Binomial mitotic segregation of MYCN-carrying double minutes in neuroblastoma illustrates the role of randomness in oncogene Amplification

PLoS ONE

Volumn 3, Issue 8, 2008, Pages

  Lundberg, Gisela ^a   Rosengren, Anders H ^b   Håkanson, Ulf ^c   Stewénius, Henrik ^d   Jin, Yuesheng ^a   Stewénius, Ylva ^a   Påhlman, Sven ^d   Gisselsson, David ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b LUND UNIVERSITY   (Sweden)

^c LUND UNIVERSITY   (Sweden)

^d LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOPROTEIN; ONCOPROTEIN; PROTEIN MYCN; UNCLASSIFIED DRUG; MYCN PROTEIN, HUMAN; NUCLEAR PROTEIN;

ANAPHASE; ANIMAL CELL; ARTICLE; BINOMIAL DISTRIBUTION; CELL DIVISION; CELL GROWTH; CELL HYBRIDIZATION; CELL PROLIFERATION; CHROMOSOME STRUCTURE; COLONY FORMING CELL; CONTROLLED STUDY; DOUBLE MINUTE CHROMOSOME; GENE AMPLIFICATION; GENE NUMBER; GENE SEQUENCE; HUMAN; HUMAN CELL; INTERPHASE; MATHEMATICAL MODEL; MITOSIS; MOUSE; NEUROBLASTOMA; NEUROBLASTOMA CELL; NONHUMAN; PROPHASE; PROTEIN BINDING; RANDOMIZATION; TELOMERE; TELOPHASE; ATOMIC FORCE MICROSCOPY; CELL CYCLE; CHROMOSOME SEGREGATION; FLUORESCENCE IN SITU HYBRIDIZATION; FLUORESCENCE MICROSCOPY; GENETIC VARIABILITY; GENETICS; MUTATION; ONCOGENE MYC; PATHOLOGY; TUMOR CELL LINE; ULTRASTRUCTURE;

MURINAE;

CELL CYCLE; CELL LINE, TUMOR; CHROMOSOME SEGREGATION; GENE AMPLIFICATION; GENES, MYC; GENETIC VARIATION; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MICROSCOPY, ATOMIC FORCE; MICROSCOPY, FLUORESCENCE; MITOSIS; MUTATION; NEUROBLASTOMA; NUCLEAR PROTEINS; ONCOGENE PROTEINS; RANDOM ALLOCATION;

EID: 51849083862     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0003099     Document Type: Article

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