Ran suppresses paclitaxel-induced apoptosis in human glioblastoma cells

Apoptosis

Volumn 13, Issue 10, 2008, Pages 1223-1231

  Woo, Im Sun ^a   Jang, Han Su ^b   Eun, So Young ^a   Kim, Hyo Jung ^a   Ham, Sun Ah ^a   Kim, Hye Jung ^a   Lee, Jae Heun ^a   Chang, Ki Churl ^a   Kim, Jin Hoi ^c   Han, Chang Woo ^d   Seo, Han Geuk ^a  

^a Gyeongsang National University School of Medicine   (South Korea)

^b Gyeongbuk Institute for Bio industry   (South Korea)

^c Konkuk University   (South Korea)

^d Dongguk University Ilsan Hospital   (South Korea)

Author keywords

Apoptosis; Glioblastoma; Paclitaxel; Ran

Indexed keywords

CASPASE 3; COMPLEMENTARY DNA; CYTOCHROME C; MITOGEN ACTIVATED PROTEIN KINASE P38; PACLITAXEL; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; RAN PROTEIN; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CONTROLLED STUDY; ENZYME INHIBITION; FLUORESCENCE ACTIVATED CELL SORTING; GENE OVEREXPRESSION; GLIOBLASTOMA; HUMAN; HUMAN CELL; PRIORITY JOURNAL; YEAST CELL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; CELL LINE, TUMOR; ENZYME ACTIVATION; G1 PHASE; GENE LIBRARY; GLIOBLASTOMA; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; PACLITAXEL; PROTO-ONCOGENE PROTEINS C-AKT; RAN GTP-BINDING PROTEIN; REACTIVE OXYGEN SPECIES; SACCHAROMYCES CEREVISIAE;

EID: 51749086359     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-008-0247-0     Document Type: Article

References (31)

1. MC Raff 1992 Social controls on cell survival and cell death Nature 356 397 400 10.1038/356397a0
2. H Okada TW Mak 2004 Pathways of apoptotic and non-apoptotic death in tumour cells Nat Rev Cancer 4 592 603 10.1038/nrc1412
3. S Elmore 2007 Apoptosis: a review of programmed cell death Toxicol Pathol 35 495 516 10.1080/01926230701320337
4. L during apoptosis Proc Natl Acad Sci USA 94 3668 3672 10.1073/pnas.94.8.3668
5. Q Xu JC Reed 1998 Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast Mol Cell 1 337 346 10.1016/S1097-2765(00)80034-9
6. M Sawada W Sun P Hayes K Leskov DA Boothman S Matsuyama 2003 Ku70 suppresses the apoptotic translocation of Bax to mitochondria Nat Cell Biol 5 320 329 10.1038/ncb950
7. Z Yang C Khoury G Jean-Baptiste MT Greenwood 2006 Identification of mouse sphingomyelin synthase 1 as a suppressor of Bax-mediated cell death in yeast FEMS Yeast Res 6 751 762 10.1111/j.1567-1364.2006.00052.x
8. H Moon D Baek B Lee DT Prasad SY Lee MJ Cho 2002 Soybean ascorbate peroxidase suppresses Bax-induced apoptosis in yeast by inhibiting oxygen radical generation Biochem Biophys Res Commun 290 457 462 10.1006/bbrc.2001.6208
9. SC Kampranis R Damianova M Atallah G Toby G Kondi PN Tsichlis 2000 A novel plant glutathione S-transferase/peroxidase suppresses Bax lethality in yeast J Biol Chem 275 29207 29216 10.1074/jbc.M002359200
10. EA Eisenhauer JB Vermorken 1998 The taxoids. Comparative clinical pharmacology and therapeutic potential Drugs 55 5 30 10.2165/00003495-199855010- 00002
11. C Bokemeyer JT Hartmann MA Kuczyk MC Truss C Kollmannsberger J Beyer 1998 Recent strategies for the use of paclitaxel in the treatment of urological malignancies World J Urol 16 155 162 10.1007/s003450050044
12. PB Schiff J Fant SB Horwitz 1979 Promotion of microtubles assembly in vitro by taxol Nature 277 665 667 10.1038/277665a0
13. N André M Carré G Brasseur B Pourroy H Kovacic C Briand 2002 Paclitaxel targets mitochondria upstream of caspase activation in intact human neuroblastoma cells FEBS Lett 532 256 260 10.1016/S0014-5793(02)03691-8
14. YF Wang CY Chen SF Chung YH Chiou HR Lo 2004 Involvement of oxidative stress and caspase activation in paclitaxel-induced apoptosis of primary effusion lymphoma cells Cancer Chemother Pharmacol 54 322 330 10.1007/s00280-004-0831-0
15. VM Pushkarev DV Starenki VA Saenko H Namba J Kurebayashi MD Tronko 2004 Molecular mechanisms of the effects of low concentrations of taxol in anaplastic thyroid cancer cells Endocrinology 145 3143 3152 10.1210/en.2004-0127
16. FR Bischoff H Ponstingl 1991 Mitotic regulator protein RCC1 is complexed with a nuclear ras-related polypeptide Proc Natl Acad Sci USA 88 10830 10834 10.1073/pnas.88.23.10830
17. DJ Sweet L Gerace 1996 A GTPase distinct from Ran is involved in nuclear protein import J Cell Biol 133 971 983 10.1083/jcb.133.5.971
18. FR Bischoff H Ponstingl 1995 Catalysis of guanine nucleotide exchange of Ran by RCC1 and stimulation of hydrolysis of Ran-bound GTP by Ran-GAP1 Meth Enzymol 257 135 144 10.1016/S0076-6879(95)57019-5
19. P Kalab RT Pu M Dasso 1999 The Ran GTPase regulates mitotic spindle assembly Curr Biol 9 481 484 10.1016/S0960-9822(99)80213-9
20. J Joseph 2006 Ran at a glance J Cell Sci 119 3481 3484 10.1242/jcs.03071
21. MG Rush G Drivas P D'Eustachio 1996 The small nuclear GTPase Ran: how much does it run? Bioessays 18 103 112 10.1002/bies.950180206
22. K Azuma T Sasada H Takedatsu H Shomura M Koga Y Maeda 2004 Ran, a small GTPase gene, encodes cytotoxic T lymphocyte (CTL) epitopes capable of inducing HLA-A33 restricted and tumor-reactive CTLs in cancer patients Clin Cancer Res 10 6695 6702 10.1158/1078-0432.CCR-04-0818
23. J Hill KA Ian G Donald DE Griffiths 1991 DMSO-enhanced whole cell yeast transformation Nucleic Acids Res 19 5791 10.1093/nar/19.20.5791
24. ES Kang IS Woo HJ Kim SY Eun KS Paek HJ Kim 2007 Up-regulation of aldose reductase expression mediated by phosphatidylinositol 3-kinase/Akt and Nrf2 is involved in the protective effect of curcumin against oxidative damage Free Radic Biol Med 43 535 545 10.1016/j.freeradbiomed.2007.05.006
25. ML Brezniceanu K Volp S Bosser C Solbach P Lichter S Joos 2003 HMGB1 inhibits cell death in yeast and mammalian cells and is abundantly expressed in human breast carcinoma FASEB J 17 1295 1297
26. 2-terminal kinase (JNK/SAPK) J Biol Chem 273 28253 28260 10.1074/jbc.273.43.28253
27. F Tsuruta J Sunayama Y Mori S Hattori S Shimizu U Tsujimoto 2004 JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins EMBO J 23 1889 1899 10.1038/sj.emboj.7600194
28. L Briches G Cazettes A Valette 2004 JNK is associated with Bcl-2 and PP1 in mitochondria Cell Cycle 3 e47 e54
29. L protein levels Cell Death Differ 7 574 586 10.1038/sj.cdd.4400688
30. G Varbiro B Veres F Gallyas Jr B Sumegi 2001 Direct effect of taxol on free radical formation and mitochondrial permeability transition Free Radic Biol Med 31 548 558 10.1016/S0891-5849(01)00616-5
31. SJ Park CH Wu JD Gordon X Zhong A Emami AR Safa 2004 Taxol induces caspase-10-dependent apoptosis J Biol Chem 279 51057 51067 10.1074/jbc. M406543200