES   (Bulgaria)

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; AMPRENAVIR PHOSPHATE; ANTIRETROVIRUS AGENT; ATAZANAVIR; DARUNAVIR; DIDANOSINE; EMTRICITABINE; LAMIVUDINE; LOPINAVIR; NELFINAVIR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; TIPRANAVIR; ZIDOVUDINE;

ANTIVIRAL RESISTANCE; ARTICLE; BLOOD SAMPLING; BULGARIA; DECENTRALIZATION; GENE MUTATION; GENOTYPE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NUCLEOTIDE SEQUENCE; PHYLOGENY; PREVALENCE; PRIORITY JOURNAL; VIRUS ISOLATION;

AMINO ACID SUBSTITUTION; ANTI-RETROVIRAL AGENTS; BULGARIA; DRUG RESISTANCE, VIRAL; FEMALE; HIV INFECTIONS; HIV PROTEASE; HIV PROTEASE INHIBITORS; HIV REVERSE TRANSCRIPTASE; HIV-1; HUMANS; MALE; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; PLASMA; REVERSE TRANSCRIPTASE INHIBITORS; RNA, VIRAL; SEQUENCE ANALYSIS, DNA;

EID: 51849147107     PISSN: 08892229     EISSN: None     Source Type: Journal    
DOI: 10.1089/aid.2008.0042     Document Type: Article

References (19)

1. Palella FJ, Delaney KM, Moorman AC, et al.: Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med 1998;338:853-860.
2. Richman DD, Morton SC, Wrin T, et al.: The prevalence of antiretroviral drug resistance in the United States. AIDS 2004;18:1393-1401.
3. UNAIDS/WHO: UNAIDS epidemiological fact sheet update 2006.
4. Stanford University: Stanford University HIV Drug Resistance Database. Available from http://hivdb.stanford.edu. Update on 08/06/07.
5. Salemi M, Goodenow M, Montieri S, et al.: The HIV-1 epidemic in Bulgaria involves multiple subtypes and is sustained by continuous viral inflow from West and East European countries. AIDS Res Hum Retroviruses 2007;24(6): 771-779.
6. Johnson VA, Brun-Vezinet F, Clotet B, et al.: Update of the drug resistance mutations in HIV-1: 2007. Top HIV Med 2007;15:119-125.
7. Garcia-Lerma JG, Nidtha S, Blumoff K, Weinstock H, and Heneine W: Increased ability for selection of zidovudine resistance in a distinct class of wild-type HIV-1 from drug-naive persons. Proc Natl Acad Sci USA 2001;98:13907-13912.
8. Johnson VA, Brun-Vezinet F, Clotet B, Kuritzkes DR, Pillay D, Schapiro JM, and Richman DD: Update of the drug resistance mutations in HIV-1: Fall 2006. Top HIV Med 2006; 14(3):125-130.
9. Wensing AM, van de Vijver DA, Angarano G, et al.: Prevalence of drug-resistant HIV-1 variants in untreated individuals in Europe: Implications for clinical management. J Infect Dis 2005;192:958-966.
10. Ross L, Lim ML, Liao Q, et al.: Prevalence of antiretroviral drug resistance and resistance-associated mutations in antiretroviral therapy-naive HIV-infected individuals from 40 United States cities. HIV Clin Trials 2007;8:1-8.
11. Costagliola D, Descamps D, Assoumou L, et al.: Prevalence of HIV-1 drug resistance in treated patients: A French nationwide study. J Acquir Immune Defic Syndr 2007;46:12-18.
12. Balotta C, Facchi G, Violin M, et al.: Increasing prevalence of nonclade B HIV-1 strains in heterosexual men and women, as monitored by analysis of reverse transcriptase and protease sequences. J Acquir Immune Defic Syndr 2001;27:499-505.
13. Stanojevic M, Papa A, Papadimitriou E, et al.: HIV-1 subtypes in Yugoslavia. AIDS Res Hum Retroviruses 2002;18: 519-522.
14. Ciccozzi M, Gori C, Boros S, et al.: Molecular diversity of HIV in Albania. J Infect Dis 2005;192:475-479.
15. Saad MD, Shcherbinskaya AM, Nadai Y, et al.: Molecular epidemiology of HIV type 1 in Ukraine: Birthplace of an epidemic. AIDS Res Hum Retroviruses 2006;22:709-714.
16. Wegner SA, Brodine SK, Mascola JR, et al.: Prevalence of genotypic and phenotypic resistance to anti-retroviral drugs in a cohort of therapy-naive HIV-1-infected US military personnel. AIDS 2000;14:1009-1015.
17. Little SJ, Holte S, Routy JP, et al.: Antiretroviral-drug resistance among patients recently infected with HIV. N Engl J Med 2002;347:385-394.
18. Pires IL, Soares MA, Speranza FA, et al.: Prevalence of human immunodeficiency virus drug resistance mutations and subtypes in drug-naive, infected individuals in the army health service of Rio de Janeiro, Brazil. J Clin Microbiol 2004;42:426-430.
19. Turner D, Brenner B, Moisi D, et al.: Nucleotide and amino acid polymorphism at drug resistance sites in non-B subtype variants of human immunodeficiency virus type 1. Antimicrob Agents Chemother 2004;48:2993-2998.