A single amino acid substitution in one of the lipases of aspergillus nidulans confers resistance to the antimycotic drug undecanoic acid

Biochemical Genetics

Volumn 46, Issue 9-10, 2008, Pages 557-565

  Brito Madurro, Ana G ^a   Prade, Rolf A ^b   Madurro, João M ^a   Santos, Mário A ^c   Peres, Nalu T A ^d   Cursino Santos, Jeny R ^d   Martinez Rossi, Nilce M ^d   Rossi, Antonio ^d  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b OKLAHOMA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF LISBON   (Portugal)

^d UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Antifungal resistance; Aspergillus nidulans; LipA gene; Lipase; Undecanoic acid

Indexed keywords

FATTY ACID; GENOMIC DNA; LYSINE; MESSENGER RNA; TRIACYLGLYCEROL LIPASE; UNDECANOIC ACID;

AMINO ACID SUBSTITUTION; ARTICLE; ASPERGILLUS NIDULANS; CONTROLLED STUDY; DRUG EFFECT; DRUG RESISTANCE; ENZYME ACTIVITY; FUNGAL GENE; FUNGAL STRAIN; FUNGUS GROWTH; GENE MUTATION; INTRON; LIPA GENE; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME;

AMINO ACID SEQUENCE; AMINO ACIDS; ANTIFUNGAL AGENTS; ASPERGILLUS NIDULANS; CARBOXYLIC ESTER HYDROLASES; CATALYTIC DOMAIN; DRUG RESISTANCE, FUNGAL; FATTY ACIDS; GENETIC TECHNIQUES; GLUTAMIC ACID; IONS; LIPASE; LYSINE; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; SEQUENCE HOMOLOGY, AMINO ACID;

EMERICELLA NIDULANS;

EID: 51749106121     PISSN: 00062928     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10528-008-9170-x     Document Type: Article

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