Renal phosphate-transporter regulatory proteins and nephrolithiasis

New England Journal of Medicine

Volumn 359, Issue 11, 2008, Pages 1171-1173

  Levi, Moshe ^a   Bruesegem, Sophia ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL; CALCIUM; CALCIUM PHOSPHATE; PARATHYROID HORMONE RECEPTOR 1; PHOSPHATE TRANSPORTER; SODIUM PHOSPHATE COTRANSPORTER; CYCLIC AMP; PHOSPHATE; PHOSPHOPROTEIN; SODIUM HYDROGEN EXCHANGER REGULATORY FACTOR; SODIUM PROTON EXCHANGE PROTEIN; SODIUM-HYDROGEN EXCHANGER REGULATORY FACTOR;

CALCIUM ABSORPTION; EDITORIAL; GENE MUTATION; HYPERCALCIURIA; HYPOPHOSPHATEMIA; NEPHROLITHIASIS; NONHUMAN; PHOSPHATE BLOOD LEVEL; PHOSPHATE TRANSPORT; PHOSPHATURIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RICKETS; VITAMIN BLOOD LEVEL; ANIMAL; BONE DEMINERALIZATION; GENETICS; HUMAN; KIDNEY; METABOLISM; MOUSE; MOUSE MUTANT; MUTATION; NOTE; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; BONE DEMINERALIZATION, PATHOLOGIC; CYCLIC AMP; HUMANS; HYPERCALCIURIA; KIDNEY; MICE; MICE, KNOCKOUT; MUTATION; NEPHROLITHIASIS; PHOSPHATES; PHOSPHOPROTEINS; SODIUM-HYDROGEN ANTIPORTER;

EID: 51649116923     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMe0805943     Document Type: Editorial

References (15)

1. Tessier J, Petrucci M, Trouvé ML, et al. A family-based study of metabolic phenotypes in calcium urolithiasis. Kidney Int 2001;60:1141-7.
2. Prié D, Ravery V, Boccon-Gibod L, Friedlander G. Frequency of renal phosphate leak among patients with calcium nephrolithiasis. Kidney Int 2001;60:272-6.
3. Iwaki T, Sandoval-Cooper MJ, Tenehouse HS, Castellino FJ. A missense mutation in the sodium phosphate co-transporter Slc34a1 impairs phosphate homeostasis. J Am Soc Nephrol 2008 June 11 (Epub ahead of print).
4. Prié D, Huart V, Bakouh N, et al. Nephrolithiasis and osteoporosis associated with hypophosphatemia caused by mutations in the type 2 sodium-phosphate cotransporter. N Engl J Med 2002;347:983-91.
5. Lapointe JY, Tessier J, Paquette Y, et al. NPT2a gene variation in calcium nephrolithiasis with renal phosphate leak. Kidney Int 2006;69:2261-7.
6. Juareguiberry G, Carpenter TO, Forman S, Jüppner H, Bergwitz C. A novel missense mutation in SLC34A3 that causes hereditary hypophosphatemic rickets with hypercalciuria in humans identifies threonine 137 as an important determinant of sodium-phosphate cotransport in NaPi-IIc. Am J Physiol Renal Physiol 2008;295:F371-F379.
7. Karim Z, Gérard B, Bakouh N, et al. Human NHERF1 mutations and responsiveness of the renal parathyroid hormone. N Engl J Med 2008;359:1128-35.
8. Hernando N, Gisler SM, Pribanic S, et al. NaPi-IIa and interacting partners. J Physiol 2005;567:21-6.
9. Villa-Bellosta R, Barac-Nieto M, Breusegem SY, Barry NP, Levi M, Sorribas V. Interactions of the growth-related, type IIc renal sodium/phosphate cotransporter with PDZ proteins. Kidney Int 2008;73:456-64.
10. Khundmiri SJ, Ahmad A, Bennett RE, et al. Novel regulatory function for NHERF-1 in Npt2a transcription. Am J Physiol Renal Physiol 2008;294:F840-F849.
11. Weinman EJ, Biswas RS, Peng G, et al. Parathyroid hormone inhibits renal phosphate transport by phosphorylation of serine 77 of sodium-hydrogen exchanger regulatory factor-1. J Clin Invest 2007;117:3412-20. [Erratum, J Clin Invest 2008;118:387.]
12. Cunningham R, Brazie M, Kanumuru S, et al. Sodium-hydrogen exchanger regulatory factor-1 interacts with mouse urate transporter 1 to regulate renal proximal tubule uric acid transport. J Am Soc Nephrol 2007;18:1419-25.
13. Gisler SM, Kittanakom S, Fuster D, et al. Monitoring protein-protein interactions between the mammalian integral membrane transporters and PDZ-interacting partners using a modified split-ubiquitin membrane yeast two-hybrid system. Mol Cell Proteomics 2008;7:1362-77.
14. Jentsch TJ. CLC chloride channels and transporters: from genes to protein structure, pathology and physiology. Crit Rev Biochem Mol Biol 2008;43:3-36.
15. Segawa H, Yamanaka S, Ohno Y, et al. Correlation between hyperphosphatemia and type II Na-Pi cotransporter activity in Klotho mice. Am J Physiol Renal Physiol 2007;292:F769-F779.