Analytical method developed for measurement of dialkylphosphate metabolites in urine collected from children non-occupationally exposed to organophosphate pesticides in an agricultural community in Thailand

Bulletin of Environmental Contamination and Toxicology

Volumn 81, Issue 4, 2008, Pages 401-405

  Petchuay, Chidhathai ^a,b   Thoumsang, Somkiet ^c   Visuthismajarn, Parichart ^d   Vitayavirasak, Banjong ^d   Buckley, Brian ^e   Hore, Paromita ^f   Borjan, Marija ^f,g   Robson, Mark ^f,g  

^a UBON RATCHATHANI UNIVERSITY   (Thailand)

^b CHULALONGKORN UNIVERSITY   (Thailand)

^c Department of Disease Control   (Thailand)

^d PRINCE OF SONGKLA UNIVERSITY   (Thailand)

^e RUTGERS UNIVERSITY   (United States)

^f UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

^g RUTGERS UNIVERSITY   (United States)

Author keywords

Analytical method; Dialkyphosphate; Non occupational exposure; Organophosphate; Pesticide

Indexed keywords

AGRICULTURAL AREAS; ANALYTICAL METHOD; ANALYTICAL METHODS; BIOLOGICAL MONITORING; DIALKYPHOSPHATE; FARM WORKERS; NON-OCCUPATIONAL EXPOSURE; ORGANOPHOSPHATE; ORGANOPHOSPHATE PESTICIDES; PESTICIDE; PESTICIDE EXPOSURE; THAILAND;

BIOMOLECULES; BODY FLUIDS; METABOLITES;

PESTICIDES;

DIALKYLPHOSPHATE; ORGANOPHOSPHATE PESTICIDE; PHOSPHATE; UNCLASSIFIED DRUG;

AGRICULTURAL WORKER; AGRICULTURE; ANALYTIC METHOD; ARTICLE; BIOLOGICAL MONITORING; ENVIRONMENTAL EXPOSURE; FEMALE; FREEZE DRYING; GAS CHROMATOGRAPHY; HUMAN; MALE; PRESCHOOL CHILD; RURAL AREA; THAILAND; URINALYSIS;

AGRICULTURE; CHILD; CHROMATOGRAPHY, GAS; ENVIRONMENTAL EXPOSURE; FREEZE DRYING; HUMANS; INDICATORS AND REAGENTS; ORGANOPHOSPHORUS COMPOUNDS; PESTICIDE RESIDUES; PHOTOMETRY; REFERENCE STANDARDS; SOLUTIONS; TEMPERATURE; THAILAND;

EID: 51849130259     PISSN: 00074861     EISSN: 14320800     Source Type: Journal    
DOI: 10.1007/s00128-008-9515-5     Document Type: Article

References (14)

1. C Aprea G Sciarra L Lunghini 1996 Analytical method for the determination of urinary alkylphosphates in subjects occupationally exposed to organophosphorus pesticides and in the general population J Anal Toxicol 20 559 563
2. DB Barr LL Needham 2002 Analytical methods for biological monitoring of exposure to pesticides: a review J Chromatogr B 778 5 29 10.1016/S1570-0232(02) 00035-1
3. R Bravo LM Caltabiano G Weerasekera RD Whitehead C Fernandez LL Needham A Bradman DB Barr 2004 Measurement of dialkyl phosphate metabolites of organophosphorus pesticides in human urine using lyophilization with gas chromatography-tandem mass spectrometry and isotope dilution quantification J Expo Anal Environ Epidemiol 14 249 259 10.1038/sj.jea.7500322
4. RA Fenske C Lu NJ Simcox JT Loewenherz TF Moate EH Allen JC Kissel 2000 Strategies for assessing children's organophosphorus pesticide exposures in agricultural communities J Expo Anal Environ Epidemiol 10 662 671
5. J Hardt J Angerer 2000 Determination of dialkyl phosphates in human urine using gas chromatography-mass spectrometry J Anal Toxicol 24 678 684
6. Integrated Pest Management (IPM) Thailand (2003) Did you take your poison today? A report by the IPM DANIDA project. http://www.ipmthailand.org
7. Loewenherz C, Fenske RA, Simcox NJ, Bellamy G, Kalman D (1997) Biological monitoring of organophosphorus pesticide exposure among children of agricultural workers in central Washington State. Environ Health Perspect 105:1344-1353
8. C Lu DE Knutson JF Anderson RA Fenske 2001 Biological monitoring of organophosphorus pesticide exposure among preschool children in the seattle metropolitan area Environ Health Perspect 109 299 303 10.2307/3434700
9. TF Moate C Lu RA Fenske RMA Hahne DA Kalman 1999 Improved cleanup and determination of dialkyl phosphates in the urine of children exposed to organophosphorus insecticides J Anal Toxicol 23 230 236
10. BP Nutley J Cocker 1993 Biological monitoring of workers occupationally exposed to organophosphorus pesticides Pestic Sci 38 315 322 10.1002/ps.2780380406
11. AN Oglobine H Elimelakh B Tattam R Geyer GE O'Donnell G Holder 2001 Negative ion chemical ionization GC/MS-MS analysis of dialkylphosphate metabolites of organophosphate pesticides in urine of non-occupationally exposed subjects Analyst 126 1037 1041 10.1039/b102004h
12. AN Oglobine GE O'Donnell R Geyer GM Holder B Tattam 2001 Routine gas chromatographic determination of dialkylphosphate metabolites in the urine of workers occupationally exposed to organophosphorus insecticides J Anal Toxicol 25 153 157
13. R Stiles I Yang RL Lippincott E Murphy B Buckley 2007 Identifying potential sources of background contaminants resulting from solid phase extraction and solid phase microextraction J Sep Sci 30 1029 1036 10.1002/jssc.200600358
14. Weisskopf CP, Seiber J (1989) New approaches to analysis of organophosphate metabolites in the urine of field workers. In: Wang RG, Franklin CA, Honeycutt RC, Reinert C (eds) Biological monitoring for pesticide exposure. Measurement, estimation and risk reduction. American Chemical Society, Washington DC, pp 206-214